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The map label for this gene is erfK [H]

Identifier: 116249009

GI number: 116249009

Start: 365889

End: 366569

Strand: Direct

Name: erfK [H]

Synonym: pRL120340

Alternate gene names: 116249009

Gene position: 365889-366569 (Clockwise)

Preceding gene: 116249008

Following gene: 116249010

Centisome position: 42.06

GC content: 59.47

Gene sequence:

>681_bases
TTGCCGATGGTGGGGACACGCAGGGATATTTTGCTTGGTAGTTTGGCGTTACTTGGCGCCGCCGCGGTTCAGAAACCGGC
ATTTGCCGTGGCGTCTTCCAATTTTACCGGCACCGCGGTCGACAATGGCGTGACGTTCCAAAGGACGAACTTCGCCAAGA
TTGATAAGAAGTGGCAACGCCGGGTCGTCAAATATTTCAGCAGCGAGCCGATCGGCACAGTGGTCGTCGATACAAGGCAT
CATTTTCTCTACGTGATTATGGAGAACAAGACGGCCATCCGCTACGGCGTCGGCGTCGGCCGCGAGGGCTTCAAATGGTT
CGGCCGCGCCACGATCGACGCTAAATCGCTTTGGCCGCGCTGGACACCGCCACCGGAGATGCGCAAGCGCCATCCGGAAC
TGCCCGAATTCGTGGCGGGAGGTTCGCCAAAGAATCCGCTCGGTCCCCGCGCCATGTACCTGCATCGTGACGGCGTCGAC
ACCGGCTATCGCTTCCACGGCACGGTGGAGCCTTGGAGCATCGGTAAGGATGCCTCCAGCGGCTGTATCCGCATGTTCAA
CGAAGACGCCATCGATCTTTACCAGCGTTGCCCGATCGGCACCGCTGTGCAGGTTCTGCCGCATATTGCCGACCAGGCTG
AAAGTGCCGCGCAGGTCAGCCAAACAACTCCGGTCGAATGA

Upstream 100 bases:

>100_bases
CGGCAACCCGATCTCGGTCTTTAAGGGCAGAAGAATTTTCTGTTGTCGCAAATGAAAATTCTGATTTATTGTTACTTCGC
TGCTGGCTTTAAGGGGGATA

Downstream 100 bases:

>100_bases
GGAATATCACCCTGATGTTTGCTCCGACCGGATATACGAGGCGCCTTGCTGTCGCGGCCATGCTCCTGGCGCTCACTGCC
TGCACCACCACCAAGGTCGC

Product: ErfK/YbiS/YhnG family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MPMVGTRRDILLGSLALLGAAAVQKPAFAVASSNFTGTAVDNGVTFQRTNFAKIDKKWQRRVVKYFSSEPIGTVVVDTRH
HFLYVIMENKTAIRYGVGVGREGFKWFGRATIDAKSLWPRWTPPPEMRKRHPELPEFVAGGSPKNPLGPRAMYLHRDGVD
TGYRFHGTVEPWSIGKDASSGCIRMFNEDAIDLYQRCPIGTAVQVLPHIADQAESAAQVSQTTPVE

Sequences:

>Translated_226_residues
MPMVGTRRDILLGSLALLGAAAVQKPAFAVASSNFTGTAVDNGVTFQRTNFAKIDKKWQRRVVKYFSSEPIGTVVVDTRH
HFLYVIMENKTAIRYGVGVGREGFKWFGRATIDAKSLWPRWTPPPEMRKRHPELPEFVAGGSPKNPLGPRAMYLHRDGVD
TGYRFHGTVEPWSIGKDASSGCIRMFNEDAIDLYQRCPIGTAVQVLPHIADQAESAAQVSQTTPVE
>Mature_225_residues
PMVGTRRDILLGSLALLGAAAVQKPAFAVASSNFTGTAVDNGVTFQRTNFAKIDKKWQRRVVKYFSSEPIGTVVVDTRHH
FLYVIMENKTAIRYGVGVGREGFKWFGRATIDAKSLWPRWTPPPEMRKRHPELPEFVAGGSPKNPLGPRAMYLHRDGVDT
GYRFHGTVEPWSIGKDASSGCIRMFNEDAIDLYQRCPIGTAVQVLPHIADQAESAAQVSQTTPVE

Specific function: Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp, also known as the Braun lipoprotein) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YkuD family [H]

Homologues:

Organism=Escherichia coli, GI1788299, Length=143, Percent_Identity=34.965034965035, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787040, Length=143, Percent_Identity=31.4685314685315, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1787968, Length=140, Percent_Identity=35, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005490 [H]

Pfam domain/function: PF03734 YkuD [H]

EC number: NA

Molecular weight: Translated: 25030; Mature: 24899

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMVGTRRDILLGSLALLGAAAVQKPAFAVASSNFTGTAVDNGVTFQRTNFAKIDKKWQR
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEECCCEEEECCCHHHHHHHHHH
RVVKYFSSEPIGTVVVDTRHHFLYVIMENKTAIRYGVGVGREGFKWFGRATIDAKSLWPR
HHHHHHCCCCCEEEEEECCCEEEEEEEECCEEEEECCCCCCCHHHHHCCEEECHHHCCCC
WTPPPEMRKRHPELPEFVAGGSPKNPLGPRAMYLHRDGVDTGYRFHGTVEPWSIGKDASS
CCCCHHHHHCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCC
GCIRMFNEDAIDLYQRCPIGTAVQVLPHIADQAESAAQVSQTTPVE
CHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PMVGTRRDILLGSLALLGAAAVQKPAFAVASSNFTGTAVDNGVTFQRTNFAKIDKKWQR
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEECCCEEEECCCHHHHHHHHHH
RVVKYFSSEPIGTVVVDTRHHFLYVIMENKTAIRYGVGVGREGFKWFGRATIDAKSLWPR
HHHHHHCCCCCEEEEEECCCEEEEEEEECCEEEEECCCCCCCHHHHHCCEEECHHHCCCC
WTPPPEMRKRHPELPEFVAGGSPKNPLGPRAMYLHRDGVDTGYRFHGTVEPWSIGKDASS
CCCCHHHHHCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCC
GCIRMFNEDAIDLYQRCPIGTAVQVLPHIADQAESAAQVSQTTPVE
CHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592411; 9097040; 9278503; 9298646 [H]