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The map label for this gene is ygjG [C]

Identifier: 116248719

GI number: 116248719

Start: 42069

End: 43481

Strand: Reverse

Name: ygjG [C]

Synonym: pRL120043

Alternate gene names: 116248719

Gene position: 43481-42069 (Counterclockwise)

Preceding gene: 116248720

Following gene: 116248718

Centisome position: 5.0

GC content: 61.57

Gene sequence:

>1413_bases
GTGAGACCCTATTTTCAAGAAAGAGGCTACGACATGCTCGACAGAAGCAACGAACTCGCCGCCTGGGACCGCGATCACTT
CTTCCACCCCTCGACCCATATGGGCGGGCATGCCCGCGGCGAGACGCCGACCCGTGTCGTCGCCGGCGGCGAAGGCGTCT
ACATCACCGACACGACAGGCCGCAAAAGCCTCGACGCCTTTGCCGGTCTTTACTGCGTCAATGTCGGCTACGGCCGCCAG
AAGATAGCCGACGCGATCGCCGAGCAGGCAAAGAACCTTGCCTATTACCATGCCTATGTCGGCCACGGCACGGAAGCTTC
GATTACGCTGTCGAAGATGATTATCGACCGCGCCCCCACTGGCATGAGTCGCGTCTATTTCGGTCTCTCCGGCTCGGATG
CCAACGAGACCAACATTAAGCTCATCTGGTACTACAACAACATCCTCGGCCGTCCGGAAAAGAAAAAGATCATCTCGCGC
TGGCGCGGTTATCACGGCTCCGGCGTCATGACCGGCAGCCTCACCGGCCTTGCGCTCTTTCACAACGCTTTCGACCTGCC
GCGCGCACCCGTGCTGCACACCGAAGCACCCTATTATTTCCGCCGCCCCGACCGGTCGATGAGCGAGGAGCAGTTCTCGC
AATATTGCGCCGACAAGCTCGAGGAGATGATCATCGCCGAAGGCCCGGAAACGATCGCCGCCTTCATCGGCGAACCCATT
CTCGGCACCGGCGGCATCGTGCCGCCGCCGAAAAGCTACTGGCAGAAGATCCAGACCGTGCTCGACAAATATGACATCCT
GCTCGTCGCCGATGAAGTCGTCACCGGCTTCGGCCGTCTCGGCACGATGTTCGGCTCGGATCACTACGATATGAAGCCGG
ACGTGATCACCATCGCCAAGGGCCTGACCTCGGCCTACGCTCCCCTTTCCGGCACAATCGTTTCGAACAAGATTTGGCAA
GTCCTGGTGCAGGGTTCCGATCAGCTGGGCGCGATCGGTCACGGCTGGACCTATTCCGCCCATCCGATCTGTGCTGCCGC
AGGCATTGCCAATCTCGAACTGATCGATGAACTCGGGATTGTCGAGAATGCCGGCACGACCGGCGCCTATTTCCGCTCGG
AACTGGAGAAAGCCGTCAGCGGCCACCGGAACGTCGGCGAAGTCCGCGGCGACGGGCTGATGGCGGCCGTCGAATTCGTC
GACGACAAGGACGACCGCACGTTCTTCGACGCCGGCCGCAAGATCGGCCCGCAGGTTGCTTCCGCCCTTCTCGAACGCGG
TGTCATCGGCCGCGCCATGCCGCAGGGCGATATCCTCGGCTTCGCCCCGCCGCTCTGCCTGACACGCGAGGAGGCCGACA
TCGTGGTCAAGGCCGCGGCGGATGCGATCGAAACCGTCTTCAAGAACATCTGA

Upstream 100 bases:

>100_bases
AGCAGTCGGGTCTCGGCCGCGAAGGTTCACGCCATGGGCTCGAGGCCTTCACCGAGCTCAAATATCTCTGCATCGATACG
GCCGCCTGACCCCATTTCAA

Downstream 100 bases:

>100_bases
GGAAGAAGCTCAACATGACGATCCCGGAAAAGATGGCGGCGGTATTGCTCACCGGCCATGGCGGGTTGGACAAGCTCGTC
TATGACAGGGAGGTGCCCGT

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRPYFQERGYDMLDRSNELAAWDRDHFFHPSTHMGGHARGETPTRVVAGGEGVYITDTTGRKSLDAFAGLYCVNVGYGRQ
KIADAIAEQAKNLAYYHAYVGHGTEASITLSKMIIDRAPTGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISR
WRGYHGSGVMTGSLTGLALFHNAFDLPRAPVLHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMIIAEGPETIAAFIGEPI
LGTGGIVPPPKSYWQKIQTVLDKYDILLVADEVVTGFGRLGTMFGSDHYDMKPDVITIAKGLTSAYAPLSGTIVSNKIWQ
VLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGIVENAGTTGAYFRSELEKAVSGHRNVGEVRGDGLMAAVEFV
DDKDDRTFFDAGRKIGPQVASALLERGVIGRAMPQGDILGFAPPLCLTREEADIVVKAAADAIETVFKNI

Sequences:

>Translated_470_residues
MRPYFQERGYDMLDRSNELAAWDRDHFFHPSTHMGGHARGETPTRVVAGGEGVYITDTTGRKSLDAFAGLYCVNVGYGRQ
KIADAIAEQAKNLAYYHAYVGHGTEASITLSKMIIDRAPTGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISR
WRGYHGSGVMTGSLTGLALFHNAFDLPRAPVLHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMIIAEGPETIAAFIGEPI
LGTGGIVPPPKSYWQKIQTVLDKYDILLVADEVVTGFGRLGTMFGSDHYDMKPDVITIAKGLTSAYAPLSGTIVSNKIWQ
VLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGIVENAGTTGAYFRSELEKAVSGHRNVGEVRGDGLMAAVEFV
DDKDDRTFFDAGRKIGPQVASALLERGVIGRAMPQGDILGFAPPLCLTREEADIVVKAAADAIETVFKNI
>Mature_470_residues
MRPYFQERGYDMLDRSNELAAWDRDHFFHPSTHMGGHARGETPTRVVAGGEGVYITDTTGRKSLDAFAGLYCVNVGYGRQ
KIADAIAEQAKNLAYYHAYVGHGTEASITLSKMIIDRAPTGMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISR
WRGYHGSGVMTGSLTGLALFHNAFDLPRAPVLHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMIIAEGPETIAAFIGEPI
LGTGGIVPPPKSYWQKIQTVLDKYDILLVADEVVTGFGRLGTMFGSDHYDMKPDVITIAKGLTSAYAPLSGTIVSNKIWQ
VLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGIVENAGTTGAYFRSELEKAVSGHRNVGEVRGDGLMAAVEFV
DDKDDRTFFDAGRKIGPQVASALLERGVIGRAMPQGDILGFAPPLCLTREEADIVVKAAADAIETVFKNI

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=27.0454545454545, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4557809, Length=460, Percent_Identity=26.7391304347826, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI37574042, Length=434, Percent_Identity=25.8064516129032, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226442705, Length=436, Percent_Identity=26.605504587156, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI226442709, Length=358, Percent_Identity=27.6536312849162, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI284507298, Length=240, Percent_Identity=30.8333333333333, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=24.537037037037, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI145693181, Length=411, Percent_Identity=26.0340632603406, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1787560, Length=415, Percent_Identity=28.6746987951807, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=26.5356265356265, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=26.6826923076923, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789016, Length=356, Percent_Identity=26.123595505618, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786991, Length=464, Percent_Identity=26.0775862068966, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786349, Length=327, Percent_Identity=24.4648318042813, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32564660, Length=463, Percent_Identity=29.5896328293737, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25144271, Length=445, Percent_Identity=26.9662921348315, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=236, Percent_Identity=31.3559322033898, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71992977, Length=412, Percent_Identity=25.9708737864078, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=433, Percent_Identity=28.6374133949192, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324432, Length=420, Percent_Identity=24.7619047619048, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=365, Percent_Identity=24.3835616438356, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=370, Percent_Identity=25.9459459459459, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=29.1479820627803, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI161085790, Length=444, Percent_Identity=29.0540540540541, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21357415, Length=441, Percent_Identity=26.984126984127, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21356575, Length=423, Percent_Identity=24.113475177305, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281366494, Length=282, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667139, Length=282, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667143, Length=282, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 51330; Mature: 51330

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYFQERGYDMLDRSNELAAWDRDHFFHPSTHMGGHARGETPTRVVAGGEGVYITDTTG
CCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCC
RKSLDAFAGLYCVNVGYGRQKIADAIAEQAKNLAYYHAYVGHGTEASITLSKMIIDRAPT
CHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEHHHHHHHCCCC
GMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMTGSLTGLALF
CCCEEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHH
HNAFDLPRAPVLHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMIIAEGPETIAAFIGEPI
HHHHCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
LGTGGIVPPPKSYWQKIQTVLDKYDILLVADEVVTGFGRLGTMFGSDHYDMKPDVITIAK
CCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
GLTSAYAPLSGTIVSNKIWQVLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGI
HHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHCCC
VENAGTTGAYFRSELEKAVSGHRNVGEVRGDGLMAAVEFVDDKDDRTFFDAGRKIGPQVA
CCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEECCCCCCCHHHHHCCCCCHHHH
SALLERGVIGRAMPQGDILGFAPPLCLTREEADIVVKAAADAIETVFKNI
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPYFQERGYDMLDRSNELAAWDRDHFFHPSTHMGGHARGETPTRVVAGGEGVYITDTTG
CCCCHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCC
RKSLDAFAGLYCVNVGYGRQKIADAIAEQAKNLAYYHAYVGHGTEASITLSKMIIDRAPT
CHHHHHHHCEEEEECCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEHHHHHHHCCCC
GMSRVYFGLSGSDANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGVMTGSLTGLALF
CCCEEEEEECCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEECCHHHHHHH
HNAFDLPRAPVLHTEAPYYFRRPDRSMSEEQFSQYCADKLEEMIIAEGPETIAAFIGEPI
HHHHCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
LGTGGIVPPPKSYWQKIQTVLDKYDILLVADEVVTGFGRLGTMFGSDHYDMKPDVITIAK
CCCCCCCCCCHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
GLTSAYAPLSGTIVSNKIWQVLVQGSDQLGAIGHGWTYSAHPICAAAGIANLELIDELGI
HHHHHCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHCCC
VENAGTTGAYFRSELEKAVSGHRNVGEVRGDGLMAAVEFVDDKDDRTFFDAGRKIGPQVA
CCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCEEEEEECCCCCCCHHHHHCCCCCHHHH
SALLERGVIGRAMPQGDILGFAPPLCLTREEADIVVKAAADAIETVFKNI
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]