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The map label for this gene is qseC [H]

Identifier: 116249331

GI number: 116249331

Start: 719348

End: 720724

Strand: Direct

Name: qseC [H]

Synonym: pRL120668

Alternate gene names: 116249331

Gene position: 719348-720724 (Clockwise)

Preceding gene: 116249330

Following gene: 116249338

Centisome position: 82.68

GC content: 64.49

Gene sequence:

>1377_bases
GTGGGCGCGACGATCGCGCGGCTCAGCCAGAGCCTGAGGGTGCAGCTGCTCTGCTGGGTGCTGCTGACCCTGTTAGGGGC
GATCGGCTTCAATCTTTACGACAGCTTCTGGACGGCTGACGCCACAGCAAAGCTGGTGACGGATCGAACACTTCTGGCAT
CGGCCCGCGTCATTGCCGAAGCCGTCCGCGTCGATGAGGGCGGCAACGTTCAGGTGGACGTACCGCCTTCCGCGCTGGAG
ATGTTTGATACGGGCTTCGGCGACGGGGTGTCTTATCAGGTCATCACCGCATGGGGCAGTCTGGTCAGCGGCTTTCCCGA
CCTGCCGTTGCCGGCCGTCCAGCGGACCGGTGAGGATCGTGCGTTCCACGGTGCCGATGTGCGCGTCCTGATGCTCGATC
ATCCCGTCGTCGGCCTTCCCGATGACGGCGCGATCTCCGTCACCGTCGCCGTTACGCATAACAGCCAGTATGCGATGCGA
AGGCAATTGTGGCTCTCGGACTTTTCGAAGCAGTTCGTGCTCGTCTTCGTCGCAAGCCTGGTGACCATCCTTGGGCTCCA
ACGGGGCCTGGCCCCTGCGCTGAGACTGCGGGACGCTCTGCGCCAGCGCGGGCGCAACCGTCTCGATCCGCTGCCGCCGG
AGATGGTACAGAGCGAACTGCAGCCGCTCGTTCACGCCCTGAACGACTACATGGAGCGCGTCCAGAACCAGATGGCCGCG
CAGCGACGGTTCGTATCGAATGCTGCGCATCAACTGCGAACCCCCCTGGCGCTAATTTCGACCCAGGCGAGCGTGGCGGC
CCGCGAAGCCGATGCAGCTCGCCGCGACGAGGCGCTTTTCGCCCTTCGCACCAGCACGAAGCAGATTTCGCGTCTCGCCA
GCCAGCTACTTACCTTGTCGCGGGCCGAGCCCGGAAGTCGGCGCCCGCGCAGCGATGCGACCGACCTTACGAAGGCTGCC
CGCGAGATCCTGGAATCGCATGCCGAAGAGGCGCTCAAGCGCAACATCGACGTCGGCCTGGAAGCAGTGCGCCCTGTCAT
TGTCGACGGCGACGCGACGATGTTGCGCGAGATGTTGGTCAACCTCATAGACAATGCGATCCGCTATACCCGCCCGAATG
GACGGGTGACCGTCGCCGTCGGGCAGGCGGACGGCAACGCCGTGGTGACCGTCGAGGACAACGGGCCGGGTATTCCAAGC
GGGGAGCGTGAGCAGGTTTTCGAACGATTCTACCGGGTCATAGGGATCGAAGGCGAGGGGAGCGGTCTGGGACTTGCGAT
CGTTCGGGAGGTTGTCGAAGGCGCTGGAGGTTCAGTCTCGCTCGAAGATGCGGAAGGCGGTGGGCTCGTCGTGACGGTGC
GGCTGCCGCTCGCTTAG

Upstream 100 bases:

>100_bases
CACCGGCTGCGAAAGAAACTCGAGAGCAGTTCGGTTCAAATTGCCACGTTGCGCGGACTTGGTTATCTCCTCAGACATGT
CCAATAGCCTCGTCACCAAG

Downstream 100 bases:

>100_bases
ACCTAAGTGCATCAAGTGAAAAGAAGGCCGGGCATGCACCCGGCCTTCTGTTCGATCCACCTTGGGAGGAGGTCGATTGG
ATCACTGGGTATCGAGGTGC

Product: putative two-component sensor histidine kinase transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MGATIARLSQSLRVQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPSALE
MFDTGFGDGVSYQVITAWGSLVSGFPDLPLPAVQRTGEDRAFHGADVRVLMLDHPVVGLPDDGAISVTVAVTHNSQYAMR
RQLWLSDFSKQFVLVFVASLVTILGLQRGLAPALRLRDALRQRGRNRLDPLPPEMVQSELQPLVHALNDYMERVQNQMAA
QRRFVSNAAHQLRTPLALISTQASVAAREADAARRDEALFALRTSTKQISRLASQLLTLSRAEPGSRRPRSDATDLTKAA
REILESHAEEALKRNIDVGLEAVRPVIVDGDATMLREMLVNLIDNAIRYTRPNGRVTVAVGQADGNAVVTVEDNGPGIPS
GEREQVFERFYRVIGIEGEGSGLGLAIVREVVEGAGGSVSLEDAEGGGLVVTVRLPLA

Sequences:

>Translated_458_residues
MGATIARLSQSLRVQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPSALE
MFDTGFGDGVSYQVITAWGSLVSGFPDLPLPAVQRTGEDRAFHGADVRVLMLDHPVVGLPDDGAISVTVAVTHNSQYAMR
RQLWLSDFSKQFVLVFVASLVTILGLQRGLAPALRLRDALRQRGRNRLDPLPPEMVQSELQPLVHALNDYMERVQNQMAA
QRRFVSNAAHQLRTPLALISTQASVAAREADAARRDEALFALRTSTKQISRLASQLLTLSRAEPGSRRPRSDATDLTKAA
REILESHAEEALKRNIDVGLEAVRPVIVDGDATMLREMLVNLIDNAIRYTRPNGRVTVAVGQADGNAVVTVEDNGPGIPS
GEREQVFERFYRVIGIEGEGSGLGLAIVREVVEGAGGSVSLEDAEGGGLVVTVRLPLA
>Mature_457_residues
GATIARLSQSLRVQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAEAVRVDEGGNVQVDVPPSALEM
FDTGFGDGVSYQVITAWGSLVSGFPDLPLPAVQRTGEDRAFHGADVRVLMLDHPVVGLPDDGAISVTVAVTHNSQYAMRR
QLWLSDFSKQFVLVFVASLVTILGLQRGLAPALRLRDALRQRGRNRLDPLPPEMVQSELQPLVHALNDYMERVQNQMAAQ
RRFVSNAAHQLRTPLALISTQASVAAREADAARRDEALFALRTSTKQISRLASQLLTLSRAEPGSRRPRSDATDLTKAAR
EILESHAEEALKRNIDVGLEAVRPVIVDGDATMLREMLVNLIDNAIRYTRPNGRVTVAVGQADGNAVVTVEDNGPGIPSG
EREQVFERFYRVIGIEGEGSGLGLAIVREVVEGAGGSVSLEDAEGGGLVVTVRLPLA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=323, Percent_Identity=33.1269349845201, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786783, Length=307, Percent_Identity=29.3159609120521, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=27.4725274725275, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=31.0810810810811, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=31.9587628865979, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=30, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788279, Length=300, Percent_Identity=26, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=28.5123966942149, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=24.1935483870968, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=301, Percent_Identity=28.9036544850498, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=29.1845493562232, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=27.0742358078603, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787894, Length=251, Percent_Identity=27.4900398406374, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=27.0386266094421, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787374, Length=294, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=28.2828282828283, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=28.8, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789149, Length=228, Percent_Identity=27.1929824561404, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=24.0802675585284, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=22.8813559322034, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49520; Mature: 49389

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGATIARLSQSLRVQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AVRVDEGGNVQVDVPPSALEMFDTGFGDGVSYQVITAWGSLVSGFPDLPLPAVQRTGEDR
HHHCCCCCCEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCC
AFHGADVRVLMLDHPVVGLPDDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFVLVFVASL
CCCCCCEEEEEECCCEECCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
VTILGLQRGLAPALRLRDALRQRGRNRLDPLPPEMVQSELQPLVHALNDYMERVQNQMAA
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRFVSNAAHQLRTPLALISTQASVAAREADAARRDEALFALRTSTKQISRLASQLLTLS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEPGSRRPRSDATDLTKAAREILESHAEEALKRNIDVGLEAVRPVIVDGDATMLREMLV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCHHHHHHHHH
NLIDNAIRYTRPNGRVTVAVGQADGNAVVTVEDNGPGIPSGEREQVFERFYRVIGIEGEG
HHHHHHHHEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHEECCCCC
SGLGLAIVREVVEGAGGSVSLEDAEGGGLVVTVRLPLA
CCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure 
GATIARLSQSLRVQLLCWVLLTLLGAIGFNLYDSFWTADATAKLVTDRTLLASARVIAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
AVRVDEGGNVQVDVPPSALEMFDTGFGDGVSYQVITAWGSLVSGFPDLPLPAVQRTGEDR
HHHCCCCCCEEEECCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCC
AFHGADVRVLMLDHPVVGLPDDGAISVTVAVTHNSQYAMRRQLWLSDFSKQFVLVFVASL
CCCCCCEEEEEECCCEECCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
VTILGLQRGLAPALRLRDALRQRGRNRLDPLPPEMVQSELQPLVHALNDYMERVQNQMAA
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRFVSNAAHQLRTPLALISTQASVAAREADAARRDEALFALRTSTKQISRLASQLLTLS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEPGSRRPRSDATDLTKAAREILESHAEEALKRNIDVGLEAVRPVIVDGDATMLREMLV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCHHHHHHHHH
NLIDNAIRYTRPNGRVTVAVGQADGNAVVTVEDNGPGIPSGEREQVFERFYRVIGIEGEG
HHHHHHHHEECCCCEEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHEECCCCC
SGLGLAIVREVVEGAGGSVSLEDAEGGGLVVTVRLPLA
CCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]