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The map label for this gene is ttdR [H]

Identifier: 114800444

GI number: 114800444

Start: 1134768

End: 1135748

Strand: Direct

Name: ttdR [H]

Synonym: HNE_1123

Alternate gene names: 114800444

Gene position: 1134768-1135748 (Clockwise)

Preceding gene: 114798036

Following gene: 114799119

Centisome position: 30.63

GC content: 61.16

Gene sequence:

>981_bases
ATGAACACGGATCGGCTCGACTGGGATACGCTGCGCGTGTTCCGTGTTGTCGCGGAACTGAGCAGCATGAGCGGCGCAGC
GGCGCGCCTGGGCGAATCCCCGCCCACCATCAGCCGCAAGATTGATGACCTTGAAACGACCATCGGCGCCCAGCTGTTCG
TCCGCTCCACGCGCGGCGTGGAATTGACCGAAGCGGGCAAGGTTGTGCTGCGCTACGCCCACCAGATGGCGGAAGCGGCC
AATACACTACGCGATGAAGCCGGCGCCCAGCGCGCGCCCGTTGAAGGCCGCATCACCATCTCCACCGGCGATGGCATCGG
CCCTTACTGGCTCGCCCCGCGCCTGCACGAATTTCAGGATATGAACCCGCGCATCCAGATCCGCATGATCGTCAATGATG
ATCCCGCCGATGTGACCAATGGCGACGCGGACATCGCAATCCATTTTTCCGAACCCAAGAGCCATGAGCTGCTGACCCAC
CGGCTGGGCGTTCAACACTATATCGGGTTTGCCTCGAAGGATTATTTCCGGGAGCGCAAGCCGCCGGAAAGCCTGTTTGA
ATATTATAAATACCGCTGCCTGATGCACTCTTCCTATGTGAACCAGGTAGAGCGCTGGGCGCCTAAAGTGTCCGAGCTGC
GCCGGATGATCGATTATGCCTTCGTGTCGAATTCCGGAACGGCGCTGATCCAGTCCTGCGCGGCGGGCGGCGGCGTGGCG
ATCCTGCCCTCCTTCATTGCGGCCATGGATAATCGTCTCATTCCGCTGGACCTGCCGGAAATTGCGCCGATCCAGTTCTG
GGTTGCCTATACCGAGCGTTTCCGCCGGCGGCCGGAGGGGCAGCCCTTCGTCGACTGGATACGCAAACGCTTCGAGCAGG
ATGACGCGATGTGGTTCCGCGAACAGTTCGTCCATCCCAGAGACGTGTTTTCCAACGTCCACATCTTCCCCGGCGTTGCC
GGAACCCGCCGCGAATCCTGA

Upstream 100 bases:

>100_bases
GTTTTGCGCCAGCACTGAGCAAATCAATTGCAGGGCGATAACCGGCAGGCTATTTCCCTGAGTCTGTTTTCGGGATCAAC
AATTGGCTGGGTAGCGGCGC

Downstream 100 bases:

>100_bases
TTGCCGCGTTGTGCCCCGGCGCCATTGCGCAGGAGCAAGCAGGCGTCTTATGATCCGCGCCATTGGTAATCTGGCAGCGG
TAACGGGCCGAGGGGGATAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNTDRLDWDTLRVFRVVAELSSMSGAAARLGESPPTISRKIDDLETTIGAQLFVRSTRGVELTEAGKVVLRYAHQMAEAA
NTLRDEAGAQRAPVEGRITISTGDGIGPYWLAPRLHEFQDMNPRIQIRMIVNDDPADVTNGDADIAIHFSEPKSHELLTH
RLGVQHYIGFASKDYFRERKPPESLFEYYKYRCLMHSSYVNQVERWAPKVSELRRMIDYAFVSNSGTALIQSCAAGGGVA
ILPSFIAAMDNRLIPLDLPEIAPIQFWVAYTERFRRRPEGQPFVDWIRKRFEQDDAMWFREQFVHPRDVFSNVHIFPGVA
GTRRES

Sequences:

>Translated_326_residues
MNTDRLDWDTLRVFRVVAELSSMSGAAARLGESPPTISRKIDDLETTIGAQLFVRSTRGVELTEAGKVVLRYAHQMAEAA
NTLRDEAGAQRAPVEGRITISTGDGIGPYWLAPRLHEFQDMNPRIQIRMIVNDDPADVTNGDADIAIHFSEPKSHELLTH
RLGVQHYIGFASKDYFRERKPPESLFEYYKYRCLMHSSYVNQVERWAPKVSELRRMIDYAFVSNSGTALIQSCAAGGGVA
ILPSFIAAMDNRLIPLDLPEIAPIQFWVAYTERFRRRPEGQPFVDWIRKRFEQDDAMWFREQFVHPRDVFSNVHIFPGVA
GTRRES
>Mature_326_residues
MNTDRLDWDTLRVFRVVAELSSMSGAAARLGESPPTISRKIDDLETTIGAQLFVRSTRGVELTEAGKVVLRYAHQMAEAA
NTLRDEAGAQRAPVEGRITISTGDGIGPYWLAPRLHEFQDMNPRIQIRMIVNDDPADVTNGDADIAIHFSEPKSHELLTH
RLGVQHYIGFASKDYFRERKPPESLFEYYKYRCLMHSSYVNQVERWAPKVSELRRMIDYAFVSNSGTALIQSCAAGGGVA
ILPSFIAAMDNRLIPLDLPEIAPIQFWVAYTERFRRRPEGQPFVDWIRKRFEQDDAMWFREQFVHPRDVFSNVHIFPGVA
GTRRES

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=24.8299319727891, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=26.3698630136986, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786401, Length=308, Percent_Identity=23.0519480519481, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788706, Length=198, Percent_Identity=27.7777777777778, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789639, Length=234, Percent_Identity=24.7863247863248, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786448, Length=185, Percent_Identity=27.5675675675676, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790011, Length=296, Percent_Identity=22.972972972973, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI145693193, Length=174, Percent_Identity=28.735632183908, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=166, Percent_Identity=25.9036144578313, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787589, Length=241, Percent_Identity=26.5560165975104, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789173, Length=246, Percent_Identity=24.7967479674797, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37160; Mature: 37160

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDRLDWDTLRVFRVVAELSSMSGAAARLGESPPTISRKIDDLETTIGAQLFVRSTRGV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCC
ELTEAGKVVLRYAHQMAEAANTLRDEAGAQRAPVEGRITISTGDGIGPYWLAPRLHEFQD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHCCHHHHHHC
MNPRIQIRMIVNDDPADVTNGDADIAIHFSEPKSHELLTHRLGVQHYIGFASKDYFRERK
CCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPESLFEYYKYRCLMHSSYVNQVERWAPKVSELRRMIDYAFVSNSGTALIQSCAAGGGVA
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHH
ILPSFIAAMDNRLIPLDLPEIAPIQFWVAYTERFRRRPEGQPFVDWIRKRFEQDDAMWFR
HHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHH
EQFVHPRDVFSNVHIFPGVAGTRRES
HHCCCHHHHHCCCEECCCCCCCCCCC
>Mature Secondary Structure
MNTDRLDWDTLRVFRVVAELSSMSGAAARLGESPPTISRKIDDLETTIGAQLFVRSTRGV
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHEEECCCCC
ELTEAGKVVLRYAHQMAEAANTLRDEAGAQRAPVEGRITISTGDGIGPYWLAPRLHEFQD
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHCCHHHHHHC
MNPRIQIRMIVNDDPADVTNGDADIAIHFSEPKSHELLTHRLGVQHYIGFASKDYFRERK
CCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPESLFEYYKYRCLMHSSYVNQVERWAPKVSELRRMIDYAFVSNSGTALIQSCAAGGGVA
CHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHH
ILPSFIAAMDNRLIPLDLPEIAPIQFWVAYTERFRRRPEGQPFVDWIRKRFEQDDAMWFR
HHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHH
EQFVHPRDVFSNVHIFPGVAGTRRES
HHCCCHHHHHCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]