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The map label for this gene is nanR [H]

Identifier: 116248898

GI number: 116248898

Start: 235660

End: 236394

Strand: Reverse

Name: nanR [H]

Synonym: pRL120228

Alternate gene names: 116248898

Gene position: 236394-235660 (Counterclockwise)

Preceding gene: 116248899

Following gene: 116248897

Centisome position: 27.17

GC content: 60.68

Gene sequence:

>735_bases
ATGGCGATGGATGTTCGGGCGATGCTCGAAGACGACGTTGCAACGCTTGGGGGAGCGCCGAAGAAGTCGATGAAAGACTT
CGTCGTCCAGAAGATTGCGACCTTCATCGCCACCGGCATCCTCAAAGCCGGCGACCCGCTGCCCAGCGAACGGGAGCTGG
CTTCCGCACTCTCGGTCAGCCGCGAGACCGTCCGTGGGGCGATCCTTATCCTTTCCACGCATGGGATTCTCTCGGTTGTG
CACGGAACGCGCACGGTGGTGGCATCGGAGGACGTCGGCGAATTGGCCGTCCAGGCTGCGCGGTATCGCGACATCGCGGC
CTACAGTCTCGACAATGTTCATGAGGCTCGGCTTCTTATCGAAGCACAGGTCGTCAGGGCCGCCGCGCTCAAGATGGAGC
CTGCAACTTTTGACTATCTCCGCAAGTCGATCGCAGCACAGGAAGCCGCCTGCGACGATCCCGTCCGTTTTTTGATCTGC
GACCGGGAATTTCACACCGCTATCTACCGTTCCAGCGGCAACGCGGTGCTGGCTGATATGGCCGCCGACCTCTATTCCTA
TCTTCTGAGCCACCGGAGGCGCGTCGTATCGCAGCCCGGGAGTATCGCCACGAGCATCGCCGATCACCGGTTGATCCTGG
CTGGTTTGGAGACGCGGGACCCGGATGCCGCATGCGCGGCCTTCGCAATCCACGAAACCCGTATTTATACGACGACCAAG
TTACTCTTCTCGTAG

Upstream 100 bases:

>100_bases
ATAACTGTGGAATCGATCGAGGACATCCAAGCGTTGACAATCTCTTGCCCCTGAGGTCTACTGGCCCACTTACCGGACCA
GCAGACCTCAGGGGGAGGGG

Downstream 100 bases:

>100_bases
TTCGCAGGGAGGCGAAACACGATGCACATTCTCATTATCGGGGCGGGAGGAATGATCGGCCGGAAGCTCGCCGCCACACT
GGGGCGCAGCGGGTCACTCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAMDVRAMLEDDVATLGGAPKKSMKDFVVQKIATFIATGILKAGDPLPSERELASALSVSRETVRGAILILSTHGILSVV
HGTRTVVASEDVGELAVQAARYRDIAAYSLDNVHEARLLIEAQVVRAAALKMEPATFDYLRKSIAAQEAACDDPVRFLIC
DREFHTAIYRSSGNAVLADMAADLYSYLLSHRRRVVSQPGSIATSIADHRLILAGLETRDPDAACAAFAIHETRIYTTTK
LLFS

Sequences:

>Translated_244_residues
MAMDVRAMLEDDVATLGGAPKKSMKDFVVQKIATFIATGILKAGDPLPSERELASALSVSRETVRGAILILSTHGILSVV
HGTRTVVASEDVGELAVQAARYRDIAAYSLDNVHEARLLIEAQVVRAAALKMEPATFDYLRKSIAAQEAACDDPVRFLIC
DREFHTAIYRSSGNAVLADMAADLYSYLLSHRRRVVSQPGSIATSIADHRLILAGLETRDPDAACAAFAIHETRIYTTTK
LLFS
>Mature_243_residues
AMDVRAMLEDDVATLGGAPKKSMKDFVVQKIATFIATGILKAGDPLPSERELASALSVSRETVRGAILILSTHGILSVVH
GTRTVVASEDVGELAVQAARYRDIAAYSLDNVHEARLLIEAQVVRAAALKMEPATFDYLRKSIAAQEAACDDPVRFLICD
REFHTAIYRSSGNAVLADMAADLYSYLLSHRRRVVSQPGSIATSIADHRLILAGLETRDPDAACAAFAIHETRIYTTTKL
LFS

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=226, Percent_Identity=26.1061946902655, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790032, Length=231, Percent_Identity=29.004329004329, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26431; Mature: 26299

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMDVRAMLEDDVATLGGAPKKSMKDFVVQKIATFIATGILKAGDPLPSERELASALSVS
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RETVRGAILILSTHGILSVVHGTRTVVASEDVGELAVQAARYRDIAAYSLDNVHEARLLI
HHHHHEEEEEEECCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EAQVVRAAALKMEPATFDYLRKSIAAQEAACDDPVRFLICDREFHTAIYRSSGNAVLADM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHEECCCCEEHHHH
AADLYSYLLSHRRRVVSQPGSIATSIADHRLILAGLETRDPDAACAAFAIHETRIYTTTK
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHEEEHHH
LLFS
HHCC
>Mature Secondary Structure 
AMDVRAMLEDDVATLGGAPKKSMKDFVVQKIATFIATGILKAGDPLPSERELASALSVS
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RETVRGAILILSTHGILSVVHGTRTVVASEDVGELAVQAARYRDIAAYSLDNVHEARLLI
HHHHHEEEEEEECCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
EAQVVRAAALKMEPATFDYLRKSIAAQEAACDDPVRFLICDREFHTAIYRSSGNAVLADM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHEECCCCEEHHHH
AADLYSYLLSHRRRVVSQPGSIATSIADHRLILAGLETRDPDAACAAFAIHETRIYTTTK
HHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHEEEHHH
LLFS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA