Click here to switch to the map view.

The map label for this gene is acoC [H]

Identifier: 114800369

GI number: 114800369

Start: 3571899

End: 3572900

Strand: Direct

Name: acoC [H]

Synonym: HNE_3432

Alternate gene names: 114800369

Gene position: 3571899-3572900 (Clockwise)

Preceding gene: 114797177

Following gene: 114797532

Centisome position: 96.41

GC content: 63.67

Gene sequence:

>1002_bases
ATGTTGTCCCGCTTTCTCGCTGTTATCCTCACGCTCGGCGTCATCCTGTTCGCAGGCTGGTGGTCTTTGAAGCGGGATGA
CATACCCTACGACCAGCTGGAAACCATCTATGCCAATTCCGACAGCCGGTATCTGGCGCTCGATGATGAAAAGCGGATCC
ATTTCCGGGATGTCGGCCCGCGCGACGCGCCTGCCATCATTCTCGTGCACGGCTTTTCCGCCTCGCTGCACACATGGGAA
CCCTGGGTGACAGATCTTAAACGCGACTATCGCGTCATCAGCCTCGACCTGCCCGGCCATGGCCTCTCCCGCTGCCTCGA
CAATGACGCCATCGGCATGGATCAGTTCGTGGATGTCATCTACCGCGTGGCCAGCGCGCTGAAGGTCGACCGCTTCACGC
TCGCCGGAAACTCCATGGGCGGCGGCGCGGCCTGGAATTATGCCCTCGCCCATCCTGAGCGCCTGGACGGCCTCGTGCTG
GTCGATGCCGCCGGCTGGCCCCGCACGGAAGGCGAGAGCGATGACCGGCCCTTCGTGTTCCGCCTTCTGGAAATCGGCAT
CGCGCGCAAGCTGGTCAAGGATCTCGACATGTCCTCGCTGATCCGCCCCGGCCTGGAAGACAGTTTCTCTGACCCCTCCT
TTGTGACCGACGAGATGGTGGACCGCTATGGCTCGCTGGCGCGCGCGCCCTGCCATCGTGAAGCACTGCTGGCCCTCTCT
GCCGGGCGCGGCACCCGCGCCGAAGCGACACCCGAGCTTCTTTCCGCGATCACAACGCCCACACTGGTGATGCATGGCGA
GCAGGACAACGTCATCCCCTTCTCCCATGGCGAGCAGTTTGCCGCCGCCATCCCCGGCGCAGAGCTCAAACTCTATCCGA
ATGTCGGCCACCTCCCGCAGGAAGAAATCGCCGCCCAGTCGCTGGAAGATCTGCGGGCTTTTCTGACAGCCCGCGTCCAC
GGCGCAGCCCCCGCCAGCGAGAGCGAGCTACCGACCAACTGA

Upstream 100 bases:

>100_bases
TCAGTGTCCTGTCTGTTCCATCTGAACAGAAGGTTTGACATGCGCGCCAGCGCGCGCGTTATTCGCGAAGCAGTTTTGTT
GATCGGATTCTTCGCCTCAG

Downstream 100 bases:

>100_bases
GCTTTCAGTTTCAGCCCGTCTGCTGAAGATCAGAGGATCGCGGGGATCACACGGTCTGGCGGCCGGTGGCCGTCAGCGAA
GGTCTTGATATTGATGATGA

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLSRFLAVILTLGVILFAGWWSLKRDDIPYDQLETIYANSDSRYLALDDEKRIHFRDVGPRDAPAIILVHGFSASLHTWE
PWVTDLKRDYRVISLDLPGHGLSRCLDNDAIGMDQFVDVIYRVASALKVDRFTLAGNSMGGGAAWNYALAHPERLDGLVL
VDAAGWPRTEGESDDRPFVFRLLEIGIARKLVKDLDMSSLIRPGLEDSFSDPSFVTDEMVDRYGSLARAPCHREALLALS
AGRGTRAEATPELLSAITTPTLVMHGEQDNVIPFSHGEQFAAAIPGAELKLYPNVGHLPQEEIAAQSLEDLRAFLTARVH
GAAPASESELPTN

Sequences:

>Translated_333_residues
MLSRFLAVILTLGVILFAGWWSLKRDDIPYDQLETIYANSDSRYLALDDEKRIHFRDVGPRDAPAIILVHGFSASLHTWE
PWVTDLKRDYRVISLDLPGHGLSRCLDNDAIGMDQFVDVIYRVASALKVDRFTLAGNSMGGGAAWNYALAHPERLDGLVL
VDAAGWPRTEGESDDRPFVFRLLEIGIARKLVKDLDMSSLIRPGLEDSFSDPSFVTDEMVDRYGSLARAPCHREALLALS
AGRGTRAEATPELLSAITTPTLVMHGEQDNVIPFSHGEQFAAAIPGAELKLYPNVGHLPQEEIAAQSLEDLRAFLTARVH
GAAPASESELPTN
>Mature_333_residues
MLSRFLAVILTLGVILFAGWWSLKRDDIPYDQLETIYANSDSRYLALDDEKRIHFRDVGPRDAPAIILVHGFSASLHTWE
PWVTDLKRDYRVISLDLPGHGLSRCLDNDAIGMDQFVDVIYRVASALKVDRFTLAGNSMGGGAAWNYALAHPERLDGLVL
VDAAGWPRTEGESDDRPFVFRLLEIGIARKLVKDLDMSSLIRPGLEDSFSDPSFVTDEMVDRYGSLARAPCHREALLALS
AGRGTRAEATPELLSAITTPTLVMHGEQDNVIPFSHGEQFAAAIPGAELKLYPNVGHLPQEEIAAQSLEDLRAFLTARVH
GAAPASESELPTN

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=267, Percent_Identity=26.9662921348315, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081721, Length=274, Percent_Identity=28.4671532846715, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 36659; Mature: 36659

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRFLAVILTLGVILFAGWWSLKRDDIPYDQLETIYANSDSRYLALDDEKRIHFRDVGP
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCCCCEEEECCCCCEEEECCCC
RDAPAIILVHGFSASLHTWEPWVTDLKRDYRVISLDLPGHGLSRCLDNDAIGMDQFVDVI
CCCCEEEEEECCCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHH
YRVASALKVDRFTLAGNSMGGGAAWNYALAHPERLDGLVLVDAAGWPRTEGESDDRPFVF
HHHHHHHHHHEEEEECCCCCCCCCCCHHHCCHHHCCCEEEEECCCCCCCCCCCCCCHHHH
RLLEIGIARKLVKDLDMSSLIRPGLEDSFSDPSFVTDEMVDRYGSLARAPCHREALLALS
HHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHEEE
AGRGTRAEATPELLSAITTPTLVMHGEQDNVIPFSHGEQFAAAIPGAELKLYPNVGHLPQ
CCCCCCCCCCHHHHHHHCCCEEEEECCCCCEEECCCCCHHHHHCCCCEEEECCCCCCCCH
EEIAAQSLEDLRAFLTARVHGAAPASESELPTN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSRFLAVILTLGVILFAGWWSLKRDDIPYDQLETIYANSDSRYLALDDEKRIHFRDVGP
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEEECCCCCEEEECCCCCEEEECCCC
RDAPAIILVHGFSASLHTWEPWVTDLKRDYRVISLDLPGHGLSRCLDNDAIGMDQFVDVI
CCCCEEEEEECCCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCCHHHHHHHH
YRVASALKVDRFTLAGNSMGGGAAWNYALAHPERLDGLVLVDAAGWPRTEGESDDRPFVF
HHHHHHHHHHEEEEECCCCCCCCCCCHHHCCHHHCCCEEEEECCCCCCCCCCCCCCHHHH
RLLEIGIARKLVKDLDMSSLIRPGLEDSFSDPSFVTDEMVDRYGSLARAPCHREALLALS
HHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHEEE
AGRGTRAEATPELLSAITTPTLVMHGEQDNVIPFSHGEQFAAAIPGAELKLYPNVGHLPQ
CCCCCCCCCCHHHHHHHCCCEEEEECCCCCEEECCCCCHHHHHCCCCEEEECCCCCCCCH
EEIAAQSLEDLRAFLTARVHGAAPASESELPTN
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]