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The map label for this gene is appC [H]

Identifier: 116249006

GI number: 116249006

Start: 362783

End: 363697

Strand: Direct

Name: appC [H]

Synonym: pRL120337

Alternate gene names: 116249006

Gene position: 362783-363697 (Clockwise)

Preceding gene: 116249005

Following gene: 116249007

Centisome position: 41.7

GC content: 61.2

Gene sequence:

>915_bases
ATGGCCGAACCACAAACGCAAGACACCAGCGCTCCAACGCCCGAACCCAGTCGTCTGTCGAAAGGGGTCACGGATTTCTT
CAGCTCTCCGGCAGCCGCGATCGCCTTCCTCACGCTGGTGATCATCTGTTGCCTGGCGCTGTTTGCGCCATGGATCTCTC
CGCAAAATCCCTATGATTTGATGCAGCTCGACATCATGGATGGACGGCTGCCGCCGGGGTCCGAATCCATGACCGGGCTT
GTCTATCACCTCGGTACCGACAGCCAGGGCCGCGATATCCTGTCCGGCATCCTCTATGGGTTGCGCACCTCCTTGCTGGT
GGGCGTTCTGTCGGCTTTCGCTGCTGCCATCATCGGAACCTCAGCCGGATTGTTTGCCGCTTACGTGGGAGGGCGCACGG
AAACCGCGATGATGCGGCTCGTCGATCTGCAGCTCTCGTTTCCCACCATATTGATGGCGCTCATGATGCTCGCCGTGCTC
GGCAAGGGCGTACCCAACGTCGTGATCGCACTGATCATCGCCGAGTGGGCGACCTATGCCCGAACGGTCCGCGGCACCGC
TCTGGTCGAGCGCGAGAAGGAATATATCGAGGCGGCCCGGATGCTGCGCCTGCCCGGATGGCGCATCCTCTTCAGGCACC
TGCTGCCGAACTGTCTTGCGCCGGTCATCGTCATCGCCACGATGCAGATCGCCCGGGCAATCGGCCTCGAAGCAACCTTG
TCCTTCCTCGGTCTCGGTGCATCCGTGACCGAACCCTCGCTCGGCATGCTGATCTCGACGGGCTACCAGTATCTACTGAC
GGGCCTTTACTGGATCAGCTTCTTTCCCGGCATTGCCCTTCTGGTCACGATCGCGGCGATCAATCTCGTCGGCGACCGGC
TGCGCGATGTCCTCAACCCGAGGAACATGTCATGA

Upstream 100 bases:

>100_bases
ATGATGATGGTGCTGCTCTTCGTCGTCCTCAATTTCATCATCGATATCTGTTATACCCTTCTGGATCCGCGGGTCCGGCT
GGAAGGAAAGGCTTGACCCC

Downstream 100 bases:

>100_bases
CCCCATTGCTGCAAGTGAGCAATCTCGTCACCGAATTCGGCGGCGGCAGGGGACGCCCCAGCCTTTGCGCCGTCAACGAT
GTGTCGTTCACGGTGGAGCG

Product: putative transmembrane component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAEPQTQDTSAPTPEPSRLSKGVTDFFSSPAAAIAFLTLVIICCLALFAPWISPQNPYDLMQLDIMDGRLPPGSESMTGL
VYHLGTDSQGRDILSGILYGLRTSLLVGVLSAFAAAIIGTSAGLFAAYVGGRTETAMMRLVDLQLSFPTILMALMMLAVL
GKGVPNVVIALIIAEWATYARTVRGTALVEREKEYIEAARMLRLPGWRILFRHLLPNCLAPVIVIATMQIARAIGLEATL
SFLGLGASVTEPSLGMLISTGYQYLLTGLYWISFFPGIALLVTIAAINLVGDRLRDVLNPRNMS

Sequences:

>Translated_304_residues
MAEPQTQDTSAPTPEPSRLSKGVTDFFSSPAAAIAFLTLVIICCLALFAPWISPQNPYDLMQLDIMDGRLPPGSESMTGL
VYHLGTDSQGRDILSGILYGLRTSLLVGVLSAFAAAIIGTSAGLFAAYVGGRTETAMMRLVDLQLSFPTILMALMMLAVL
GKGVPNVVIALIIAEWATYARTVRGTALVEREKEYIEAARMLRLPGWRILFRHLLPNCLAPVIVIATMQIARAIGLEATL
SFLGLGASVTEPSLGMLISTGYQYLLTGLYWISFFPGIALLVTIAAINLVGDRLRDVLNPRNMS
>Mature_303_residues
AEPQTQDTSAPTPEPSRLSKGVTDFFSSPAAAIAFLTLVIICCLALFAPWISPQNPYDLMQLDIMDGRLPPGSESMTGLV
YHLGTDSQGRDILSGILYGLRTSLLVGVLSAFAAAIIGTSAGLFAAYVGGRTETAMMRLVDLQLSFPTILMALMMLAVLG
KGVPNVVIALIIAEWATYARTVRGTALVEREKEYIEAARMLRLPGWRILFRHLLPNCLAPVIVIATMQIARAIGLEATLS
FLGLGASVTEPSLGMLISTGYQYLLTGLYWISFFPGIALLVTIAAINLVGDRLRDVLNPRNMS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=301, Percent_Identity=34.21926910299, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1787760, Length=299, Percent_Identity=32.4414715719064, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789964, Length=297, Percent_Identity=36.7003367003367, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1789889, Length=249, Percent_Identity=36.144578313253, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787498, Length=277, Percent_Identity=35.3790613718412, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787549, Length=280, Percent_Identity=27.5, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788505, Length=232, Percent_Identity=27.5862068965517, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32721; Mature: 32590

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPQTQDTSAPTPEPSRLSKGVTDFFSSPAAAIAFLTLVIICCLALFAPWISPQNPYDL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
MQLDIMDGRLPPGSESMTGLVYHLGTDSQGRDILSGILYGLRTSLLVGVLSAFAAAIIGT
HHEEHHCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SAGLFAAYVGGRTETAMMRLVDLQLSFPTILMALMMLAVLGKGVPNVVIALIIAEWATYA
HHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RTVRGTALVEREKEYIEAARMLRLPGWRILFRHLLPNCLAPVIVIATMQIARAIGLEATL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLGLGASVTEPSLGMLISTGYQYLLTGLYWISFFPGIALLVTIAAINLVGDRLRDVLNP
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RNMS
CCCC
>Mature Secondary Structure 
AEPQTQDTSAPTPEPSRLSKGVTDFFSSPAAAIAFLTLVIICCLALFAPWISPQNPYDL
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
MQLDIMDGRLPPGSESMTGLVYHLGTDSQGRDILSGILYGLRTSLLVGVLSAFAAAIIGT
HHEEHHCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SAGLFAAYVGGRTETAMMRLVDLQLSFPTILMALMMLAVLGKGVPNVVIALIIAEWATYA
HHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
RTVRGTALVEREKEYIEAARMLRLPGWRILFRHLLPNCLAPVIVIATMQIARAIGLEATL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLGLGASVTEPSLGMLISTGYQYLLTGLYWISFFPGIALLVTIAAINLVGDRLRDVLNP
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RNMS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]