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The map label for this gene is appB [H]

Identifier: 116248913

GI number: 116248913

Start: 254597

End: 255511

Strand: Reverse

Name: appB [H]

Synonym: pRL120243

Alternate gene names: 116248913

Gene position: 255511-254597 (Counterclockwise)

Preceding gene: 116248914

Following gene: 116248912

Centisome position: 29.37

GC content: 59.67

Gene sequence:

>915_bases
ATGAAGAGTTTCATCGGCAAACGCGCGATCGCCAGTGGCGTATCGCTCGTGGTGCTTATCGTCATCGTGTTCTTCCTGTC
CCGACTGACGGGCGATCCGACCGACCTTTATCTGCCGATCGATGCGACCACGGAAATGCGCCAGCAATTCCGCGAGATGA
ACGGTTTCAACGATCCGTTGATCATCCAGTTCGGCCGTTATGTCTCGGATCTTGCCCAAGGCAATTTCGGTCAGTCACTG
CGACAGGCCCGTCCGGCCATGGATGTCGTGCTGGAGGCTTTCGTGTGGACCTTCTGGCTGGCTGTCATCACCATGGCGCT
GGTCACGGTCGCCGCGATCGTCATCGGTTCGCTCGCGGCGTTTCGCGTCGGCGGCGTCTTCGACCGTCTCGCCACTTTCT
TCTCACTGATCGGCGCTGCGGCGCCGGATTTCTGGCTGGCCATCGTGGCGATCGTCATTTTCGCCGTCAAACTGCATGTC
CTGCCGACATCGGGAACGGGAACTTTCTGGCACTGGGTCCTGCCGGTCAGCGTGCTGTTCATCCGGCCTTTCGGCCTGAT
CCTGCAGGTGGTCCGCGGCTCGATGATCAGTGTTCTGTCTTCCGCCTACGTGAAGACGGCCCGCGCCAAGGGTGTCCGCT
CGAACTCGATCATCTTCATTCACGGACTGCGCAACGCCATGCTGCCGGTGATCACAGTCATCGGCGACCAGGCGGCCGCC
ATCCTGAACGGTGCCGTCGTCGTCGAGACGGTGTTTGGCTTTCCTGGTATCGGCAAGCTGATGATCGATTCCATTCTGCT
TCGCGATTTCGCCGTCGTGCTGGCCGTCATCATGGTCTCGGCACTGGCGATCTTCATCATGAACCTGTTGATCGACATCG
CCTATGCGCTGCTCGATCCGCGCATCCGGTATTGA

Upstream 100 bases:

>100_bases
CGTCGAGCCGTGCCTGTTGTCGGAGGGGTATGACAAGCAGCACAGACGAAGACGAAACCGGACATCACGACCCCCATGGG
GTTCACTCGGGAGGAGTGGC

Downstream 100 bases:

>100_bases
GCGATGACGATGGCCGACACACAAATCCTCGCCGAGAAAAAACCAAGCGGCCCGATCGGGCGTTGGCTGACGATGTTGTG
GGCGGACAAGCTCGCTTTCT

Product: putative permease component of ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKSFIGKRAIASGVSLVVLIVIVFFLSRLTGDPTDLYLPIDATTEMRQQFREMNGFNDPLIIQFGRYVSDLAQGNFGQSL
RQARPAMDVVLEAFVWTFWLAVITMALVTVAAIVIGSLAAFRVGGVFDRLATFFSLIGAAAPDFWLAIVAIVIFAVKLHV
LPTSGTGTFWHWVLPVSVLFIRPFGLILQVVRGSMISVLSSAYVKTARAKGVRSNSIIFIHGLRNAMLPVITVIGDQAAA
ILNGAVVVETVFGFPGIGKLMIDSILLRDFAVVLAVIMVSALAIFIMNLLIDIAYALLDPRIRY

Sequences:

>Translated_304_residues
MKSFIGKRAIASGVSLVVLIVIVFFLSRLTGDPTDLYLPIDATTEMRQQFREMNGFNDPLIIQFGRYVSDLAQGNFGQSL
RQARPAMDVVLEAFVWTFWLAVITMALVTVAAIVIGSLAAFRVGGVFDRLATFFSLIGAAAPDFWLAIVAIVIFAVKLHV
LPTSGTGTFWHWVLPVSVLFIRPFGLILQVVRGSMISVLSSAYVKTARAKGVRSNSIIFIHGLRNAMLPVITVIGDQAAA
ILNGAVVVETVFGFPGIGKLMIDSILLRDFAVVLAVIMVSALAIFIMNLLIDIAYALLDPRIRY
>Mature_304_residues
MKSFIGKRAIASGVSLVVLIVIVFFLSRLTGDPTDLYLPIDATTEMRQQFREMNGFNDPLIIQFGRYVSDLAQGNFGQSL
RQARPAMDVVLEAFVWTFWLAVITMALVTVAAIVIGSLAAFRVGGVFDRLATFFSLIGAAAPDFWLAIVAIVIFAVKLHV
LPTSGTGTFWHWVLPVSVLFIRPFGLILQVVRGSMISVLSSAYVKTARAKGVRSNSIIFIHGLRNAMLPVITVIGDQAAA
ILNGAVVVETVFGFPGIGKLMIDSILLRDFAVVLAVIMVSALAIFIMNLLIDIAYALLDPRIRY

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=305, Percent_Identity=36.0655737704918, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1789965, Length=312, Percent_Identity=32.6923076923077, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1787497, Length=311, Percent_Identity=34.0836012861736, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789888, Length=288, Percent_Identity=32.6388888888889, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787761, Length=327, Percent_Identity=32.7217125382263, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788504, Length=280, Percent_Identity=28.2142857142857, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=27.5471698113208, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33107; Mature: 33107

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFIGKRAIASGVSLVVLIVIVFFLSRLTGDPTDLYLPIDATTEMRQQFREMNGFNDPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCCCH
IIQFGRYVSDLAQGNFGQSLRQARPAMDVVLEAFVWTFWLAVITMALVTVAAIVIGSLAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRVGGVFDRLATFFSLIGAAAPDFWLAIVAIVIFAVKLHVLPTSGTGTFWHWVLPVSVLF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
IRPFGLILQVVRGSMISVLSSAYVKTARAKGVRSNSIIFIHGLRNAMLPVITVIGDQAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHCCHHHH
ILNGAVVVETVFGFPGIGKLMIDSILLRDFAVVLAVIMVSALAIFIMNLLIDIAYALLDP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RIRY
CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]