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The map label for this gene is pncB [H]

Identifier: 115351030

GI number: 115351030

Start: 1065447

End: 1066646

Strand: Direct

Name: pncB [H]

Synonym: Bamb_0976

Alternate gene names: 115351030

Gene position: 1065447-1066646 (Clockwise)

Preceding gene: 115351023

Following gene: 115351031

Centisome position: 29.96

GC content: 63.42

Gene sequence:

>1200_bases
ATGATCATCACTTCGCTGCTCGACACGGATCTCTACAAGTTCACGATGATGCAGGTCGTCCTGCATCACTTTCCCGCCGC
AAACGTCGAGTACCGGTTCCGGTGCCGCACGCCCGGCGTCGATCTCGTCCCGTACATCGACGAGATTCGCGACGAGGTGC
GCGGCCTCTGTTCGCTGCGCTTCACCGACGTCGAATTGGACTACTTGCGACGGATGCGCTTCATCAAGAGCGATTTCGTC
GACTTCCTCGCGCTGTTCCACCTGAACGAGAAGTACATCTCGATCACGCCCTCGCCGAAGGGCAACGGCGAGATCGACAT
CGTGATCGAGGGGCCGTGGCTGCACACGATCCTGTTCGAGATCCCGGTGCTCGCGATCGTCAATGAGGTCTATTTCCGCA
ACACGCAGCGCGAGCCCGACTATCGCGAAGGCCGCGAGCGGCTGCGCGAGAAGATCAAGCTGCTCGGCGCGAAGCCCGAG
TTCGCCGACTGCAAGATCGCCGACTACGGCACGCGCCGACGCTTCTCGAAGGTGTGGCACGAGGAGGTCGCGCTGACGCT
GCGCGACGGGCTCGGGCCGCAGTTCGCGGGCACGAGTAACGTGTTCTACGCGATGAAGCACGAGCTGACGCCGCTCGGCA
CGATGGCGCACGAATACCTGCAGGCATGCCAGGCGCTCGGCCCGCGGCTGCGCGATTCGCAGACTTACGGTTTCGAGATG
TGGGCGAAGGAGTATCGTGGCGACCTCGGGATCGCGCTGTCGGACGTCTACGGGATGGATGCGTTCCTGAACGACTTCGA
CATGTACTTCTGCAAGCTGTTCGACGGCGCGCGCCACGATTCGGGCGACCCGTTCGAGTGGGGCGAGCGCATGCTGCGCC
ACTACGAGGCGAACCGCTGCGACCCGCGCACCAAGGTGCTCGTGTTCTCGGATGCGCTCGACATTCCGAAGGTCATGCAG
CTGTACGAACGGTTCCGCAACCGCTGCAAGCTCGCGTTCGGCGTCGGCACCAATCTCACGAACGATCTCGGCTACGTGCC
GCTGCAGATCGTGATCAAGATGGTCCGCTGCAACGGCCAGCCGGTCGCGAAGCTGTCGGATTCGCCGGGCAAGAGCATGT
GCGACGACCGCGCGTATCTCGCGTACCTGCGCCAGGTGTTCGGCATCGCGCAGCCGGCCGACGACGACGCATCGCAGTAG

Upstream 100 bases:

>100_bases
GCTTTCACGATGGTCCGGCCCGCATTCGGGTAACATGGCCGACAGACCGGGCGGCGCGCGGTGTGCCGGACCCTGTCTCG
ATATTGGCGGTGCCGTAATC

Downstream 100 bases:

>100_bases
GCGTCGGCCGTTCGGCCTGGTGCGTCGCGGCGAGGGCGGCCGGTATAATCCGACGATATCGCACGCTCATGTCACGAGGA
CCGTTCATGGACACTTCCGC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFTDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVFYAMKHELTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQ
LYERFRNRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDRAYLAYLRQVFGIAQPADDDASQ

Sequences:

>Translated_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFTDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVFYAMKHELTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQ
LYERFRNRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDRAYLAYLRQVFGIAQPADDDASQ
>Mature_399_residues
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLRFTDVELDYLRRMRFIKSDFV
DFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFEIPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPE
FADCKIADYGTRRRFSKVWHEEVALTLRDGLGPQFAGTSNVFYAMKHELTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRCDPRTKVLVFSDALDIPKVMQ
LYERFRNRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDRAYLAYLRQVFGIAQPADDDASQ

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=393, Percent_Identity=43.5114503816794, Blast_Score=327, Evalue=8e-91,
Organism=Saccharomyces cerevisiae, GI6324783, Length=402, Percent_Identity=29.8507462686567, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46111; Mature: 46111

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCE
FTDVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFE
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGPQFAGTSNVFYAMKHELTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
HHHHHHHHHCCCCCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVMQLYERFRNRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDRAYLAYLRQVFGIAQPADDDASQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIITSLLDTDLYKFTMMQVVLHHFPAANVEYRFRCRTPGVDLVPYIDEIRDEVRGLCSLR
CEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCE
FTDVELDYLRRMRFIKSDFVDFLALFHLNEKYISITPSPKGNGEIDIVIEGPWLHTILFE
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCHHHHHHHH
IPVLAIVNEVYFRNTQREPDYREGRERLREKIKLLGAKPEFADCKIADYGTRRRFSKVWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
EEVALTLRDGLGPQFAGTSNVFYAMKHELTPLGTMAHEYLQACQALGPRLRDSQTYGFEM
HHHHHHHHHCCCCCCCCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
WAKEYRGDLGIALSDVYGMDAFLNDFDMYFCKLFDGARHDSGDPFEWGERMLRHYEANRC
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVMQLYERFRNRCKLAFGVGTNLTNDLGYVPLQIVIKMVRCNGQ
CCCCEEEEEECCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCC
PVAKLSDSPGKSMCDDRAYLAYLRQVFGIAQPADDDASQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA