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The map label for this gene is gmhB [H]

Identifier: 114800219

GI number: 114800219

Start: 481670

End: 482200

Strand: Reverse

Name: gmhB [H]

Synonym: HNE_0490

Alternate gene names: 114800219

Gene position: 482200-481670 (Counterclockwise)

Preceding gene: 114797216

Following gene: 114800118

Centisome position: 13.01

GC content: 60.83

Gene sequence:

>531_bases
ATGAACAAACATCGCCCCGCCCTCTTTCTGGACAGAGACGGCGTCATCAATATCGACCGGGGCTATGTCAGCCGCATCGA
AGACTTCGAGTTCATCGAAGGCGCGGCTGAAACCATTGCCGCCTTCAACCAGCGTGGCTGGTATGTCTTCATCGTCACCA
ACCAGTCCGGTATCGCCCGCAACTACTATACCGAAGACGACATGCACGCCCTGCATGACTGGATGCAGGCGCGCCTCGCC
GAAAAAGGCGCGCATATCGACCGGATCTATTTCTGCCCCTTCCACGAAGACGGCGAAAACCTCCGCTACCGGAAGGACAG
CTTCGACCGCAAACCCAAGCCCGGCATGCTCCTGCGCGCGATGGCAGACTTCCCGGTGAAGCGCGAAGCCAGCTTCCTCA
TCGGCGACAAGGAGGCCGACATCGAAGCAGCCAAAGCCGCCAGCGTGGCCGGCTTCCTCTTCACCGGCGGGAACCTCGCC
ACCTTCGCCGAATGGACGCTGGCGAGCTTCGAGGATGGCAACAGGGGCTGA

Upstream 100 bases:

>100_bases
TGTCACAGGGGCAAGTGTTTCGCAGAAGCCCTTGACTGTCGATCCTTTTCGCGCCTCTGGAGAGGATTGCATCCTCCCGC
GAAGCTGCCACATAGAGCCC

Downstream 100 bases:

>100_bases
GCTTCCGCTTCGCGCTCGCCTCCCCCTGCAATCTATGCTAGCCAACGTGGATGCACTACCATTGCGCAGATAGCGCCCTC
TCATGAAGGGATACGGCCCC

Product: D,D-heptose 1,7-bisphosphate phosphatase family protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MNKHRPALFLDRDGVINIDRGYVSRIEDFEFIEGAAETIAAFNQRGWYVFIVTNQSGIARNYYTEDDMHALHDWMQARLA
EKGAHIDRIYFCPFHEDGENLRYRKDSFDRKPKPGMLLRAMADFPVKREASFLIGDKEADIEAAKAASVAGFLFTGGNLA
TFAEWTLASFEDGNRG

Sequences:

>Translated_176_residues
MNKHRPALFLDRDGVINIDRGYVSRIEDFEFIEGAAETIAAFNQRGWYVFIVTNQSGIARNYYTEDDMHALHDWMQARLA
EKGAHIDRIYFCPFHEDGENLRYRKDSFDRKPKPGMLLRAMADFPVKREASFLIGDKEADIEAAKAASVAGFLFTGGNLA
TFAEWTLASFEDGNRG
>Mature_176_residues
MNKHRPALFLDRDGVINIDRGYVSRIEDFEFIEGAAETIAAFNQRGWYVFIVTNQSGIARNYYTEDDMHALHDWMQARLA
EKGAHIDRIYFCPFHEDGENLRYRKDSFDRKPKPGMLLRAMADFPVKREASFLIGDKEADIEAAKAASVAGFLFTGGNLA
TFAEWTLASFEDGNRG

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=178, Percent_Identity=42.1348314606742, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082027, Length=151, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20037; Mature: 20037

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHRPALFLDRDGVINIDRGYVSRIEDFEFIEGAAETIAAFNQRGWYVFIVTNQSGIAR
CCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
NYYTEDDMHALHDWMQARLAEKGAHIDRIYFCPFHEDGENLRYRKDSFDRKPKPGMLLRA
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHH
MADFPVKREASFLIGDKEADIEAAKAASVAGFLFTGGNLATFAEWTLASFEDGNRG
HHCCCCCCCCEEEECCCCCCHHHHHHHHHEEEEEECCCEEEHHHHHEECCCCCCCC
>Mature Secondary Structure
MNKHRPALFLDRDGVINIDRGYVSRIEDFEFIEGAAETIAAFNQRGWYVFIVTNQSGIAR
CCCCCCEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
NYYTEDDMHALHDWMQARLAEKGAHIDRIYFCPFHEDGENLRYRKDSFDRKPKPGMLLRA
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHH
MADFPVKREASFLIGDKEADIEAAKAASVAGFLFTGGNLATFAEWTLASFEDGNRG
HHCCCCCCCCEEEECCCCCCHHHHHHHHHEEEEEECCCEEEHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]