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The map label for this gene is agaR [H]

Identifier: 116248925

GI number: 116248925

Start: 266551

End: 267345

Strand: Reverse

Name: agaR [H]

Synonym: pRL120255

Alternate gene names: 116248925

Gene position: 267345-266551 (Counterclockwise)

Preceding gene: 116248926

Following gene: 116248924

Centisome position: 30.73

GC content: 58.99

Gene sequence:

>795_bases
TTGAGCCAGGCAGTTGGAGTGAAGGTCGATCGACTGGATGCCATTCGCAGCCACCTCTACGCGAACGGCTTTTCGACCAT
TCAGGCGCTTGCCGATGCGATCGGAGCATCGCTTGCCACGGTTCGTAGAGACCTGCAGATCCTTGAGCAGGAGGGCGCTA
TTGATCGCGTGCATGGTGGAGCGCGCATTGCCGAAGGATCATCGGTGGAAGTGGCATTTCAGGAGCGCGAAAAGCGCCAT
CTATCGGCCAAACGGGCGATTGCCACCGCGGCCTACGACCTGCTTCATCCACGTACGGCAATCTTTCTCGACGCGGGAAC
CACCGTCCTGCAGCTTGCGCGCCTCGTTCGCATCAACCCCATGCCGCTCAGGATATTCACCAACGGCCTGACGGTAGCGC
AGGAATTCCTGAATATTCCGAATTTGGAAGTGGTGCTTCTCGGCGGTCAGCTGCGCAGCGAGAATGCGTCGCTTGTCGGA
CCTCAGGCGGAGGCAATGCTGGAAACATTATGGTTCGACCAGCTCTTTCTTGGCGCCAGCGCCATTAGCTCCGACGGTGC
GATTTATAGCGTGGACAGTGCGGAAGCGAGCCTCAACCGGCGCATGCTGGCTCGGTCGGCCAATCGTTTCGTCCTGGCCG
ATTCCTCGAAATTCGGAACCACAGCGACCTACAAGGTCGCGCCGCTGGACACCGCGAAAGTCATTACCGATTCCGGGCTT
TCGCGGCATTGGCGTGACGAGCTTGTCAACTTCGGCGTCGACGCAACAATCGCGGATCTGAGGGCGAAAGAGTGA

Upstream 100 bases:

>100_bases
GTCATCCAATAAATCAAAAAACGTCAGAAAATTGATTGACACTGATCATTTGAAATGAAATCATGATCGAAATTGGGATC
GGCCGTGAGGGAGGTTTTCG

Downstream 100 bases:

>100_bases
GCGACGCGCTGATCCTCGGCATCGACGGTGGCGGAAGCAAGGTGCTGGTTGCGCTTGCGGACAAGCGTGGCCGGATATTG
CGGCGGTCCCGCGGCCATGG

Product: deoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSQAVGVKVDRLDAIRSHLYANGFSTIQALADAIGASLATVRRDLQILEQEGAIDRVHGGARIAEGSSVEVAFQEREKRH
LSAKRAIATAAYDLLHPRTAIFLDAGTTVLQLARLVRINPMPLRIFTNGLTVAQEFLNIPNLEVVLLGGQLRSENASLVG
PQAEAMLETLWFDQLFLGASAISSDGAIYSVDSAEASLNRRMLARSANRFVLADSSKFGTTATYKVAPLDTAKVITDSGL
SRHWRDELVNFGVDATIADLRAKE

Sequences:

>Translated_264_residues
MSQAVGVKVDRLDAIRSHLYANGFSTIQALADAIGASLATVRRDLQILEQEGAIDRVHGGARIAEGSSVEVAFQEREKRH
LSAKRAIATAAYDLLHPRTAIFLDAGTTVLQLARLVRINPMPLRIFTNGLTVAQEFLNIPNLEVVLLGGQLRSENASLVG
PQAEAMLETLWFDQLFLGASAISSDGAIYSVDSAEASLNRRMLARSANRFVLADSSKFGTTATYKVAPLDTAKVITDSGL
SRHWRDELVNFGVDATIADLRAKE
>Mature_263_residues
SQAVGVKVDRLDAIRSHLYANGFSTIQALADAIGASLATVRRDLQILEQEGAIDRVHGGARIAEGSSVEVAFQEREKRHL
SAKRAIATAAYDLLHPRTAIFLDAGTTVLQLARLVRINPMPLRIFTNGLTVAQEFLNIPNLEVVLLGGQLRSENASLVGP
QAEAMLETLWFDQLFLGASAISSDGAIYSVDSAEASLNRRMLARSANRFVLADSSKFGTTATYKVAPLDTAKVITDSGLS
RHWRDELVNFGVDATIADLRAKE

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=33.596837944664, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87082344, Length=204, Percent_Identity=38.2352941176471, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI226510968, Length=235, Percent_Identity=34.0425531914894, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=30.8, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789829, Length=244, Percent_Identity=27.8688524590164, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=231, Percent_Identity=29.004329004329, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790753, Length=243, Percent_Identity=28.3950617283951, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790635, Length=203, Percent_Identity=27.0935960591133, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788069, Length=237, Percent_Identity=25.7383966244726, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28574; Mature: 28443

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQAVGVKVDRLDAIRSHLYANGFSTIQALADAIGASLATVRRDLQILEQEGAIDRVHGG
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
ARIAEGSSVEVAFQEREKRHLSAKRAIATAAYDLLHPRTAIFLDAGTTVLQLARLVRINP
CEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCC
MPLRIFTNGLTVAQEFLNIPNLEVVLLGGQLRSENASLVGPQAEAMLETLWFDQLFLGAS
CEEEEEECHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
AISSDGAIYSVDSAEASLNRRMLARSANRFVLADSSKFGTTATYKVAPLDTAKVITDSGL
HHCCCCCEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHCCCC
SRHWRDELVNFGVDATIADLRAKE
HHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure 
SQAVGVKVDRLDAIRSHLYANGFSTIQALADAIGASLATVRRDLQILEQEGAIDRVHGG
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
ARIAEGSSVEVAFQEREKRHLSAKRAIATAAYDLLHPRTAIFLDAGTTVLQLARLVRINP
CEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCC
MPLRIFTNGLTVAQEFLNIPNLEVVLLGGQLRSENASLVGPQAEAMLETLWFDQLFLGAS
CEEEEEECHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
AISSDGAIYSVDSAEASLNRRMLARSANRFVLADSSKFGTTATYKVAPLDTAKVITDSGL
HHCCCCCEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCCHHHHHHCCCC
SRHWRDELVNFGVDATIADLRAKE
HHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]