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The map label for this gene is atoC [H]

Identifier: 115351014

GI number: 115351014

Start: 1049696

End: 1051093

Strand: Direct

Name: atoC [H]

Synonym: Bamb_0960

Alternate gene names: 115351014

Gene position: 1049696-1051093 (Clockwise)

Preceding gene: 115351011

Following gene: 115351015

Centisome position: 29.51

GC content: 67.53

Gene sequence:

>1398_bases
ATGGGAGCCGAGCAGCGGCATGTGATCTATTTCTCGCGCGAGCCGAACGACGCGTTGCGCGGGCATTTCGACGAATGCGG
ATGGTGCGTCGATCTCGCGGAAAGCGCACGCGACTTGCGGCGTGTCGTGCAGCACGGCGTGGCATCCGCCGGCCTGCTCG
ATTTCTCGCCGGGTTTCAGGCCCGCGGATCTGCGCGAACTCGAAGCGTGTCTGAGCATCCAGCACATCGGCTGGATCGCG
GCGACCCGGCGTGGCCAGTTGCAGGACGCCACGTTGCGCCATCTCATCCGTGACTATTGCTTCGACTACGTGACGATGCC
GTACGAGACGTCGCGCATCGTCGAGACCGTCGGCCACGCGCACGGCATGATCGCGCTGACCGACCCGGTGGCGTCGCCGG
TCGGCGCGGGGCGCACCGAAGGCGAGATGGTCGGCACCTGCGATGCGATGCTCGGCCTTTTCAGGACGATCCGGCGCGTC
GCGACCACCGATGCGCCGGTGTTCATCTCCGGTGAATCGGGTACCGGCAAGGAGCTGACGGCCGTCGCGATTCACGAGCG
CTCGGCGCGCGCGCAGGCGCCGTTCGTCGCGATCAACTGCGGGGCGATTCCGTCGACGCTGCTGCAAGCCGAACTGTTCG
GCTATGAGCGCGGCGCGTTTACGGGCGCGAACCAGCGCAAGATCGGCCGCGTCGAGGCCGCGAACGGCGGCACGCTGTTT
CTCGACGAAATCGGCGACCTGCCGCTCGAGAGCCAGGCGAGCCTCCTGCGGTTCCTGCAGGAAGGCAAGATCGAGCGGCT
CGGCGCGCATGTATCGGTGCCGGTCGACGTGCGCGTGATCTGCGCGACGCATGTGGACATGGAAACGGCGCTGCGCGAAG
GGCGCTTCCGCGAGGATCTGTTCCATCGTCTGTGCGTGCTGAAGATCGAGGAGCCGCCGCTGCGCGCGCGCGGCAAGGAC
ATCGAGGTGCTCGCTCGCCACATGCTCGAGCGTTTCAAGGGCGATGCGCATCGTCGCTTGCGTGGCTTCTCTCCGGACGC
GATCGCCGCGCTGTACGGCTATTCGTGGCCGGGCAACGTGCGCGAGCTGATTAATCGCGTGCGCCGCGCGATCGTGATGT
CGGAGGGCCGGATGATTACCGCGGCCGATCTCGAGCTCCACGAATTCGCGATACTGGCGCCCGTCTCGCTCACCGAGGCG
CGGGAAGCGGCCGAGCGGCAGGCGATCGAGCAGGCGCTGCTGCGTCATCGCGGCCGTTTTGCCGATGCGGCGCGTGAGCT
CGGCGTGTCGCGCGTCACGCTGTACAGGCTGATGTGCGCGCATGGCATGCGCGATCGCGGCGACACGCTGGCAGGGTTTT
CGGCGCCGGCGCCGGAGGTTCCGCGTCACGCTTGCTAA

Upstream 100 bases:

>100_bases
CATGGCGAATCGAGCGGCTTCGGCTGACCCGGTTCGATCCTTTTGCACGTGACTTCGCACGTGCGGCAATCGTTAGACGG
TTGATGAACGGGGTGGGCAT

Downstream 100 bases:

>100_bases
AATTGGCGGGTGACGGCCGCCCTCGCGGCCGAAGGAACCCGCATGAAACAGTACCTCGACCTCGTTCGCACCATCCTCGA
CACCGGCACCTGGCAGGAGA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MGAEQRHVIYFSREPNDALRGHFDECGWCVDLAESARDLRRVVQHGVASAGLLDFSPGFRPADLRELEACLSIQHIGWIA
ATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHAHGMIALTDPVASPVGAGRTEGEMVGTCDAMLGLFRTIRRV
ATTDAPVFISGESGTGKELTAVAIHERSARAQAPFVAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMETALREGRFREDLFHRLCVLKIEEPPLRARGKD
IEVLARHMLERFKGDAHRRLRGFSPDAIAALYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELHEFAILAPVSLTEA
REAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPAPEVPRHAC

Sequences:

>Translated_465_residues
MGAEQRHVIYFSREPNDALRGHFDECGWCVDLAESARDLRRVVQHGVASAGLLDFSPGFRPADLRELEACLSIQHIGWIA
ATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHAHGMIALTDPVASPVGAGRTEGEMVGTCDAMLGLFRTIRRV
ATTDAPVFISGESGTGKELTAVAIHERSARAQAPFVAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMETALREGRFREDLFHRLCVLKIEEPPLRARGKD
IEVLARHMLERFKGDAHRRLRGFSPDAIAALYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELHEFAILAPVSLTEA
REAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPAPEVPRHAC
>Mature_464_residues
GAEQRHVIYFSREPNDALRGHFDECGWCVDLAESARDLRRVVQHGVASAGLLDFSPGFRPADLRELEACLSIQHIGWIAA
TRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHAHGMIALTDPVASPVGAGRTEGEMVGTCDAMLGLFRTIRRVA
TTDAPVFISGESGTGKELTAVAIHERSARAQAPFVAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLFL
DEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMETALREGRFREDLFHRLCVLKIEEPPLRARGKDI
EVLARHMLERFKGDAHRRLRGFSPDAIAALYGYSWPGNVRELINRVRRAIVMSEGRMITAADLELHEFAILAPVSLTEAR
EAAERQAIEQALLRHRGRFADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPAPEVPRHAC

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=358, Percent_Identity=40.5027932960894, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1790437, Length=355, Percent_Identity=43.3802816901408, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1790299, Length=374, Percent_Identity=41.4438502673797, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788905, Length=346, Percent_Identity=39.8843930635838, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI87082117, Length=324, Percent_Identity=42.2839506172839, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=43.1309904153355, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI87082152, Length=338, Percent_Identity=43.1952662721894, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.2597402597403, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=43.8095238095238, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=43.1623931623932, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787583, Length=316, Percent_Identity=35.4430379746835, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=34.1296928327645, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1789828, Length=240, Percent_Identity=35.8333333333333, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51347; Mature: 51216

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAEQRHVIYFSREPNDALRGHFDECGWCVDLAESARDLRRVVQHGVASAGLLDFSPGFR
CCCCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PADLRELEACLSIQHIGWIAATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HGMIALTDPVASPVGAGRTEGEMVGTCDAMLGLFRTIRRVATTDAPVFISGESGTGKELT
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSARAQAPFVAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEEHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMETALREGRFREDL
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCEEEEEEECCCHHHHHHCCCHHHHH
FHRLCVLKIEEPPLRARGKDIEVLARHMLERFKGDAHRRLRGFSPDAIAALYGYSWPGNV
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMITAADLELHEFAILAPVSLTEAREAAERQAIEQALLRHRGRF
HHHHHHHHHHHHHCCCCEEEEECCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCH
ADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPAPEVPRHAC
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GAEQRHVIYFSREPNDALRGHFDECGWCVDLAESARDLRRVVQHGVASAGLLDFSPGFR
CCCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PADLRELEACLSIQHIGWIAATRRGQLQDATLRHLIRDYCFDYVTMPYETSRIVETVGHA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
HGMIALTDPVASPVGAGRTEGEMVGTCDAMLGLFRTIRRVATTDAPVFISGESGTGKELT
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEE
AVAIHERSARAQAPFVAINCGAIPSTLLQAELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEEHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQEGKIERLGAHVSVPVDVRVICATHVDMETALREGRFREDL
EECCCCCCCCHHHHHHHHHHHCCHHHCCCEEECCCCEEEEEEECCCHHHHHHCCCHHHHH
FHRLCVLKIEEPPLRARGKDIEVLARHMLERFKGDAHRRLRGFSPDAIAALYGYSWPGNV
HHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRMITAADLELHEFAILAPVSLTEAREAAERQAIEQALLRHRGRF
HHHHHHHHHHHHHCCCCEEEEECCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCH
ADAARELGVSRVTLYRLMCAHGMRDRGDTLAGFSAPAPEVPRHAC
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]