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The map label for this gene is appB [H]

Identifier: 116249005

GI number: 116249005

Start: 361804

End: 362778

Strand: Direct

Name: appB [H]

Synonym: pRL120336

Alternate gene names: 116249005

Gene position: 361804-362778 (Clockwise)

Preceding gene: 116249004

Following gene: 116249006

Centisome position: 41.59

GC content: 57.44

Gene sequence:

>975_bases
ATGGTCACATCCATCATCAGGCGATTGATACAGGCGCTGTTCGTCATTGTCGCGATGACGATCATCGTCTTCATCGGTGT
CAATGTGATCGGCAATCCGGTCGACATCCTGATCAACCCGGACGCCAACCAGGCGGAGCGGGCACTCGTTATCGCGCATT
ACGGCCTGGATCAGCCGCTGTGGAAACAGTATCTGCTGTTTCTCCAAGGGCTTCTGCACGGGGACTTCGGCAACAGCTTC
GTTTATGGGCGGCCGGCGCTGGGCCTGATCCTCGAACGTCTCCCGGCGACGCTCGAACTGGCGATCACGGCTCTTGTCAT
TGCACTGCTGTTCGGCTTGCCGCTTGGGCTGTATGCAGGGCTCTACCCCAATCGCATTTCCTCCAAGCTGATCATGAGCG
GCTCAATTCTGGGTTTCTCGCTTCCGACCTTCTGGGTCGGTCTCATGCTGATCATGGTGTTTTCCGTCGAGCTCGGCTGG
TTGCCGACGAATGGCCGCGGCCCAACGCGGGAACTGCTTGGCGCACAATGGTCGTTTCTGACCGGGGACGGCATCAGGCA
TCTTCTATTGCCGGCCTTCAACCTGGCTCTGTTCAAGACGTCGCTCATTCTTCGGCTGACCCGCGCCGGTGTACAGGAGG
TCCTTCCCCAGGACTATGTGAAGTTTGCCCGCGCCAAGGGATTGCGAGAGCGGCGGATCATTTCGGTGCACGTTCTCAAG
AACCTGATGATCCCGGTGGTGACCATCATCGGTCTCGAGTTCGGCTCACTCATCGCCTTTTCGGTCGTCACCGAAAGCAT
CTTTGCGTGGCCGGGCATGGGCAAGCTCATCATTGACTCGATCAATCTTCTCGATCGCCCGGTCATCGTCGCCTACCTGA
TGATGATGGTGCTGCTCTTCGTCGTCCTCAATTTCATCATCGATATCTGTTATACCCTTCTGGATCCGCGGGTCCGGCTG
GAAGGAAAGGCTTGA

Upstream 100 bases:

>100_bases
TGCGGCAACGACATGCGTAAAAACAAAGACGTCGATTCAAAGTGTTACAGCGTCTTTTGCGGCTCTCGGAAAGACGCTCG
GCGCTGTAGGGAGAGGTTCA

Downstream 100 bases:

>100_bases
CCCCATGGCCGAACCACAAACGCAAGACACCAGCGCTCCAACGCCCGAACCCAGTCGTCTGTCGAAAGGGGTCACGGATT
TCTTCAGCTCTCCGGCAGCC

Product: putative transmembrane ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVTSIIRRLIQALFVIVAMTIIVFIGVNVIGNPVDILINPDANQAERALVIAHYGLDQPLWKQYLLFLQGLLHGDFGNSF
VYGRPALGLILERLPATLELAITALVIALLFGLPLGLYAGLYPNRISSKLIMSGSILGFSLPTFWVGLMLIMVFSVELGW
LPTNGRGPTRELLGAQWSFLTGDGIRHLLLPAFNLALFKTSLILRLTRAGVQEVLPQDYVKFARAKGLRERRIISVHVLK
NLMIPVVTIIGLEFGSLIAFSVVTESIFAWPGMGKLIIDSINLLDRPVIVAYLMMMVLLFVVLNFIIDICYTLLDPRVRL
EGKA

Sequences:

>Translated_324_residues
MVTSIIRRLIQALFVIVAMTIIVFIGVNVIGNPVDILINPDANQAERALVIAHYGLDQPLWKQYLLFLQGLLHGDFGNSF
VYGRPALGLILERLPATLELAITALVIALLFGLPLGLYAGLYPNRISSKLIMSGSILGFSLPTFWVGLMLIMVFSVELGW
LPTNGRGPTRELLGAQWSFLTGDGIRHLLLPAFNLALFKTSLILRLTRAGVQEVLPQDYVKFARAKGLRERRIISVHVLK
NLMIPVVTIIGLEFGSLIAFSVVTESIFAWPGMGKLIIDSINLLDRPVIVAYLMMMVLLFVVLNFIIDICYTLLDPRVRL
EGKA
>Mature_324_residues
MVTSIIRRLIQALFVIVAMTIIVFIGVNVIGNPVDILINPDANQAERALVIAHYGLDQPLWKQYLLFLQGLLHGDFGNSF
VYGRPALGLILERLPATLELAITALVIALLFGLPLGLYAGLYPNRISSKLIMSGSILGFSLPTFWVGLMLIMVFSVELGW
LPTNGRGPTRELLGAQWSFLTGDGIRHLLLPAFNLALFKTSLILRLTRAGVQEVLPQDYVKFARAKGLRERRIISVHVLK
NLMIPVVTIIGLEFGSLIAFSVVTESIFAWPGMGKLIIDSINLLDRPVIVAYLMMMVLLFVVLNFIIDICYTLLDPRVRL
EGKA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=322, Percent_Identity=37.2670807453416, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=35.9050445103858, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789888, Length=332, Percent_Identity=35.8433734939759, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1787550, Length=280, Percent_Identity=34.6428571428571, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=36.6666666666667, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1787497, Length=330, Percent_Identity=30.9090909090909, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788504, Length=286, Percent_Identity=28.3216783216783, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35892; Mature: 35892

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTSIIRRLIQALFVIVAMTIIVFIGVNVIGNPVDILINPDANQAERALVIAHYGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHEEEEEECCCCCHH
WKQYLLFLQGLLHGDFGNSFVYGRPALGLILERLPATLELAITALVIALLFGLPLGLYAG
HHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
LYPNRISSKLIMSGSILGFSLPTFWVGLMLIMVFSVELGWLPTNGRGPTRELLGAQWSFL
CCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCEE
TGDGIRHLLLPAFNLALFKTSLILRLTRAGVQEVLPQDYVKFARAKGLRERRIISVHVLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NLMIPVVTIIGLEFGSLIAFSVVTESIFAWPGMGKLIIDSINLLDRPVIVAYLMMMVLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
VVLNFIIDICYTLLDPRVRLEGKA
HHHHHHHHHHHHHCCCCEECCCCC
>Mature Secondary Structure
MVTSIIRRLIQALFVIVAMTIIVFIGVNVIGNPVDILINPDANQAERALVIAHYGLDQPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHEEEEEECCCCCHH
WKQYLLFLQGLLHGDFGNSFVYGRPALGLILERLPATLELAITALVIALLFGLPLGLYAG
HHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
LYPNRISSKLIMSGSILGFSLPTFWVGLMLIMVFSVELGWLPTNGRGPTRELLGAQWSFL
CCCHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCEE
TGDGIRHLLLPAFNLALFKTSLILRLTRAGVQEVLPQDYVKFARAKGLRERRIISVHVLK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NLMIPVVTIIGLEFGSLIAFSVVTESIFAWPGMGKLIIDSINLLDRPVIVAYLMMMVLLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
VVLNFIIDICYTLLDPRVRLEGKA
HHHHHHHHHHHHHCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]