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The map label for this gene is uxuR [H]

Identifier: 116249337

GI number: 116249337

Start: 725750

End: 726499

Strand: Reverse

Name: uxuR [H]

Synonym: pRL120674

Alternate gene names: 116249337

Gene position: 726499-725750 (Counterclockwise)

Preceding gene: 116249340

Following gene: 116249336

Centisome position: 83.5

GC content: 62.53

Gene sequence:

>750_bases
ATGCGGGGGTCAGGCGTGGCTATGCAGATGAAGGATCGCAGCAAAGGCTCCGGGTCGCTGGTCTCACAGGTCGGCGAAAG
CCTCCGGCAAGCCATATTGAGCGGCCAGTATTCTGCCGGTGACAAGCTTCCGAGTGAACACGAGTTGACCGAAACGCACA
GCGTCAGCCGAACCGTCGTGCGCGAGGCAGTGGCAGCGCTTCGCTCCGACGGGCTTGTCGAGGTGCGCCAGGGAGCGGGG
ATTTTCGTACTCGGTGCCGATCCGGCGCTCTCCGCGCGGAAAGTCGACAAGGCCCGCGTCGCCTCCGATCTTGAGGTCCT
CGAGATCAGAACACCTGTCGAAATCGAGGCGGCGGGCCTAGCGGCCCTACGCCGCTCGCCGGCACAGGAGGAAGCGATAT
TCGAATGTCACCGGAAAATCCTCCAATGCATCGAGAGCGATCAATCCATTCGCGATGCGGATCTCGAGCTCCATGCCGCG
ATCGCGGAGGCCACGAACAATCCGCTGTTCAGGCAGTTCCTGGAATCGCAGGGCTCTGCGATCATCCCGCAGTCGAGGCT
CGTCCCGGAATCGAGGACGGCCGAACAGACCGCCTATCGAAAGCTGATCCACAGGGAGCACGAGGCAATCGTCGTCGCCA
TCTCAGACAGAGACGACCAGGCCGCCCGCAACGCCATGCGCGACCATCTGGTCGGCAGCCAGGCCAGGTACCGCAACCTG
CTGAGGGATCTGCGAAGCTTTACGAGTTGA

Upstream 100 bases:

>100_bases
CCGCTCGTCCATTGAAAGATGGAGAAATTTGTCATACATGTGTGATGAATCGTGAATTTCGCAATGCCGCGCGTTTGAAC
GGGCGTGCGGATCAAAGCCG

Downstream 100 bases:

>100_bases
CATCCGATCCGGAATTGCGTGGAAGCCGGACTGATTATGTGCGCACGGCCGGCAGGCGCCGGATGTGGCTCGAGGCTCTT
GGCGCAAGGCCGCTCCTGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRGSGVAMQMKDRSKGSGSLVSQVGESLRQAILSGQYSAGDKLPSEHELTETHSVSRTVVREAVAALRSDGLVEVRQGAG
IFVLGADPALSARKVDKARVASDLEVLEIRTPVEIEAAGLAALRRSPAQEEAIFECHRKILQCIESDQSIRDADLELHAA
IAEATNNPLFRQFLESQGSAIIPQSRLVPESRTAEQTAYRKLIHREHEAIVVAISDRDDQAARNAMRDHLVGSQARYRNL
LRDLRSFTS

Sequences:

>Translated_249_residues
MRGSGVAMQMKDRSKGSGSLVSQVGESLRQAILSGQYSAGDKLPSEHELTETHSVSRTVVREAVAALRSDGLVEVRQGAG
IFVLGADPALSARKVDKARVASDLEVLEIRTPVEIEAAGLAALRRSPAQEEAIFECHRKILQCIESDQSIRDADLELHAA
IAEATNNPLFRQFLESQGSAIIPQSRLVPESRTAEQTAYRKLIHREHEAIVVAISDRDDQAARNAMRDHLVGSQARYRNL
LRDLRSFTS
>Mature_249_residues
MRGSGVAMQMKDRSKGSGSLVSQVGESLRQAILSGQYSAGDKLPSEHELTETHSVSRTVVREAVAALRSDGLVEVRQGAG
IFVLGADPALSARKVDKARVASDLEVLEIRTPVEIEAAGLAALRRSPAQEEAIFECHRKILQCIESDQSIRDADLELHAA
IAEATNNPLFRQFLESQGSAIIPQSRLVPESRTAEQTAYRKLIHREHEAIVVAISDRDDQAARNAMRDHLVGSQARYRNL
LRDLRSFTS

Specific function: Repressor for the uxuRBA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=230, Percent_Identity=36.0869565217391, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI87082208, Length=239, Percent_Identity=29.7071129707113, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790032, Length=228, Percent_Identity=32.4561403508772, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1789353, Length=231, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27289; Mature: 27289

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGSGVAMQMKDRSKGSGSLVSQVGESLRQAILSGQYSAGDKLPSEHELTETHSVSRTVV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
REAVAALRSDGLVEVRQGAGIFVLGADPALSARKVDKARVASDLEVLEIRTPVEIEAAGL
HHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCHHEEECCCCEEHHHHH
AALRRSPAQEEAIFECHRKILQCIESDQSIRDADLELHAAIAEATNNPLFRQFLESQGSA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCE
IIPQSRLVPESRTAEQTAYRKLIHREHEAIVVAISDRDDQAARNAMRDHLVGSQARYRNL
ECCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHH
LRDLRSFTS
HHHHHHHCC
>Mature Secondary Structure
MRGSGVAMQMKDRSKGSGSLVSQVGESLRQAILSGQYSAGDKLPSEHELTETHSVSRTVV
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
REAVAALRSDGLVEVRQGAGIFVLGADPALSARKVDKARVASDLEVLEIRTPVEIEAAGL
HHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHCCCHHEEECCCCEEHHHHH
AALRRSPAQEEAIFECHRKILQCIESDQSIRDADLELHAAIAEATNNPLFRQFLESQGSA
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCE
IIPQSRLVPESRTAEQTAYRKLIHREHEAIVVAISDRDDQAARNAMRDHLVGSQARYRNL
ECCHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHH
LRDLRSFTS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]