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The map label for this gene is hrcA

Identifier: 115350693

GI number: 115350693

Start: 721807

End: 722829

Strand: Direct

Name: hrcA

Synonym: Bamb_0639

Alternate gene names: 115350693

Gene position: 721807-722829 (Clockwise)

Preceding gene: 115350690

Following gene: 115350694

Centisome position: 20.3

GC content: 66.08

Gene sequence:

>1023_bases
ATGCTAGATCCTCGCGCACGAACCCTCCTGAAAACCCTGATCGAACGGTATATCGCCGACGGTCAGCCGGTCGGATCGCG
CACGTTGTCCCGTTACTCCGGGCTCGAGTTGAGCCCGGCAACGATCCGCAACGTGATGTCCGACCTGGAGGAGCTCGGCC
TTGTGTCGAGCCCCCACACATCGGCCGGCCGCGTGCCGACGCCGCGCGGCTATCGCCTGTTCGTCGACACGATGCTGACG
GTCGAGACGCCGATCGACGCCGAGGCCGTCGCGCGGCAAGTGCAGCACACGCTCCAGGCCGGCGAACCGCAGCAGCGGGT
GGTGGCGGCCGCCGCGAGCGTGCTGTCGAACCTGTCGCAGTTCGCGGGCGTCGTGCTGACGCCGCGCCGCAGCCACGTGT
TCAAGCAGATCGAGTTCATGCGCCTGTCGGACAAGCGGATCCTGCTGATCATCGTCACGCCCGAGGGCGACGTGCAGAAC
CGGATGCTCGCGACGCCGCGCGACTATTCGCCGTCGCAGCTGACCGAGGCATCCAACTACATCAACGCGCATTTCGCCGG
GCTGTCGTTCGACGAGGTGCGCCGCCGCCTGCGCGACGAGATCGACCAGTTGCGCGGCGACATGACCACGCTGATGCATG
CGGCCGTGACGGCCAGCACCGAGGTGCCCGATACCGAGGACACCGTGCTCATTTCCGGCGAGCGCAACCTGCTCGAAGTG
GCGGATCTGTCGTCCGACATGGCACGGCTGCGCAAGTTGTTCGACGTGTTCGACCAAAAGACGGGCCTCCTGCAACTGCT
CGACGTGTCGAGCCACGCCCAGGGCGTGCAGATCTTCATCGGCGGCGAATCGACGCTCGTGCCGATCGAGGAGATGAGCG
TCGTCACCGCACCCTACGAGGTGAACGGCCAGATCGTCGGCACGCTCGGCGTGATCGGCCCGACCCGCATGGCTTACAAC
CGCGTGATCCCGATCGTCGACATCACCGCGCGCCTGCTGTCGCTTACGCTGAGCCAGCAATAA

Upstream 100 bases:

>100_bases
AAGAACCGGTTGTGCGCAGACGGGGCCGGATCGGCCGGCCCGCGCGACTGGGGCCGCTGCCACTCGCCGTGCTGGCGCGG
TTGCGCTAAAATTTTCCACC

Downstream 100 bases:

>100_bases
CCTGACCGGCACCGTCCCGCCATCGTGCCGCGGCGGCGCGCGCGCCGCCATTCGGCCGAACGGCCAGCCGACCCGAGCGG
GGCGGCCCGCTATAATTGAG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLT
VETPIDAEAVARQVQHTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQN
RMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYN
RVIPIVDITARLLSLTLSQQ

Sequences:

>Translated_340_residues
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLT
VETPIDAEAVARQVQHTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQN
RMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYN
RVIPIVDITARLLSLTLSQQ
>Mature_340_residues
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLT
VETPIDAEAVARQVQHTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQN
RMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYN
RVIPIVDITARLLSLTLSQQ

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_BURA4 (B1YTJ4)

Other databases:

- EMBL:   CP001025
- RefSeq:   YP_001807375.1
- ProteinModelPortal:   B1YTJ4
- SMR:   B1YTJ4
- GeneID:   6177157
- GenomeReviews:   CP001025_GR
- KEGG:   bac:BamMC406_0663
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- BioCyc:   BAMB398577:BAMMC406_0663-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 37420; Mature: 37420

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRVPTPRGYRLFVDTMLTVETPIDAEAVARQVQHTLQAGEPQQRVVAAAASVLSNLSQ
CCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRMLATPRDYSPSQLTEASNY
HCCEEECCHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHH
INAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYE
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHCEEEECCEE
VNGQIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
ECCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRVPTPRGYRLFVDTMLTVETPIDAEAVARQVQHTLQAGEPQQRVVAAAASVLSNLSQ
CCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRMLATPRDYSPSQLTEASNY
HCCEEECCHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHH
INAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYE
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHCEEEECCEE
VNGQIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
ECCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA