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The map label for this gene is ntrY [H]

Identifier: 114800247

GI number: 114800247

Start: 2085712

End: 2087991

Strand: Reverse

Name: ntrY [H]

Synonym: HNE_2010

Alternate gene names: 114800247

Gene position: 2087991-2085712 (Counterclockwise)

Preceding gene: 114799444

Following gene: 114799003

Centisome position: 56.36

GC content: 62.85

Gene sequence:

>2280_bases
GTGTCGACGACCGCAGCTAACTCTCAGGCCAACAAGGCAAGCTGGGCCCTGTTTGAAGGGCTCTTCATCATTGCGGCCCT
GGTCGCGGTGTTTGCGACCTTTATTGCCATTTCCGGGGTCGTTCCCGACGATCCGACGGCGGGCGCAACGCCCTGGCTGC
TCGGCCTGAACTTCATTCTCCTCATCGTACTCGCCATCATCGTAACGCGCGAATACCTGCAGATCCGCGTCGGCAAGGAA
GATGGCAGTGGCAAACTCGCCCGCCGGTTCGTGCTGCTGTTCGGTTTCTCGGCGCTGATCCCGGCGATGGTCGTGGCCGT
GTTCATGGGCACCTTCATCACGCGCGGCCTGGACCGCTGGCTGGGCGAACGGGTCGACCATCTGATGGAACAGAATGCGG
AAATCTTCCGCACCTATGTCGAAAACTTCCAGGCGACCTTTGATTCCGACATGCGCCTCGCAGCGCTCGACGTGGAAAGC
TTCGCCCGCCAGGTGGACCAGAGCCTCGCCATTGCCCCGCCCACCGAAGATGGGGACGGGGCCATCTATGACTATGCCTC
CACCACCTTCTTCGACGGTCTGCGCTCCGAACTGGCCAGCCGCGAGTTTCTCACCATCGCCATTCTCGGCGCAGACGGGG
TCGATCTCGTTGCCGAAGCGAGCGTTCAGGAACCCATTCTCCTGCTGCCACCCAAGTCAGCCTATCTCGAGGCCGATGAA
GGCGCGGTGGCGACCACGCTCTATGAGGGCCGCGGCCTTGCAACGGCGCTCATTCGCATCTCCGCGCCCACGGACGGCTA
TATCTATGCCGTGAAGGTGTTCGACCGGAACGCGGCGCGCTCGCTGCGTGAAGCCGAAGCCGCGCTTGAAGAATACTACG
CCGCTAAACGAAGCGGCGGCCGGCTGCAAATCATCTTCGTGATCGGCTATGCCCAGATTGCCGGCCTGGTTCTGTTGCTG
GCCGGGCGTCTTGGCCTGGAGGCAGCCGGGCGCGTGACGGGCCCCATCGGGCGCCTCGCATCGGCCGCGCATACCGTGCG
CGACGGCGATCTCAGTGTCCGCGTGCCGGTCTCCGGCCCGGTCGACGAATTGCATGCGCTGGGCCATTCATTCAACGCCA
TGACCGAGCAGCTAGCCAACCAGCGCGAAGCGCTCATCCGCGCCCGGAATGACGAAGAAGACCGGCGCCGGTTTGTCGAG
ACGCTGTTGGCCGAACTGGGCGCGGGGGTGATGCGCGTCGGCCCCGATGGCATGATAAGCTTGGCCAACCGGTCGGCCGC
TGAAATGCTGGGCCTGCCAGGAATTGACGAAGGCGCGCCGCTCTCGTCGGTCGCGCCGGAGTTTGAGCGGTATGTCCGCG
ATACGATCGAGCGTGACGCGCCGGTCGATGCGACGCTGGACCTCAGCATCGGCGGAGAGACGCGCAACATCCGCCTCAAG
ACAGCGCTTGGTCCTGAAGGCGGCTGCGTGATCACATTTGACGATACCACCCGGCTCGTGAACGCCCAGCGCCAGCTCGC
ATGGCGCGATGTGGCCCGCCGGATTGCCCATGAAATCCGCAACCCCCTGACGCCGATCATGCTGTCTACGGAACGTCTCA
AGCGCCGCTACGGGCCGAAAATCGACGATCCCGACGGTGTGTTTGACCGCTGCATCGAGACGATCCTGCGCAAGGTGGAT
GACATCGCTCGCATGGTGGAGGAATTCTCCTCGTTCGCCCGGATGCCCAAGCCCAGCGTCGCCCCGTTTGACATGCGCGA
CCTGTTGCAGGAGGCAATCTTCTCGCAGAGCGTTGTCTCCCCTGACATCGATATAATGCTGGAAACAGACCTCAAGACCG
CGCCCTATCTCGGGGATGACCGCCTGCTTGGCCAGGCGTTCGGAAACCTCCTCAAGAATGCGGCAGAAGCCATTGAGGGG
CAGCCCATCGAACATGATGTGTCCGGGCATATCCGGATCATTCTCCAGCAGGAAGTCCGTGGGCTGGAAATCATCATAGA
AGACAATGGCCCCGGCTTTCCGGCTGAAGTCCGCAACCGGCTGCTCGAGCCCTATGTGACAACGCGGGAGAAGGGGACAG
GCCTTGGCCTGGCCATCGTGAACCGCATCATCGTCGATCATGGCGGCTCCATTTCCCTTCAGAACCGGCCCGACGGACTG
CGCGGCGCCCGTGTGCGTGTGGTCCTGCCGGAGAACGGCGCGCTGGTGATGCAGTCAGAAGACAATTCCGCAGACGAGGT
GGGCGGGACTGACCGCTTACCTTATCCCTTGAGTTTGTAG

Upstream 100 bases:

>100_bases
GACACCCCAATCTGTGGCTCAAGTGCACCACTGTTGCTGGCAGGACACTTAACTGTGTCCTGATTGCAACGGGGCGGGGC
CCCAACAGAGCCGGAATTGA

Downstream 100 bases:

>100_bases
AGGAGAGTAGCGCATGGCACTCGACATCCTGGTAGTGGACGATGAGCCTGACATCCGTGAGCTGATGGCAGGTGTCCTCG
GCGACGAAGGTTATGCTGTC

Product: nitrogen regulation protein NtrY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MSTTAANSQANKASWALFEGLFIIAALVAVFATFIAISGVVPDDPTAGATPWLLGLNFILLIVLAIIVTREYLQIRVGKE
DGSGKLARRFVLLFGFSALIPAMVVAVFMGTFITRGLDRWLGERVDHLMEQNAEIFRTYVENFQATFDSDMRLAALDVES
FARQVDQSLAIAPPTEDGDGAIYDYASTTFFDGLRSELASREFLTIAILGADGVDLVAEASVQEPILLLPPKSAYLEADE
GAVATTLYEGRGLATALIRISAPTDGYIYAVKVFDRNAARSLREAEAALEEYYAAKRSGGRLQIIFVIGYAQIAGLVLLL
AGRLGLEAAGRVTGPIGRLASAAHTVRDGDLSVRVPVSGPVDELHALGHSFNAMTEQLANQREALIRARNDEEDRRRFVE
TLLAELGAGVMRVGPDGMISLANRSAAEMLGLPGIDEGAPLSSVAPEFERYVRDTIERDAPVDATLDLSIGGETRNIRLK
TALGPEGGCVITFDDTTRLVNAQRQLAWRDVARRIAHEIRNPLTPIMLSTERLKRRYGPKIDDPDGVFDRCIETILRKVD
DIARMVEEFSSFARMPKPSVAPFDMRDLLQEAIFSQSVVSPDIDIMLETDLKTAPYLGDDRLLGQAFGNLLKNAAEAIEG
QPIEHDVSGHIRIILQQEVRGLEIIIEDNGPGFPAEVRNRLLEPYVTTREKGTGLGLAIVNRIIVDHGGSISLQNRPDGL
RGARVRVVLPENGALVMQSEDNSADEVGGTDRLPYPLSL

Sequences:

>Translated_759_residues
MSTTAANSQANKASWALFEGLFIIAALVAVFATFIAISGVVPDDPTAGATPWLLGLNFILLIVLAIIVTREYLQIRVGKE
DGSGKLARRFVLLFGFSALIPAMVVAVFMGTFITRGLDRWLGERVDHLMEQNAEIFRTYVENFQATFDSDMRLAALDVES
FARQVDQSLAIAPPTEDGDGAIYDYASTTFFDGLRSELASREFLTIAILGADGVDLVAEASVQEPILLLPPKSAYLEADE
GAVATTLYEGRGLATALIRISAPTDGYIYAVKVFDRNAARSLREAEAALEEYYAAKRSGGRLQIIFVIGYAQIAGLVLLL
AGRLGLEAAGRVTGPIGRLASAAHTVRDGDLSVRVPVSGPVDELHALGHSFNAMTEQLANQREALIRARNDEEDRRRFVE
TLLAELGAGVMRVGPDGMISLANRSAAEMLGLPGIDEGAPLSSVAPEFERYVRDTIERDAPVDATLDLSIGGETRNIRLK
TALGPEGGCVITFDDTTRLVNAQRQLAWRDVARRIAHEIRNPLTPIMLSTERLKRRYGPKIDDPDGVFDRCIETILRKVD
DIARMVEEFSSFARMPKPSVAPFDMRDLLQEAIFSQSVVSPDIDIMLETDLKTAPYLGDDRLLGQAFGNLLKNAAEAIEG
QPIEHDVSGHIRIILQQEVRGLEIIIEDNGPGFPAEVRNRLLEPYVTTREKGTGLGLAIVNRIIVDHGGSISLQNRPDGL
RGARVRVVLPENGALVMQSEDNSADEVGGTDRLPYPLSL
>Mature_758_residues
STTAANSQANKASWALFEGLFIIAALVAVFATFIAISGVVPDDPTAGATPWLLGLNFILLIVLAIIVTREYLQIRVGKED
GSGKLARRFVLLFGFSALIPAMVVAVFMGTFITRGLDRWLGERVDHLMEQNAEIFRTYVENFQATFDSDMRLAALDVESF
ARQVDQSLAIAPPTEDGDGAIYDYASTTFFDGLRSELASREFLTIAILGADGVDLVAEASVQEPILLLPPKSAYLEADEG
AVATTLYEGRGLATALIRISAPTDGYIYAVKVFDRNAARSLREAEAALEEYYAAKRSGGRLQIIFVIGYAQIAGLVLLLA
GRLGLEAAGRVTGPIGRLASAAHTVRDGDLSVRVPVSGPVDELHALGHSFNAMTEQLANQREALIRARNDEEDRRRFVET
LLAELGAGVMRVGPDGMISLANRSAAEMLGLPGIDEGAPLSSVAPEFERYVRDTIERDAPVDATLDLSIGGETRNIRLKT
ALGPEGGCVITFDDTTRLVNAQRQLAWRDVARRIAHEIRNPLTPIMLSTERLKRRYGPKIDDPDGVFDRCIETILRKVDD
IARMVEEFSSFARMPKPSVAPFDMRDLLQEAIFSQSVVSPDIDIMLETDLKTAPYLGDDRLLGQAFGNLLKNAAEAIEGQ
PIEHDVSGHIRIILQQEVRGLEIIIEDNGPGFPAEVRNRLLEPYVTTREKGTGLGLAIVNRIIVDHGGSISLQNRPDGLR
GARVRVVLPENGALVMQSEDNSADEVGGTDRLPYPLSL

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=420, Percent_Identity=27.6190476190476, Blast_Score=110, Evalue=5e-25,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=27.7272727272727, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790300, Length=268, Percent_Identity=26.4925373134328, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=226, Percent_Identity=29.2035398230088, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=221, Percent_Identity=28.0542986425339, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786600, Length=368, Percent_Identity=23.9130434782609, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=26.431718061674, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82603; Mature: 82472

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTAANSQANKASWALFEGLFIIAALVAVFATFIAISGVVPDDPTAGATPWLLGLNFIL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LIVLAIIVTREYLQIRVGKEDGSGKLARRFVLLFGFSALIPAMVVAVFMGTFITRGLDRW
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGERVDHLMEQNAEIFRTYVENFQATFDSDMRLAALDVESFARQVDQSLAIAPPTEDGDG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCC
AIYDYASTTFFDGLRSELASREFLTIAILGADGVDLVAEASVQEPILLLPPKSAYLEADE
CEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCCCCEEEECCCHHCEECCC
GAVATTLYEGRGLATALIRISAPTDGYIYAVKVFDRNAARSLREAEAALEEYYAAKRSGG
CCEEEEEECCCCCEEEEEEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
RLQIIFVIGYAQIAGLVLLLAGRLGLEAAGRVTGPIGRLASAAHTVRDGDLSVRVPVSGP
EEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEECCCEEEEEECCCC
VDELHALGHSFNAMTEQLANQREALIRARNDEEDRRRFVETLLAELGAGVMRVGPDGMIS
HHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEE
LANRSAAEMLGLPGIDEGAPLSSVAPEFERYVRDTIERDAPVDATLDLSIGGETRNIRLK
CCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEE
TALGPEGGCVITFDDTTRLVNAQRQLAWRDVARRIAHEIRNPLTPIMLSTERLKRRYGPK
EECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECHHHHHHHCCCC
IDDPDGVFDRCIETILRKVDDIARMVEEFSSFARMPKPSVAPFDMRDLLQEAIFSQSVVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
PDIDIMLETDLKTAPYLGDDRLLGQAFGNLLKNAAEAIEGQPIEHDVSGHIRIILQQEVR
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
GLEIIIEDNGPGFPAEVRNRLLEPYVTTREKGTGLGLAIVNRIIVDHGGSISLQNRPDGL
CEEEEEECCCCCCCHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
RGARVRVVLPENGALVMQSEDNSADEVGGTDRLPYPLSL
CCCEEEEEECCCCEEEEECCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STTAANSQANKASWALFEGLFIIAALVAVFATFIAISGVVPDDPTAGATPWLLGLNFIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LIVLAIIVTREYLQIRVGKEDGSGKLARRFVLLFGFSALIPAMVVAVFMGTFITRGLDRW
HHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGERVDHLMEQNAEIFRTYVENFQATFDSDMRLAALDVESFARQVDQSLAIAPPTEDGDG
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCCCC
AIYDYASTTFFDGLRSELASREFLTIAILGADGVDLVAEASVQEPILLLPPKSAYLEADE
CEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCCCCEEEECCCHHCEECCC
GAVATTLYEGRGLATALIRISAPTDGYIYAVKVFDRNAARSLREAEAALEEYYAAKRSGG
CCEEEEEECCCCCEEEEEEEECCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
RLQIIFVIGYAQIAGLVLLLAGRLGLEAAGRVTGPIGRLASAAHTVRDGDLSVRVPVSGP
EEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEECCCEEEEEECCCC
VDELHALGHSFNAMTEQLANQREALIRARNDEEDRRRFVETLLAELGAGVMRVGPDGMIS
HHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEE
LANRSAAEMLGLPGIDEGAPLSSVAPEFERYVRDTIERDAPVDATLDLSIGGETRNIRLK
CCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEE
TALGPEGGCVITFDDTTRLVNAQRQLAWRDVARRIAHEIRNPLTPIMLSTERLKRRYGPK
EECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECHHHHHHHCCCC
IDDPDGVFDRCIETILRKVDDIARMVEEFSSFARMPKPSVAPFDMRDLLQEAIFSQSVVS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
PDIDIMLETDLKTAPYLGDDRLLGQAFGNLLKNAAEAIEGQPIEHDVSGHIRIILQQEVR
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCC
GLEIIIEDNGPGFPAEVRNRLLEPYVTTREKGTGLGLAIVNRIIVDHGGSISLQNRPDGL
CEEEEEECCCCCCCHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCC
RGARVRVVLPENGALVMQSEDNSADEVGGTDRLPYPLSL
CCCEEEEEECCCCEEEEECCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]