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The map label for this gene is ltrA [H]

Identifier: 116249208

GI number: 116249208

Start: 592186

End: 593082

Strand: Direct

Name: ltrA [H]

Synonym: pRL120544

Alternate gene names: 116249208

Gene position: 592186-593082 (Clockwise)

Preceding gene: 116249206

Following gene: 116249212

Centisome position: 68.07

GC content: 60.31

Gene sequence:

>897_bases
ATGTTTGACGGACGATTATTGAATGGCGTGAGCGTACTGGCCGCCGTTATCGAGAGCGGAAGTTTCGCGCGGGCGGCGGA
GCTAATGGGACTATCGGCCTCGGGTGTCAGCCGCGCCATTTCCCGACTGGAGGGGCGGATCGGTCTGCGGCTGCTCGACC
GGACAACACGCACGATGCGGCTCACCGATGACGGCGCGCGGTTCTACCAACAGGTGGCCCCACTCTTGAGCGGCATCGAA
GAGGCTGCGCAGACAGCTGTTGGCGCCAGACAGGCGGTGCGTGGCCGACTGCGAGTCAATGTCGACCCATATTTCTCACG
CCTTGTGCTCGGCCCGCGGCTCGGCGCCTTCCTCGACCGTTACCCGGATATCCAGATCGAGGTCATCACCCGCAACGAGA
TCGGCGATCTTGTTGCTGATGGCATGGACGTCGCTGTGCGCTTTGGCGAGCCTGCACAACGGTCGCTTATTTCGCGCCTG
TTGATGCAGACGCGCGTGATCACGATTGCGGCTCCCGTTTATATCGAGCGACATGGTCGGCCGGGCCGTCCACAGGATTT
GAGTGAGCATACCTGTATCCAGTTCCAGGACCCGCTGACTGCAAGGCCTTTCGAATGGGAGCTTCGGCGGCGTGAAGAGG
TCGTCTCGATCGAGACCCGCAGCCGCATTTTAGTCAACGATGCCGGCACGACCTTGGCGACCTGCCTTGCGGGGATAGGC
ATCGCGCAAGTCTTCTCACTCGGGATGGCGGATTATCTGAACAATGGGCAGCTCGTGAACCTCTTTCCCGACTGGTCGGA
CGAGACATTCCCGCTCTACGCCTTCTATCCCTCGCGTCAGCATGTTCCGGCTAAGGTCAGGGCCTTTATAGATTTCTGCG
TCGAGATCATCGAATAG

Upstream 100 bases:

>100_bases
AGCAGGTTGGCGGTTTGTTATGCTGATCATGTCCTTTGGCAGCATTTGACTGAAGCGCGCTTCTGTCACATGATTGGTGA
CTAAAAATCACGGATGCCCG

Downstream 100 bases:

>100_bases
ACGGAGGCGCCCCGTCGAGCGCCTCTGCTGGCTTAAGCCGGCCGCGGCTTTCTGGTTCTGGAAGTATCGTCTATGGGGTT
CTTTCATGCTTGGGCGGAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MFDGRLLNGVSVLAAVIESGSFARAAELMGLSASGVSRAISRLEGRIGLRLLDRTTRTMRLTDDGARFYQQVAPLLSGIE
EAAQTAVGARQAVRGRLRVNVDPYFSRLVLGPRLGAFLDRYPDIQIEVITRNEIGDLVADGMDVAVRFGEPAQRSLISRL
LMQTRVITIAAPVYIERHGRPGRPQDLSEHTCIQFQDPLTARPFEWELRRREEVVSIETRSRILVNDAGTTLATCLAGIG
IAQVFSLGMADYLNNGQLVNLFPDWSDETFPLYAFYPSRQHVPAKVRAFIDFCVEIIE

Sequences:

>Translated_298_residues
MFDGRLLNGVSVLAAVIESGSFARAAELMGLSASGVSRAISRLEGRIGLRLLDRTTRTMRLTDDGARFYQQVAPLLSGIE
EAAQTAVGARQAVRGRLRVNVDPYFSRLVLGPRLGAFLDRYPDIQIEVITRNEIGDLVADGMDVAVRFGEPAQRSLISRL
LMQTRVITIAAPVYIERHGRPGRPQDLSEHTCIQFQDPLTARPFEWELRRREEVVSIETRSRILVNDAGTTLATCLAGIG
IAQVFSLGMADYLNNGQLVNLFPDWSDETFPLYAFYPSRQHVPAKVRAFIDFCVEIIE
>Mature_298_residues
MFDGRLLNGVSVLAAVIESGSFARAAELMGLSASGVSRAISRLEGRIGLRLLDRTTRTMRLTDDGARFYQQVAPLLSGIE
EAAQTAVGARQAVRGRLRVNVDPYFSRLVLGPRLGAFLDRYPDIQIEVITRNEIGDLVADGMDVAVRFGEPAQRSLISRL
LMQTRVITIAAPVYIERHGRPGRPQDLSEHTCIQFQDPLTARPFEWELRRREEVVSIETRSRILVNDAGTTLATCLAGIG
IAQVFSLGMADYLNNGQLVNLFPDWSDETFPLYAFYPSRQHVPAKVRAFIDFCVEIIE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=31.3588850174216, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=33.1034482758621, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI145693193, Length=292, Percent_Identity=29.1095890410959, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=31.4189189189189, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=30.9027777777778, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=25.4355400696864, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=24.9097472924188, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=27.0627062706271, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789173, Length=261, Percent_Identity=27.9693486590038, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790011, Length=295, Percent_Identity=23.728813559322, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=33.5664335664336, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786448, Length=285, Percent_Identity=24.5614035087719, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789204, Length=123, Percent_Identity=31.7073170731707, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=305, Percent_Identity=24.9180327868852, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33123; Mature: 33123

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDGRLLNGVSVLAAVIESGSFARAAELMGLSASGVSRAISRLEGRIGLRLLDRTTRTMR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCEEE
LTDDGARFYQQVAPLLSGIEEAAQTAVGARQAVRGRLRVNVDPYFSRLVLGPRLGAFLDR
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCHHHHHHHC
YPDIQIEVITRNEIGDLVADGMDVAVRFGEPAQRSLISRLLMQTRVITIAAPVYIERHGR
CCCCEEEEEECCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEECEEEEECCC
PGRPQDLSEHTCIQFQDPLTARPFEWELRRREEVVSIETRSRILVNDAGTTLATCLAGIG
CCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCCEEEEECCCHHHHHHHHHHH
IAQVFSLGMADYLNNGQLVNLFPDWSDETFPLYAFYPSRQHVPAKVRAFIDFCVEIIE
HHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFDGRLLNGVSVLAAVIESGSFARAAELMGLSASGVSRAISRLEGRIGLRLLDRTTRTMR
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCEEE
LTDDGARFYQQVAPLLSGIEEAAQTAVGARQAVRGRLRVNVDPYFSRLVLGPRLGAFLDR
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHCCHHHHHHHC
YPDIQIEVITRNEIGDLVADGMDVAVRFGEPAQRSLISRLLMQTRVITIAAPVYIERHGR
CCCCEEEEEECCHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHEEEECEEEEECCC
PGRPQDLSEHTCIQFQDPLTARPFEWELRRREEVVSIETRSRILVNDAGTTLATCLAGIG
CCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCCEEEEECCCHHHHHHHHHHH
IAQVFSLGMADYLNNGQLVNLFPDWSDETFPLYAFYPSRQHVPAKVRAFIDFCVEIIE
HHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]