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The map label for this gene is tkt1 [H]

Identifier: 115350592

GI number: 115350592

Start: 603192

End: 605264

Strand: Direct

Name: tkt1 [H]

Synonym: Bamb_0538

Alternate gene names: 115350592

Gene position: 603192-605264 (Clockwise)

Preceding gene: 115350588

Following gene: 115350593

Centisome position: 16.96

GC content: 66.62

Gene sequence:

>2073_bases
ATGCCGCCGTGCCCCCGTTTCCTCGACTCGTTCTCCGGACTCGACATGACGACTTCGTCTCCCGCCTCTACCACTCTGAT
GGCCAACGCGATCCGTGCGCTCGCGATGGACGCCGTCCAGCAAGCGAACTCCGGCCACCCCGGCATGCCGATGGGCATGG
CCGAAATCGGCGTTGCACTCTGGTCGCGCCACCTGAAGCACAACCCGACGAACCCGCACTGGGCAGACCGCGACCGTTTC
GTGCTGTCGAACGGCCATGGCTCGATGCTGCTGTACTCGCTGCTGCACCTGACCGGCTACGACCTGCCGATCGAAGAGCT
GAAGAACTTCCGCCAACTGCACTCGAAGACGCCGGGCCACCCGGAATATGGCATCACGCCGGGCGTCGAGACGACCACCG
GCCCGCTCGGCCAGGGTCTCGCGAACGCGGTCGGCATGGCGCTGGGCGAAGCGTTGATGGCCGACGAGTTCAACCGTGAC
GGCGCGAAGATCGTCGATCACCACACGTACGTGTTCCTCGGCGACGGCTGCCTGATGGAAGGCATCTCGCACGAAGCCTG
CTCGCTCGCGGGCACGCTGAAGCTGAACAAGCTGATCGCGCTGTACGACGACAACGGCATCTCGATCGACGGCGACGTCG
TCAACTGGTTCCACGACGACACGCCGAAGCGCTTCGAGGCATACGGCTGGAACGTGATCCCGAACGTGAACGGCCACGAC
GTCGACGCGGTCGACGCGGCCATCGCGAAGGCGAAGCTGTCGGACAAGCCGACGATGATCTGCTGCAAGACGGTGATCGG
CAAGGGCGCGGCGACCAAGGCCGGCGGCCACGACGTGCACGGCGCGGCGCTCGGCGCGGAAGAAATCGCGAAGACGCGCG
AAGCGCTCGGCTGGAAGTGGGAGCCGTTCGTGATTCCGCAGGAAGTCTATGCGGCCTGGGACGCGAAGGAAGCCGGCAAG
CGTGCCGAGACCGAATGGGATGCGACGTTAGCGCAATATCGCGAGAAATTCCCCGCGCAAGCCGCTGAATTCGAGCGCCG
GATGGCCAACCAGCTGCCGGCCGACTGGGCCGAGAAGGCCGCGGCGATCATCGCCGGCGCGAACGAGCGCGCCGAGACGG
TCGCGACCCGCAAGGCTTCGCAGCAGGCCATCGAAGGGCTCGCCGCCGCACTGCCGGAACTGCTCGGCGGCTCGGCCGAC
CTGACCGGCTCGAACCTGACCAACTGGAAGGCATCGAAGGCGGTGCGCGCGAATCCGGAAGGCGCGGGCGTGCTGCTCGG
CAACCACATCAACTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGCTCAACGGCCTCGCGCTGCACGGCGGCCACAAGC
CGTTCGGCGGCACGTTCCTGACGTTCTCCGACTACAGCCGCAACGCGCTGCGCGTCGCGGCGCTGATGAAGGTCCCGACG
ATCTTCGTGTTCACGCACGATTCGATCGGCCTCGGCGAAGACGGCCCGACGCACCAGTCGATCGAGCACGTGTCGAGCCT
GCGCCTGATCCCGAACCTCGACGTGTGGCGTCCGGCCGACACGGTCGAGACGGCCGTCGCATGGACTCACGCGGTTGCCG
CCGACCGTCCGTCGAGCCTGATCTTCAGCCGTCAGAACCTCGCGTTCAACCCGCGTACCGATGCGCAGATCGCGAACATC
GAGAAGGGCGGCTACGTGCTGAAGGACTGGGACGAAGAGATCGTCGCGCGCAAGATCATCCTGATCGCGACGGGCTCGGA
AGTCGAGCTCGCGATGAAGGCCGTCGAGCCGCTCGCGCAGCAGGGCATCGCGGCCCGCGTCGTGTCGATGCCGTCGACCA
ACGTGTTCGATCGCCAGGACGCCGAATACCGCGAACGCGTGCTGCCGCACGGCGTGCGCCGCGTCGCGATCGAAGCGGGC
GTGACGAGCTTCTGGCACAAGTATGTCGGCCTCGAAGGCGGCGTCGTCGGGATCGACACGTTCGGCGAATCGGCACCGGC
CGGCGTGCTGTTCAAGTACTTCGGCTTCACCGTCGAGCACGTCGTCGAGACCGCGAAGGCCGTGCTGGCCTAA

Upstream 100 bases:

>100_bases
AAAATGACGAGCTTTGCAGCCCCGTCCGTAGGCTCCGTCCGCTTCGCGTCCGTCAGGCGCCGCACCGCGCGCCGGGAACG
ATTGACGCTCGAGCTTCCGG

Downstream 100 bases:

>100_bases
AAGCATACGCGACGCGCGCCACCCGTCGCGCGCGTCGCACCGTGAAGCTGCACGTAACTAATTTTTTTCAGCCATCAGGA
GATAGACCATGACGATCCGC

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRD
GAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKLSDKPTMICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGK
RAETEWDATLAQYREKFPAQAAEFERRMANQLPADWAEKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSAD
LTGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAALNGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPT
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNLDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAG
VTSFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA

Sequences:

>Translated_690_residues
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRF
VLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRD
GAKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
VDAVDAAIAKAKLSDKPTMICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGK
RAETEWDATLAQYREKFPAQAAEFERRMANQLPADWAEKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSAD
LTGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAALNGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPT
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNLDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANI
EKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAG
VTSFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA
>Mature_689_residues
PPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPTNPHWADRDRFV
LSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDG
AKIVDHHTYVFLGDGCLMEGISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHDV
DAVDAAIAKAKLSDKPTMICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKWEPFVIPQEVYAAWDAKEAGKR
AETEWDATLAQYREKFPAQAAEFERRMANQLPADWAEKAAAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADL
TGSNLTNWKASKAVRANPEGAGVLLGNHINYGVREFGMSAALNGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPTI
FVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNLDVWRPADTVETAVAWTHAVAADRPSSLIFSRQNLAFNPRTDAQIANIE
KGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGV
TSFWHKYVGLEGGVVGIDTFGESAPAGVLFKYFGFTVEHVVETAKAVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=607, Percent_Identity=28.006589785832, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI4507521, Length=607, Percent_Identity=28.006589785832, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI133778974, Length=589, Percent_Identity=25.9762308998302, Blast_Score=139, Evalue=1e-32,
Organism=Escherichia coli, GI48994911, Length=671, Percent_Identity=62.5931445603577, Blast_Score=861, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=60.0600600600601, Blast_Score=808, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=686, Percent_Identity=26.8221574344023, Blast_Score=165, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=673, Percent_Identity=49.62852897474, Blast_Score=617, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319593, Length=675, Percent_Identity=45.4814814814815, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI45551847, Length=715, Percent_Identity=24.8951048951049, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI45550715, Length=715, Percent_Identity=24.8951048951049, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24666278, Length=679, Percent_Identity=25.1840942562592, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24645119, Length=666, Percent_Identity=24.6246246246246, Blast_Score=139, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74303; Mature: 74172

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAVDAAIAKAKLSDKPTMICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKW
CHHHHHHHHHHHCCCCCHHEEHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCC
EPFVIPQEVYAAWDAKEAGKRAETEWDATLAQYREKFPAQAAEFERRMANQLPADWAEKA
CCEECHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
AAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GAGVLLGNHINYGVREFGMSAALNGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPT
CCEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNLDVWRPADTVETAVAWTHAVAADRPSSL
EEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTSFWHKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVEHVVETAKAVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PPCPRFLDSFSGLDMTTSSPASTTLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVAL
CCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
WSRHLKHNPTNPHWADRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGH
HHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PEYGITPGVETTTGPLGQGLANAVGMALGEALMADEFNRDGAKIVDHHTYVFLGDGCLME
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHH
GISHEACSLAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPNVNGHD
CCCHHHHHHHHHEEEEEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCC
VDAVDAAIAKAKLSDKPTMICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTREALGWKW
CHHHHHHHHHHHCCCCCHHEEHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCC
EPFVIPQEVYAAWDAKEAGKRAETEWDATLAQYREKFPAQAAEFERRMANQLPADWAEKA
CCEECHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
AAIIAGANERAETVATRKASQQAIEGLAAALPELLGGSADLTGSNLTNWKASKAVRANPE
HEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
GAGVLLGNHINYGVREFGMSAALNGLALHGGHKPFGGTFLTFSDYSRNALRVAALMKVPT
CCEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCE
IFVFTHDSIGLGEDGPTHQSIEHVSSLRLIPNLDVWRPADTVETAVAWTHAVAADRPSSL
EEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
IFSRQNLAFNPRTDAQIANIEKGGYVLKDWDEEIVARKIILIATGSEVELAMKAVEPLAQ
EEECCCCCCCCCCCCEEEEECCCCEEEECCHHHHHHCEEEEEEECCHHHHHHHHHHHHHH
QGIAARVVSMPSTNVFDRQDAEYRERVLPHGVRRVAIEAGVTSFWHKYVGLEGGVVGIDT
CCHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
FGESAPAGVLFKYFGFTVEHVVETAKAVLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA