| Definition | Burkholderia ambifaria AMMD chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008390 |
| Length | 3,556,545 |
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The map label for this gene is gyrA [H]
Identifier: 115350970
GI number: 115350970
Start: 1006639
End: 1009242
Strand: Direct
Name: gyrA [H]
Synonym: Bamb_0916
Alternate gene names: 115350970
Gene position: 1006639-1009242 (Clockwise)
Preceding gene: 115350963
Following gene: 115350971
Centisome position: 28.3
GC content: 64.48
Gene sequence:
>2604_bases ATGGATCAATTCGCCAAAGAGACCCTGCCCACCTCCCTTGAGGAGGAAATGCGCCGTTCGTATCTCGATTACGCGATGAG CGTGATCGTCGGACGTGCCCTTCCGGATGTCCGCGATGGCCTGAAGCCCGTGCACCGGCGCGTACTGTTCGCGATGCACG AACTGAACAACGACTGGAACCGCGCGTACAAGAAATCGGCGCGTATCGTCGGTGACGTGATCGGTAAGTATCACCCGCAC GGCGATACCGCGGTGTACGACACGATCGTCCGGATGGCGCAGGACTTCTCGCTGCGCTACATGCTGATCGACGGGCAGGG CAACTTCGGCTCGATCGACGGCGACAATGCCGCGGCGATGCGTTACACCGAAATTCGCATGGCGAAGATCGGTCACGAGC TGCTCGCCGACATCGACAAGGAAACGGTCGACTTCGAGCCGAACTACGACGGCAACGAAATGCAGCCGGCGGTCCTGCCG TCGCGCATTCCGAACCTGCTGATCAACGGCTCGTCGGGCATCGCGGTCGGCATGGCGACCAACATCCCGCCGCACAACCT GAACGAAGTCGTCGACGCTTGTCAGCACCTGCTGAACAACTCCGAAGCGACGATCGACGAGCTGATCGAGATCATCCCGG CCCCGGACTTCCCGACGGCCGGCATCATCTACGGCGTCGCCGGCGTGCGCGACGGCTATCGCACCGGCCGTGGCCGCGTC GTGATGCGCGCCACCACGCACTTCGAGGAGATCGACCGCGGCCAGCGGATGGCGATCATCGTCGACGAGCTGCCGTACCA GGTGAACAAGCGCTCGCTGCTCGAGCGGATCGCCGAGCTCGTCAACGAGAAGAAGCTCGAGGGCATCTCCGACATCCGCG ACGAGTCCGACAAGAGCGGCATGCGTGTCGTGATCGAGCTCAAGCGCGGCGAAGTGCCGGAAGTGGTGCTGAACAACCTG TACAAGGCGACGCAGCTGCAGGACACGTTCGGCATGAACATGGTCGCGCTGGTCGACGGCCAGCCGAAGCTGCTGAACCT GAAGGAAATCCTGCAGTGCTTCCTGTCGCACCGACGCGAAGTGCTGACGCGCCGCACGATCTACGAACTGCGCAAGGCCC GCGAACGCGGCCACGTGCTCGAAGGTCTCGCGGTCGCGCTCGCGAACATCGACGAGTTCATCGCGATCATCAAGGCCGCG CCGACGCCGCCGATCGCGAAGCAGGAGCTGATGGCGAAGCCGTGGGATTCGTCGCTCGTGCGCGAGATGCTCACGCGCGC CGAGACCGAGAACGCATCGGCGGGCGGCCGCTCCGCGTATCGTCCGGAAGGCCTGAACCCCGCGTTCGGGATGCAGACCG ACGGGCTGTACCGTCTGTCCGACACGCAGGCGCAGGAAATCCTGCAGATGCGTCTGCAACGCCTGACCGGTCTCGAGCAG GACAAGATCATCGGCGAGTACCGCGAAGTGATGGCACAGATCGCCGACCTGCTGGACATCCTCGCGCGCCCGGAGCGGAT CACGACGATGATCGGCGACGAGCTGACGTCGGTGAAGGCCGAATTCGGCGACGCACGCCGCTCGCGCATCGAGCTGAACG CGACCGAACTGAATACGGAAGACCTGATCACGCCGCAGGACATGGTCGTCACGATGTCGCACGCGGGCTACGTGAAGTCG CAGCCGCTGTCCGAGTATCGCGCGCAGAAGCGCGGCGGTCGCGGCAAGCAGGCGACGCAGATGAAGGAAGACGACTGGAT CGAGACGCTGTTCATCGCGAACACGCACGATTACATCCTGTGCTTCTCGAACCGCGGCCGCGTGTACTGGGTCAAGGTCT ATGAAGTGCCGCAGGGCTCGCGCAACTCGCGCGGCCGCCCGATCGTCAACATGTTCCCGCTGCAGGAAGGCGAGAAGATC AACGTCGTGCTGCCGGTCAAGGAATTCTCGGCCGACAAGTTCGTGTTCATGGCGACGTCGCTCGGCACCGTGAAGAAGAC GCCGCTCGAGGCATTCAGCCGCCCGATGAAGAAGGGCATCATCGCGGTCGGCCTCGACGAGGGCGACTATCTGATCGGCG CGTCGATCACCGACGGCGCGCACGACGTGATGCTGTTCTCCGACTCCGGCAAGGCCGTGCGCTTCGACGAGAACGACGTG CGCCCGATGGGGCGCGAGGCGCGCGGCGTGCGCGGCATGCAGCTGGAGGACGGCCAGCAGGTCATCGCGCTGCTGGTCGC CGGCAGCGAGGAGCAGACCGTGCTCACCGCGACCGAGAACGGCTATGGCAAGCGCACGCCGATCGCCGAGTACACGCGTC ACGGCCGCGGCACGAAGGGGATGATCGCGATCCAGACGTCCGAGCGCAACGGCAAGGTCGTGGCCGCGACGCTCGTCGAC GCCGAGGATCAGATCATGCTGATCACGACCGCCGGCGTGTTGATTCGTACCCGCGTTTCCGAGATACGCGAGATGGGGCG CGCTACGCAAGGTGTTACACTCATCAGTCTCGATGAGGGTACCAAGCTCTCCGGCCTGCAGCAGGTCGCGGAAGCCGAAG AGGGCGAAGGCGAGGCCGACGAGGCGTCGGACGGCGAAGCCTGA
Upstream 100 bases:
>100_bases TGGCCGCCGATGGGCGCATGTTAGAATCTCGCGTTGCGTTGCGCATGCAGCGCCCACGCGAAAGGCGGTCGCCGTCTTCG CTCCGAAACGATACGGATAC
Downstream 100 bases:
>100_bases ATAACGGATGAGACTCGAGCCGCCGCGGGCGCCATGCGCCGCGGTCGGCGAGCAACCATTCATATTTCCAAAAGGGAGTG ATGATGCAAAAGCAATTCAA
Product: DNA gyrase subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 867; Mature: 867
Protein sequence:
>867_residues MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWNRAYKKSARIVGDVIGKYHPH GDTAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAMRYTEIRMAKIGHELLADIDKETVDFEPNYDGNEMQPAVLP SRIPNLLINGSSGIAVGMATNIPPHNLNEVVDACQHLLNNSEATIDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV VMRATTHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL YKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRREVLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAA PTPPIAKQELMAKPWDSSLVREMLTRAETENASAGGRSAYRPEGLNPAFGMQTDGLYRLSDTQAQEILQMRLQRLTGLEQ DKIIGEYREVMAQIADLLDILARPERITTMIGDELTSVKAEFGDARRSRIELNATELNTEDLITPQDMVVTMSHAGYVKS QPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYILCFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFPLQEGEKI NVVLPVKEFSADKFVFMATSLGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV RPMGREARGVRGMQLEDGQQVIALLVAGSEEQTVLTATENGYGKRTPIAEYTRHGRGTKGMIAIQTSERNGKVVAATLVD AEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEGTKLSGLQQVAEAEEGEGEADEASDGEA
Sequences:
>Translated_867_residues MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWNRAYKKSARIVGDVIGKYHPH GDTAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAMRYTEIRMAKIGHELLADIDKETVDFEPNYDGNEMQPAVLP SRIPNLLINGSSGIAVGMATNIPPHNLNEVVDACQHLLNNSEATIDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV VMRATTHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL YKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRREVLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAA PTPPIAKQELMAKPWDSSLVREMLTRAETENASAGGRSAYRPEGLNPAFGMQTDGLYRLSDTQAQEILQMRLQRLTGLEQ DKIIGEYREVMAQIADLLDILARPERITTMIGDELTSVKAEFGDARRSRIELNATELNTEDLITPQDMVVTMSHAGYVKS QPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYILCFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFPLQEGEKI NVVLPVKEFSADKFVFMATSLGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV RPMGREARGVRGMQLEDGQQVIALLVAGSEEQTVLTATENGYGKRTPIAEYTRHGRGTKGMIAIQTSERNGKVVAATLVD AEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEGTKLSGLQQVAEAEEGEGEADEASDGEA >Mature_867_residues MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWNRAYKKSARIVGDVIGKYHPH GDTAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAMRYTEIRMAKIGHELLADIDKETVDFEPNYDGNEMQPAVLP SRIPNLLINGSSGIAVGMATNIPPHNLNEVVDACQHLLNNSEATIDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV VMRATTHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSGMRVVIELKRGEVPEVVLNNL YKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRREVLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAA PTPPIAKQELMAKPWDSSLVREMLTRAETENASAGGRSAYRPEGLNPAFGMQTDGLYRLSDTQAQEILQMRLQRLTGLEQ DKIIGEYREVMAQIADLLDILARPERITTMIGDELTSVKAEFGDARRSRIELNATELNTEDLITPQDMVVTMSHAGYVKS QPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYILCFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFPLQEGEKI NVVLPVKEFSADKFVFMATSLGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV RPMGREARGVRGMQLEDGQQVIALLVAGSEEQTVLTATENGYGKRTPIAEYTRHGRGTKGMIAIQTSERNGKVVAATLVD AEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEGTKLSGLQQVAEAEEGEGEADEASDGEA
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=321, Percent_Identity=26.4797507788162, Blast_Score=95, Evalue=3e-19, Organism=Homo sapiens, GI19913408, Length=379, Percent_Identity=26.1213720316623, Blast_Score=94, Evalue=7e-19, Organism=Escherichia coli, GI1788562, Length=851, Percent_Identity=61.1045828437133, Blast_Score=1053, Evalue=0.0, Organism=Escherichia coli, GI1789396, Length=718, Percent_Identity=34.958217270195, Blast_Score=389, Evalue=1e-109, Organism=Caenorhabditis elegans, GI17535065, Length=494, Percent_Identity=26.1133603238866, Blast_Score=89, Evalue=1e-17, Organism=Caenorhabditis elegans, GI212645657, Length=379, Percent_Identity=26.1213720316623, Blast_Score=83, Evalue=6e-16, Organism=Caenorhabditis elegans, GI212645845, Length=172, Percent_Identity=31.9767441860465, Blast_Score=72, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=352, Percent_Identity=26.9886363636364, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI17136538, Length=349, Percent_Identity=26.647564469914, Blast_Score=94, Evalue=4e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 96389; Mature: 96389
Theoretical pI: Translated: 5.08; Mature: 5.08
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 3.8 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWN CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH RAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAM HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEE RYTEIRMAKIGHELLADIDKETVDFEPNYDGNEMQPAVLPSRIPNLLINGSSGIAVGMAT EHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCEEEEEEC NIPPHNLNEVVDACQHLLNNSEATIDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCE VMRATTHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSG EEEEHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC MRVVIELKRGEVPEVVLNNLYKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRRE CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHHHHHHHHHHHH VLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAAPTPPIAKQELMAKPWDSSLV HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHH REMLTRAETENASAGGRSAYRPEGLNPAFGMQTDGLYRLSDTQAQEILQMRLQRLTGLEQ HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCH DKIIGEYREVMAQIADLLDILARPERITTMIGDELTSVKAEFGDARRSRIELNATELNTE HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCEEEEEHEECCHH DLITPQDMVVTMSHAGYVKSQPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYIL HCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEE CFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFPLQEGEKINVVLPVKEFSADKFVFMATS EECCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHCCCCCEEEEEEC LGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV CCCCCCCCHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCCEEEEECCCCCEEEECCCCC RPMGREARGVRGMQLEDGQQVIALLVAGSEEQTVLTATENGYGKRTPIAEYTRHGRGTKG CCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHCCCCCCC MIAIQTSERNGKVVAATLVDAEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEG EEEEEECCCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCHHCCEEEEEECCC TKLSGLQQVAEAEEGEGEADEASDGEA CCHHHHHHHHHHHCCCCCCCCCCCCCC >Mature Secondary Structure MDQFAKETLPTSLEEEMRRSYLDYAMSVIVGRALPDVRDGLKPVHRRVLFAMHELNNDWN CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH RAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQDFSLRYMLIDGQGNFGSIDGDNAAAM HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCEE RYTEIRMAKIGHELLADIDKETVDFEPNYDGNEMQPAVLPSRIPNLLINGSSGIAVGMAT EHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECCCCEEEEEEC NIPPHNLNEVVDACQHLLNNSEATIDELIEIIPAPDFPTAGIIYGVAGVRDGYRTGRGRV CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCE VMRATTHFEEIDRGQRMAIIVDELPYQVNKRSLLERIAELVNEKKLEGISDIRDESDKSG EEEEHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC MRVVIELKRGEVPEVVLNNLYKATQLQDTFGMNMVALVDGQPKLLNLKEILQCFLSHRRE CEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHHHHHHHHHHHH VLTRRTIYELRKARERGHVLEGLAVALANIDEFIAIIKAAPTPPIAKQELMAKPWDSSLV HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHHH REMLTRAETENASAGGRSAYRPEGLNPAFGMQTDGLYRLSDTQAQEILQMRLQRLTGLEQ HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCH DKIIGEYREVMAQIADLLDILARPERITTMIGDELTSVKAEFGDARRSRIELNATELNTE HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHCEEEEEHEECCHH DLITPQDMVVTMSHAGYVKSQPLSEYRAQKRGGRGKQATQMKEDDWIETLFIANTHDYIL HCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEE CFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFPLQEGEKINVVLPVKEFSADKFVFMATS EECCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEEEHHHCCCCCEEEEEEC LGTVKKTPLEAFSRPMKKGIIAVGLDEGDYLIGASITDGAHDVMLFSDSGKAVRFDENDV CCCCCCCCHHHHHHHHHCCEEEEEECCCCEEEEEEECCCCCEEEEECCCCCEEEECCCCC RPMGREARGVRGMQLEDGQQVIALLVAGSEEQTVLTATENGYGKRTPIAEYTRHGRGTKG CCCCHHHCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHCCCCCCC MIAIQTSERNGKVVAATLVDAEDQIMLITTAGVLIRTRVSEIREMGRATQGVTLISLDEG EEEEEECCCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHCCHHCCEEEEEECCC TKLSGLQQVAEAEEGEGEADEASDGEA CCHHHHHHHHHHHCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7811002; 10984043 [H]