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The map label for this gene is tctD [H]

Identifier: 116249330

GI number: 116249330

Start: 718666

End: 719334

Strand: Direct

Name: tctD [H]

Synonym: pRL120667

Alternate gene names: 116249330

Gene position: 718666-719334 (Clockwise)

Preceding gene: 116249329

Following gene: 116249331

Centisome position: 82.6

GC content: 59.04

Gene sequence:

>669_bases
ATGCGACTGCTTGTGGTGGAGGACAACAAGGATCTGGCGGCCTGGCTGGGTAAAGCCCTGCGACAGGCGCAATACGCTAT
CGACATTGCCCATGACGGCGAGGACGCGGAGCATATGCTCAAGGTGGCGGAGTATTCGGCGATGATCCTCGACCTGGCGC
TGCCCAAGCTCGACGGATTGACGCTGTTGAAGCGATTGCGGCAGTCCGGAAACAAGCTGCCGGTCATCATCTTGACCGCC
AATGCGAGCCTGGACGGCCGTGTTGCAGGGCTTGACAGCGGTGCCGACGACTATCTCGCCAAACCCTTCGAAATCGCCGA
GCTCGAAGCGAGGATTCGTGCAGTGGTCCGCCGCGGACAGGACCGGGCATCATCCGAAATCACCGTCGGCAACCTGCGTT
TCTCCGGCGGGACGCGGCAGTTTTTTGTCGCCGACGAGTTGCTGCAACTGACGCCGCGCGAATATGCCGTGCTTGAGCAG
CTCGTCATGAAGCTTGGCAACACAGTCTCGAAAGCCGCCCTTTCTGAAAGTGTGTTCGGTTTCGACGACGAGGCGGATCC
GAGCGCCATCGAAATCTACGTCCACCGGCTGCGAAAGAAACTCGAGAGCAGTTCGGTTCAAATTGCCACGTTGCGCGGAC
TTGGTTATCTCCTCAGACATGTCCAATAG

Upstream 100 bases:

>100_bases
CTTAGGGTGATCGCATCTCCTTCTGAACAGAGGCCAAGCATCAGCTGTGGAAACCGTGTCGCGCTTCCGCCGGACCGCCT
GCCCATGCTAAGGAGGTCGG

Downstream 100 bases:

>100_bases
CCTCGTCACCAAGGTGGGCGCGACGATCGCGCGGCTCAGCCAGAGCCTGAGGGTGCAGCTGCTCTGCTGGGTGCTGCTGA
CCCTGTTAGGGGCGATCGGC

Product: putative two-component response regulator transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGLTLLKRLRQSGNKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGNLRFSGGTRQFFVADELLQLTPREYAVLEQ
LVMKLGNTVSKAALSESVFGFDDEADPSAIEIYVHRLRKKLESSSVQIATLRGLGYLLRHVQ

Sequences:

>Translated_222_residues
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGLTLLKRLRQSGNKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGNLRFSGGTRQFFVADELLQLTPREYAVLEQ
LVMKLGNTVSKAALSESVFGFDDEADPSAIEIYVHRLRKKLESSSVQIATLRGLGYLLRHVQ
>Mature_222_residues
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGLTLLKRLRQSGNKLPVIILTA
NASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQDRASSEITVGNLRFSGGTRQFFVADELLQLTPREYAVLEQ
LVMKLGNTVSKAALSESVFGFDDEADPSAIEIYVHRLRKKLESSSVQIATLRGLGYLLRHVQ

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=43.5779816513761, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=38.9908256880734, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=34.8623853211009, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=34.3891402714932, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=36.8181818181818, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.6828193832599, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.8421052631579, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=31.3636363636364, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=30.6666666666667, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.5315315315315, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI1786911, Length=177, Percent_Identity=35.5932203389831, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=26.9911504424779, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=29.0178571428571, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=31.6176470588235, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=32.2314049586777, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=37.2549019607843, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=88, Percent_Identity=35.2272727272727, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24502; Mature: 24502

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGL
CEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
TLLKRLRQSGNKLPVIILTANASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQ
HHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
DRASSEITVGNLRFSGGTRQFFVADELLQLTPREYAVLEQLVMKLGNTVSKAALSESVFG
CCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FDDEADPSAIEIYVHRLRKKLESSSVQIATLRGLGYLLRHVQ
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MRLLVVEDNKDLAAWLGKALRQAQYAIDIAHDGEDAEHMLKVAEYSAMILDLALPKLDGL
CEEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
TLLKRLRQSGNKLPVIILTANASLDGRVAGLDSGADDYLAKPFEIAELEARIRAVVRRGQ
HHHHHHHHCCCCCEEEEEEECCCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHCC
DRASSEITVGNLRFSGGTRQFFVADELLQLTPREYAVLEQLVMKLGNTVSKAALSESVFG
CCCCCCEEEEEEEECCCCEEEEHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCC
FDDEADPSAIEIYVHRLRKKLESSSVQIATLRGLGYLLRHVQ
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]