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The map label for this gene is dhaK2 [H]

Identifier: 116249052

GI number: 116249052

Start: 417655

End: 418299

Strand: Reverse

Name: dhaK2 [H]

Synonym: pRL120386

Alternate gene names: 116249052

Gene position: 418299-417655 (Counterclockwise)

Preceding gene: 116249053

Following gene: 116249051

Centisome position: 48.08

GC content: 64.65

Gene sequence:

>645_bases
ATGATGTTTACGACCGAAGACCTGCAGCGCATGTTTGCCGGGATTGCCGAGGATATTGCAGCAGAGAGCGACCATCTCTG
CGCGTTGGACGGCGCCATCGGCGATGGAGATCACGGCCTTGCCATGGATGCGGGCTGCCAGGCCGCGGCGAAAGCGGTCG
GCGAACTTGACCCCGGGATTGCCCCGACAACCGCATTCAACGTCGCGGCAAAGGCATTCCTGAATGCGGTCGGCGCTTCG
TCCGGCCCGTTATATGCCACGGCCTTCATGCGCGCCGGAGCAGCCGCCAAAGACAAGCAGACTTTGAGCGACGACGACTT
CCTGCGCGTCTTCGCGGCAATGGCGCGGGGAATCCAGGAACGCGGAAAGGCCGAACCCGGTGAAAAGACAATGGTTGACG
CCTGGAGGCCCGCGGCTGACGCGGCACTCGATGCCCGTCAGTCGGGAGAGCCCCTCCCCCAATGCTTCGAGGCGGCCGAG
CGGGCAGCGCGCGCAGGCTGTGAAGCGACCGGCAACATGACGGCGGCCAAGGGACGGGCTTCGCGATTGGGGGACCGCGT
GATCGGGCACATCGATCCCGGCGCCGCCTCCGCAGTCATCATCATCGCCGCGATGGCCAAATTTGCTCAGCATCACGATG
GTTAG

Upstream 100 bases:

>100_bases
CGAAATGGCCGGCGCGTCGATCACGGTCATGCATCTCGACGACGAGCTTCAGCGATTGATCGACCACCCCTGTGATTGCG
CGATGTTTGCGAGGTAATCG

Downstream 100 bases:

>100_bases
CTCATCATACCAGTTGACATGTCAATGACTATCTGCAACAAGGGGCCCGGCTTTACAAGAGGAGGACGGTAATGCTGACC
CTTTCTGCGAAATTGAAGAC

Product: putative dihydroxyacetone kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MMFTTEDLQRMFAGIAEDIAAESDHLCALDGAIGDGDHGLAMDAGCQAAAKAVGELDPGIAPTTAFNVAAKAFLNAVGAS
SGPLYATAFMRAGAAAKDKQTLSDDDFLRVFAAMARGIQERGKAEPGEKTMVDAWRPAADAALDARQSGEPLPQCFEAAE
RAARAGCEATGNMTAAKGRASRLGDRVIGHIDPGAASAVIIIAAMAKFAQHHDG

Sequences:

>Translated_214_residues
MMFTTEDLQRMFAGIAEDIAAESDHLCALDGAIGDGDHGLAMDAGCQAAAKAVGELDPGIAPTTAFNVAAKAFLNAVGAS
SGPLYATAFMRAGAAAKDKQTLSDDDFLRVFAAMARGIQERGKAEPGEKTMVDAWRPAADAALDARQSGEPLPQCFEAAE
RAARAGCEATGNMTAAKGRASRLGDRVIGHIDPGAASAVIIIAAMAKFAQHHDG
>Mature_214_residues
MMFTTEDLQRMFAGIAEDIAAESDHLCALDGAIGDGDHGLAMDAGCQAAAKAVGELDPGIAPTTAFNVAAKAFLNAVGAS
SGPLYATAFMRAGAAAKDKQTLSDDDFLRVFAAMARGIQERGKAEPGEKTMVDAWRPAADAALDARQSGEPLPQCFEAAE
RAARAGCEATGNMTAAKGRASRLGDRVIGHIDPGAASAVIIIAAMAKFAQHHDG

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=176, Percent_Identity=36.3636363636364, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1787449, Length=191, Percent_Identity=39.2670157068063, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: NA

Molecular weight: Translated: 21962; Mature: 21962

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFTTEDLQRMFAGIAEDIAAESDHLCALDGAIGDGDHGLAMDAGCQAAAKAVGELDPGI
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
APTTAFNVAAKAFLNAVGASSGPLYATAFMRAGAAAKDKQTLSDDDFLRVFAAMARGIQE
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGKAEPGEKTMVDAWRPAADAALDARQSGEPLPQCFEAAERAARAGCEATGNMTAAKGRA
HCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
SRLGDRVIGHIDPGAASAVIIIAAMAKFAQHHDG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMFTTEDLQRMFAGIAEDIAAESDHLCALDGAIGDGDHGLAMDAGCQAAAKAVGELDPGI
CCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
APTTAFNVAAKAFLNAVGASSGPLYATAFMRAGAAAKDKQTLSDDDFLRVFAAMARGIQE
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RGKAEPGEKTMVDAWRPAADAALDARQSGEPLPQCFEAAERAARAGCEATGNMTAAKGRA
HCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
SRLGDRVIGHIDPGAASAVIIIAAMAKFAQHHDG
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]