Click here to switch to the map view.

The map label for this gene is pmbA [H]

Identifier: 115351011

GI number: 115351011

Start: 1046622

End: 1047992

Strand: Direct

Name: pmbA [H]

Synonym: Bamb_0957

Alternate gene names: 115351011

Gene position: 1046622-1047992 (Clockwise)

Preceding gene: 115351008

Following gene: 115351014

Centisome position: 29.43

GC content: 68.78

Gene sequence:

>1371_bases
ATGGCAGCCAATCTCGACGTACAAGCGCGCTATTTCCCGCACACGCAGGACCAGCTCAAAGAAATTGCCTCCGACATCCT
CCGCCATGCGAAGGCGCTCGGCGCGACGGACGCCGCCACCGAAATCTCCGAAGGCGACGGCCTGTCGGTGTCGGTGCGCC
GCGGCGAGGTCGAGACGATCGAACACAACCGCGACAAGATGGTCGGCGTGACGGTGTTCATCGGCAAGAAGCGCGGCAAC
GCGAGCACGTCGGACTTCTCGCCGGCCGCGATCAAGGATACCGTCGCTGCCGCGTACAACATCGCGCGCTTCACGGCAGA
GGACGACGCGGCCGGCCTCGCCGAGGCCGAGCTGCTCGAAACCGACCCGCGCGACCTCGACCTGTATCACCCGTGGGCGC
TGTCGGCCGACGAGGCCGTCGAGCTCGCCCGCCGCGCGGAAGACGCCGCGTTCGCGGTCAGCCCGCAGATCCGCAACTCG
GAAGGCGCGAGCGTGTCGGCGCAGCATTCGCAGTTCGTGCTCGCGACGTCGCGCGGCTTCCTCGCCGGCTATCCGTACTC
GCGCCACTACATCGCATGCGCGCCGATCGCGGGCAGCGGTCGCCACATGCAGCGCGACGACTGGTATTCGTCGAAGCGCA
GCGCGGTCGATCTCGCGGCGCCGGAAGCCGTCGGGCGCTATGCGGCCGAGCGTGCGCTCGCGCGGATGGGCGCGCGCCGT
CTCGACACCCGCAAGGTGCCCGTGCTGTTCGAGGCGCCGCTCGCGGCCGGCCTGCTCGGCGCGTTCGTGCAGGCCGTCAG
CGGCGGCGCGCTGTACCGCAAGACGTCGTTCCTCGTCGACAGCCTCGGCAAGCCGGTGTTCGCACCGCACGTCCAGGTCG
TCGAGGATCCGCACGTGCCGCGCGCGATGGGCAGCGCGCCGTTCGACGAGGAGGGCGTGCGCACGCGTGCGCGCAGCGTC
GTCAAGGACGGCGTCGTCGAAGGCTACTTCCTGTCGACCTATTCGGCACGCAAGCTCGGCACGCAGACGACCGGTAACGC
CGGCGGCTCGCACAACCTCGCGCTGCGCAGCTCGGACACGCAGCCGGGCGACGACTTCGACGCAATGCTGAAGAAGCTCG
GCACGGGCCTGCTGCTGACCGAGCTGATGGGGCAGGGCGTGAACTACGTGACCGGCGACTATTCGCGCGGTGCGGCGGGC
TTCTGGGTCGAGAACGGCGTGATCCAGTATCCGGTCGAGGAAATCACCGTCGCGAGCACGCTGCAGGAGATGTTCCGGCA
TATCGTCGCGATCGGCGCGGATTCGATCGTGCGCGGGACGAAGGAAACGGGCTCGGTGCTGATCGAGCAGATGACGATCG
CCGGGCAGTAA

Upstream 100 bases:

>100_bases
CAAGCTTGTCTGTGCCCGGCGCCGGACCTTGCTATGATCGCGGGATACGTAACATTTTGACCATGCGGGCGCCCGCCCGC
CACCGGATACCAAGACGACG

Downstream 100 bases:

>100_bases
GCGGCGCGGCATCGGCCGCCAGGAAACGCAAAAGCCCGACCGGCGCGAGTGAGCCGGTCGGGCTTTTTTACGCGTGCCGC
GTGTCGGTCAGTCGCGCTTG

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKMVGVTVFIGKKRGN
ASTSDFSPAAIKDTVAAAYNIARFTAEDDAAGLAEAELLETDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNS
EGASVSAQHSQFVLATSRGFLAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAVDLAAPEAVGRYAAERALARMGARR
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHVQVVEDPHVPRAMGSAPFDEEGVRTRARSV
VKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSDTQPGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAG
FWVENGVIQYPVEEITVASTLQEMFRHIVAIGADSIVRGTKETGSVLIEQMTIAGQ

Sequences:

>Translated_456_residues
MAANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKMVGVTVFIGKKRGN
ASTSDFSPAAIKDTVAAAYNIARFTAEDDAAGLAEAELLETDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNS
EGASVSAQHSQFVLATSRGFLAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAVDLAAPEAVGRYAAERALARMGARR
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHVQVVEDPHVPRAMGSAPFDEEGVRTRARSV
VKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSDTQPGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAG
FWVENGVIQYPVEEITVASTLQEMFRHIVAIGADSIVRGTKETGSVLIEQMTIAGQ
>Mature_455_residues
AANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETIEHNRDKMVGVTVFIGKKRGNA
STSDFSPAAIKDTVAAAYNIARFTAEDDAAGLAEAELLETDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNSE
GASVSAQHSQFVLATSRGFLAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAVDLAAPEAVGRYAAERALARMGARRL
DTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHVQVVEDPHVPRAMGSAPFDEEGVRTRARSVV
KDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSDTQPGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGF
WVENGVIQYPVEEITVASTLQEMFRHIVAIGADSIVRGTKETGSVLIEQMTIAGQ

Specific function: May facilitate the secretion of the peptide antibiotic microcin B17 (MccB17) by completing its maturation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=439, Percent_Identity=48.0637813211845, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48836; Mature: 48705

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETI
CCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHH
EHNRDKMVGVTVFIGKKRGNASTSDFSPAAIKDTVAAAYNIARFTAEDDAAGLAEAELLE
HCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
TDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATSRGF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCEEEEEECCCC
LAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAVDLAAPEAVGRYAAERALARMGARR
EECCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHVQVVEDPHVP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCC
RAMGSAPFDEEGVRTRARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSDT
HHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEECCCC
QPGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGVIQYPVEEITVAST
CCCCCHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCEEECCHHHHHHHHH
LQEMFRHIVAIGADSIVRGTKETGSVLIEQMTIAGQ
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AANLDVQARYFPHTQDQLKEIASDILRHAKALGATDAATEISEGDGLSVSVRRGEVETI
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEECCCCHHH
EHNRDKMVGVTVFIGKKRGNASTSDFSPAAIKDTVAAAYNIARFTAEDDAAGLAEAELLE
HCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
TDPRDLDLYHPWALSADEAVELARRAEDAAFAVSPQIRNSEGASVSAQHSQFVLATSRGF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCEEEEEECCCC
LAGYPYSRHYIACAPIAGSGRHMQRDDWYSSKRSAVDLAAPEAVGRYAAERALARMGARR
EECCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LDTRKVPVLFEAPLAAGLLGAFVQAVSGGALYRKTSFLVDSLGKPVFAPHVQVVEDPHVP
CCCCCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCCCC
RAMGSAPFDEEGVRTRARSVVKDGVVEGYFLSTYSARKLGTQTTGNAGGSHNLALRSSDT
HHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCCCCEEEECCCC
QPGDDFDAMLKKLGTGLLLTELMGQGVNYVTGDYSRGAAGFWVENGVIQYPVEEITVAST
CCCCCHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCEEEECCEEECCHHHHHHHHH
LQEMFRHIVAIGADSIVRGTKETGSVLIEQMTIAGQ
HHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]