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The map label for this gene is yajO [H]

Identifier: 116248782

GI number: 116248782

Start: 101512

End: 102480

Strand: Direct

Name: yajO [H]

Synonym: pRL120106

Alternate gene names: 116248782

Gene position: 101512-102480 (Clockwise)

Preceding gene: 116248781

Following gene: 116248783

Centisome position: 11.67

GC content: 62.54

Gene sequence:

>969_bases
ATGAAGACCACAAGACTTGGCAAGACAGGGCTTGAAGTCAGCCGCATCTGCTTCGGCTGCATGTCCTTTGGCAAACAGAC
GGACGAACGCCCATGGGTTCTCGGGCTCGAAGAGGCGCGGCCACTCTATAAGCGCGCATGGGATGCCGGCATCAATTTCT
TCGATACGGCCAATGTCTACGCGCAGGGCACGAGCGAAGAGATCACCGGCGTCCTGCTCAAGGAACTGGCGCCCCGCCAA
GAGATCGTGCTGGCGACCAAGGTGTTCGGCCGCATGCGTCCCGGCCCGAACGGCCAGGGTCTTTCCCGCGCCGCGATCCT
TACCGAGATCGACAACAGCCTGCGCCGCCTCGGCACCGACTATATCGATCTCTACCAGATCCACCGCTTCGACCCGTTCA
CCCCGGTCGAAGAAACCATGCAGGCGCTAAACGACGTCGTGCGCGCCGGCAAGGCCCGCTATATCGGCGCATCCTCGATG
TGGGCCTGGCAGTTTTCCAAGCTCCAGCATGCAGCCGAGGTCAACGGCTGGACGAAGTTCGTTTCGATGCAGAACCAGGT
CAGCCTCACCTATCGCGAGGAAGAACGCGAAATGCTGCCGCTCTGCAGCGATCAGGGTATCGCCGTCCTTCCGTGGAGCC
CGCTTGCCGGCGGCAAGCTGACCCGTCCCTGGGGCACCGAGACCAAGCGCGCCACCACCGACCGCTACAACAAGAGCATG
TACGAGAAGACCGGCGATCGGGACGTCGTCGAGGCCGTCGAAGCCGTCGCCAAGGCGCGCAAGACGTCCATGGCGCAGGT
CGCGATGGCCTGGGTGCTGCAGAAGCCGGTCGTGACCTCGCCGATCGTCGGCGTCAGCAAGATGAGCCATCTCGAAGATG
CGATCGCCGCGGTCGACTTCGAACTCACCGGTGATGACGTCAAAGCGCTTGAAGCCCCCTACAAATCGCTGCACGTCGCC
GGTTTCTGA

Upstream 100 bases:

>100_bases
GGTTTCAAGGAAGAACACAACTGGCGGAAATACGTTTCCGGCGCATGATGCAGCGAGCCGCATTTGCGGCACCGCCGATC
AACAACTCGGAGGAAAGACC

Downstream 100 bases:

>100_bases
CGATAGCTCCGCGCGGGTTTTCAGACGCACAGTAACGTTTTGGATTGCGGCATAGGAAGAGATCATGACGAAAGAAGCAA
TGGTCGCTGGCATCCCGCAG

Product: putative short-chain aldo-keto oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKTTRLGKTGLEVSRICFGCMSFGKQTDERPWVLGLEEARPLYKRAWDAGINFFDTANVYAQGTSEEITGVLLKELAPRQ
EIVLATKVFGRMRPGPNGQGLSRAAILTEIDNSLRRLGTDYIDLYQIHRFDPFTPVEETMQALNDVVRAGKARYIGASSM
WAWQFSKLQHAAEVNGWTKFVSMQNQVSLTYREEEREMLPLCSDQGIAVLPWSPLAGGKLTRPWGTETKRATTDRYNKSM
YEKTGDRDVVEAVEAVAKARKTSMAQVAMAWVLQKPVVTSPIVGVSKMSHLEDAIAAVDFELTGDDVKALEAPYKSLHVA
GF

Sequences:

>Translated_322_residues
MKTTRLGKTGLEVSRICFGCMSFGKQTDERPWVLGLEEARPLYKRAWDAGINFFDTANVYAQGTSEEITGVLLKELAPRQ
EIVLATKVFGRMRPGPNGQGLSRAAILTEIDNSLRRLGTDYIDLYQIHRFDPFTPVEETMQALNDVVRAGKARYIGASSM
WAWQFSKLQHAAEVNGWTKFVSMQNQVSLTYREEEREMLPLCSDQGIAVLPWSPLAGGKLTRPWGTETKRATTDRYNKSM
YEKTGDRDVVEAVEAVAKARKTSMAQVAMAWVLQKPVVTSPIVGVSKMSHLEDAIAAVDFELTGDDVKALEAPYKSLHVA
GF
>Mature_322_residues
MKTTRLGKTGLEVSRICFGCMSFGKQTDERPWVLGLEEARPLYKRAWDAGINFFDTANVYAQGTSEEITGVLLKELAPRQ
EIVLATKVFGRMRPGPNGQGLSRAAILTEIDNSLRRLGTDYIDLYQIHRFDPFTPVEETMQALNDVVRAGKARYIGASSM
WAWQFSKLQHAAEVNGWTKFVSMQNQVSLTYREEEREMLPLCSDQGIAVLPWSPLAGGKLTRPWGTETKRATTDRYNKSM
YEKTGDRDVVEAVEAVAKARKTSMAQVAMAWVLQKPVVTSPIVGVSKMSHLEDAIAAVDFELTGDDVKALEAPYKSLHVA
GF

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=305, Percent_Identity=31.1475409836066, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4504825, Length=305, Percent_Identity=31.1475409836066, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=30.4487179487179, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=30, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=30.1282051282051, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=30.9677419354839, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI223718702, Length=266, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI41152114, Length=266, Percent_Identity=28.1954887218045, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41327764, Length=271, Percent_Identity=27.6752767527675, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=52, Blast_Score=345, Evalue=2e-96,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=30.6501547987616, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=29.5977011494253, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=30.9090909090909, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788081, Length=265, Percent_Identity=27.9245283018868, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI48994888, Length=312, Percent_Identity=27.8846153846154, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786400, Length=270, Percent_Identity=25.1851851851852, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=41.0557184750733, Blast_Score=245, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6319958, Length=287, Percent_Identity=31.3588850174216, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323998, Length=319, Percent_Identity=30.0940438871473, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319951, Length=313, Percent_Identity=28.4345047923323, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=29.8804780876494, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321052, Length=160, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320079, Length=273, Percent_Identity=24.9084249084249, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646155, Length=299, Percent_Identity=29.0969899665552, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24640980, Length=332, Percent_Identity=25.3012048192771, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646159, Length=182, Percent_Identity=35.7142857142857, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549126, Length=332, Percent_Identity=25.3012048192771, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35888; Mature: 35888

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTRLGKTGLEVSRICFGCMSFGKQTDERPWVLGLEEARPLYKRAWDAGINFFDTANVY
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCHHHHHHHHHCCCCEECCCCE
AQGTSEEITGVLLKELAPRQEIVLATKVFGRMRPGPNGQGLSRAAILTEIDNSLRRLGTD
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCH
YIDLYQIHRFDPFTPVEETMQALNDVVRAGKARYIGASSMWAWQFSKLQHAAEVNGWTKF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
VSMQNQVSLTYREEEREMLPLCSDQGIAVLPWSPLAGGKLTRPWGTETKRATTDRYNKSM
HHHCCCEEEEEEHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YEKTGDRDVVEAVEAVAKARKTSMAQVAMAWVLQKPVVTSPIVGVSKMSHLEDAIAAVDF
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEE
ELTGDDVKALEAPYKSLHVAGF
EECCCHHHHHHCCHHHEECCCC
>Mature Secondary Structure
MKTTRLGKTGLEVSRICFGCMSFGKQTDERPWVLGLEEARPLYKRAWDAGINFFDTANVY
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCHHHHHHHHHCCCCEECCCCE
AQGTSEEITGVLLKELAPRQEIVLATKVFGRMRPGPNGQGLSRAAILTEIDNSLRRLGTD
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCH
YIDLYQIHRFDPFTPVEETMQALNDVVRAGKARYIGASSMWAWQFSKLQHAAEVNGWTKF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
VSMQNQVSLTYREEEREMLPLCSDQGIAVLPWSPLAGGKLTRPWGTETKRATTDRYNKSM
HHHCCCEEEEEEHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YEKTGDRDVVEAVEAVAKARKTSMAQVAMAWVLQKPVVTSPIVGVSKMSHLEDAIAAVDF
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEE
ELTGDDVKALEAPYKSLHVAGF
EECCCHHHHHHCCHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]