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The map label for this gene is yeiJ [C]

Identifier: 114800517

GI number: 114800517

Start: 2980743

End: 2982032

Strand: Reverse

Name: yeiJ [C]

Synonym: HNE_2817

Alternate gene names: 114800517

Gene position: 2982032-2980743 (Counterclockwise)

Preceding gene: 114798926

Following gene: 114799151

Centisome position: 80.49

GC content: 64.57

Gene sequence:

>1290_bases
ATGCCGGCAGGATATGAATGGGGCTGGGACAATGGGCGCGCGCTGATCGGCATCGCCCTGATCTATGGGCTGTGCTGGCT
CTTGTCCGAAAAACGCAAACTCTTCCCCTGGAAGATCGTGCTCGGCGCCACGGCCATGCAGTTTGCCTTCGCGCTCATCC
TGTTCGGCATTCCCTTCATCAAGGACATCCTCCTGGCCGCCAACGGCCTCGTCGATGGCCTCCAGAACGCCACCCGCGCG
GGCACCAGTTTCGTCTTCGGCTATGTCGGGGATAATGTCGCTGCCAGCGAAGTCATCGGCGGCTCCCCACCACCGCTGTT
CTTCTTCCAGATCCTGCCCATCATCATCGTCGTGGCGGCCCTCTCGGCCATCCTCTGGCACTGGCATATCCTGCGCTGGA
TCACCAACGGCTTTGCCTTCGTCTTCCGGCGCGGCATGGGCCTGGGCGGGGCCACCTCGCTCGCCGTCTCCGCCAACGTC
TTCATGGGCATGACCGAAGCCCCCGTCCTCATCCGGCCTTACATCAAAGGCATGACGCGCTCTGAGCTGCTCATCATGAT
GACCGCCGGCTTTGCCACCATCGCCGGCTCGGTCCTCGTCGTCTATGGCGCCTTCCTGGAAGGCAAGATGGCCAATCCGC
TGCCCCAGCTTCTGGCCGCCTCAATCATCGCTGCGCCCGCCGCCGTCGGCGTCGCCCTCGCCATGATCCCGGAAACCACC
CCGGTGTCGGAGCGGATGAAAGACCCCGATTTCAAATACGCCTCCACCATGGACGCCTTCTCCACCGGCGCCACCGATGG
CCTGAAGATCGTCTTCAACATCGCCACCATGCTGATCGCGGCCCTGGCGCTGCTCTGGCTGGTCAATGCCGGCCTCGGCG
CCTTCCCGGATGTGAACGGCGCGCCGCTCTCCATCGAGCGTATCCTCGGCTGGATCTTCGCGCCCCTGATGTACATGATC
GGTGTGCCCTGGAGCGAAGCCTCCCAGTCCGGCTCATTGATGGGCGTGAAAACCGTGCTGACCGAATTCGTCGCCTTCCT
CCAACTCGCCGAACTCCCCGTCGAAGCGATGGACCCGCGCACACGGATGATCACCGCCCACGCCATCTGCGGCTTTGCCA
ATTTCGGCTCGATGGGCATCCTCATCGGCGGCCTGACGATTGTTGAGCCTGAGCGCCGGGATGACTTCCTCAGCCTCGCC
TGGCGCACCCTGCTGGCCGGCACGCTGGCCACCTGCCTCTCCGGCGCCGTCGTCGGCGCGCTGCCCTACGCCCTGTTCGC
GGGCGGCTGA

Upstream 100 bases:

>100_bases
GCGCTCTCCCGATCCGCAATTGCCATTCCCGCTTTCCAAGCCTTTCCCCGCCCGTTAAGTCTCAACGCTTGGGTCTGATT
TGCGGGAGGGCTGACGCAAC

Downstream 100 bases:

>100_bases
CGCAGCGGCCGGGGTCGCCATCGGCCCCGGCAGGCCCTAGATGTGACGCGGGTGAGGGCAACCGCCGCGCCCTGAAAACA
GGGAGCGTAGATTTGCCTTA

Product: NupC family nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MPAGYEWGWDNGRALIGIALIYGLCWLLSEKRKLFPWKIVLGATAMQFAFALILFGIPFIKDILLAANGLVDGLQNATRA
GTSFVFGYVGDNVAASEVIGGSPPPLFFFQILPIIIVVAALSAILWHWHILRWITNGFAFVFRRGMGLGGATSLAVSANV
FMGMTEAPVLIRPYIKGMTRSELLIMMTAGFATIAGSVLVVYGAFLEGKMANPLPQLLAASIIAAPAAVGVALAMIPETT
PVSERMKDPDFKYASTMDAFSTGATDGLKIVFNIATMLIAALALLWLVNAGLGAFPDVNGAPLSIERILGWIFAPLMYMI
GVPWSEASQSGSLMGVKTVLTEFVAFLQLAELPVEAMDPRTRMITAHAICGFANFGSMGILIGGLTIVEPERRDDFLSLA
WRTLLAGTLATCLSGAVVGALPYALFAGG

Sequences:

>Translated_429_residues
MPAGYEWGWDNGRALIGIALIYGLCWLLSEKRKLFPWKIVLGATAMQFAFALILFGIPFIKDILLAANGLVDGLQNATRA
GTSFVFGYVGDNVAASEVIGGSPPPLFFFQILPIIIVVAALSAILWHWHILRWITNGFAFVFRRGMGLGGATSLAVSANV
FMGMTEAPVLIRPYIKGMTRSELLIMMTAGFATIAGSVLVVYGAFLEGKMANPLPQLLAASIIAAPAAVGVALAMIPETT
PVSERMKDPDFKYASTMDAFSTGATDGLKIVFNIATMLIAALALLWLVNAGLGAFPDVNGAPLSIERILGWIFAPLMYMI
GVPWSEASQSGSLMGVKTVLTEFVAFLQLAELPVEAMDPRTRMITAHAICGFANFGSMGILIGGLTIVEPERRDDFLSLA
WRTLLAGTLATCLSGAVVGALPYALFAGG
>Mature_428_residues
PAGYEWGWDNGRALIGIALIYGLCWLLSEKRKLFPWKIVLGATAMQFAFALILFGIPFIKDILLAANGLVDGLQNATRAG
TSFVFGYVGDNVAASEVIGGSPPPLFFFQILPIIIVVAALSAILWHWHILRWITNGFAFVFRRGMGLGGATSLAVSANVF
MGMTEAPVLIRPYIKGMTRSELLIMMTAGFATIAGSVLVVYGAFLEGKMANPLPQLLAASIIAAPAAVGVALAMIPETTP
VSERMKDPDFKYASTMDAFSTGATDGLKIVFNIATMLIAALALLWLVNAGLGAFPDVNGAPLSIERILGWIFAPLMYMIG
VPWSEASQSGSLMGVKTVLTEFVAFLQLAELPVEAMDPRTRMITAHAICGFANFGSMGILIGGLTIVEPERRDDFLSLAW
RTLLAGTLATCLSGAVVGALPYALFAGG

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=426, Percent_Identity=32.1596244131455, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI42542381, Length=430, Percent_Identity=33.0232558139535, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI11545853, Length=363, Percent_Identity=36.0881542699724, Blast_Score=201, Evalue=8e-52,
Organism=Escherichia coli, GI1788485, Length=417, Percent_Identity=30.6954436450839, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1788488, Length=417, Percent_Identity=30.9352517985612, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1788737, Length=411, Percent_Identity=25.3041362530414, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17560276, Length=405, Percent_Identity=29.3827160493827, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI71991794, Length=406, Percent_Identity=28.8177339901478, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25146537, Length=210, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281360430, Length=436, Percent_Identity=31.8807339449541, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI45552519, Length=407, Percent_Identity=30.4668304668305, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI45552517, Length=407, Percent_Identity=30.4668304668305, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI19921868, Length=407, Percent_Identity=30.4668304668305, Blast_Score=178, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 45621; Mature: 45489

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGYEWGWDNGRALIGIALIYGLCWLLSEKRKLFPWKIVLGATAMQFAFALILFGIPFI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KDILLAANGLVDGLQNATRAGTSFVFGYVGDNVAASEVIGGSPPPLFFFQILPIIIVVAA
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LSAILWHWHILRWITNGFAFVFRRGMGLGGATSLAVSANVFMGMTEAPVLIRPYIKGMTR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
SELLIMMTAGFATIAGSVLVVYGAFLEGKMANPLPQLLAASIIAAPAAVGVALAMIPETT
CCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVSERMKDPDFKYASTMDAFSTGATDGLKIVFNIATMLIAALALLWLVNAGLGAFPDVNG
CHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
APLSIERILGWIFAPLMYMIGVPWSEASQSGSLMGVKTVLTEFVAFLQLAELPVEAMDPR
CCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCH
TRMITAHAICGFANFGSMGILIGGLTIVEPERRDDFLSLAWRTLLAGTLATCLSGAVVGA
HHEEHHHHHHHHHCCCCCHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYALFAGG
HHHHHHCCC
>Mature Secondary Structure 
PAGYEWGWDNGRALIGIALIYGLCWLLSEKRKLFPWKIVLGATAMQFAFALILFGIPFI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KDILLAANGLVDGLQNATRAGTSFVFGYVGDNVAASEVIGGSPPPLFFFQILPIIIVVAA
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LSAILWHWHILRWITNGFAFVFRRGMGLGGATSLAVSANVFMGMTEAPVLIRPYIKGMTR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
SELLIMMTAGFATIAGSVLVVYGAFLEGKMANPLPQLLAASIIAAPAAVGVALAMIPETT
CCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVSERMKDPDFKYASTMDAFSTGATDGLKIVFNIATMLIAALALLWLVNAGLGAFPDVNG
CHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
APLSIERILGWIFAPLMYMIGVPWSEASQSGSLMGVKTVLTEFVAFLQLAELPVEAMDPR
CCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCH
TRMITAHAICGFANFGSMGILIGGLTIVEPERRDDFLSLAWRTLLAGTLATCLSGAVVGA
HHEEHHHHHHHHHCCCCCHHEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYALFAGG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]