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The map label for this gene is yclF [H]

Identifier: 114800217

GI number: 114800217

Start: 1406411

End: 1408435

Strand: Direct

Name: yclF [H]

Synonym: HNE_1376

Alternate gene names: 114800217

Gene position: 1406411-1408435 (Clockwise)

Preceding gene: 114798387

Following gene: 114799018

Centisome position: 37.96

GC content: 61.58

Gene sequence:

>2025_bases
ATGACAGCACCGCCTTCGGAAAAGAGCTTTCTGGGCCATCCGCGAGGCCTGGTAATCTGCTTCCTCACCGAGATGTGGGA
GCGGTTTTCGTATTACGGGATGCGCGGCCTGCTGCTGCTTTACCTGACGCAGCACTTCCTGTTTTCGGATGAGCGATCGA
ATGTGATCTATGGCGCCTACATTGCGCTGGTTTACATCATGTCGATTGTCGGCGGCGTGCTCTCTGACAAATATCTGGGC
CAGCGCAAGGCGGTGACCTTTGGCGCGATCCTGCTGGTGCTCGGCCATTTCGGGATGGCGTTTGAGGGCAGCGGATCGCG
CGAAACGATCATCACCGAAAGCGGCAATTACCTCGTCGAGGCCGAAGGGCGCGACAATCGCCGGCAGCTGTTCATCGACT
ATGAAGGCGAGCCGCGCCGGCTGATTTTTGACTCCACACAATTTGCGACGCTGGGCGATGACCGCATCCTGCCGATCAAT
GAGGCAGGCGTGGGTGACTATGAAATCCAGCGCGAAACGCGCGGGTTTATTCAGAATGTCTGCGCGCTTGTCGGGCTTGG
CTGCGCCGGGCCGGAGCCGACCACGACGCTGATCCTCAATGGCGAAGCGTTTCCGGTTGAGGAAACCCGTGACGGCATGA
TGGTCGACCGTAACGGCCAGATGCTGCCGCTTGTGGAAAGCAGCGAGACCGACATTCTCGTGCTGGGTGACGCAACGACG
GAAGGCGCGCCTGACATCTCCGCGCCGGTGGCGACCTTTGCCGATGGTGCCTACTCGACGCAGGTTGAGCAGGAGATGCT
GTATGTGAACATCCTCTACATCTCGCTGGCGTTGATCATTGCAGGCGTCGGCTTCCTGAAGCCGAACATTTCGACCATCG
TGGGTGATCTGTACCCTGAAGGGGACCCGCGGCGGGATGGCGGGTTCACGCTGTTCTATATGGGGATCAATCTCGGCTCG
TTCCTGGCGACGTGGACGTGCGGTATTCTGGGCATTGTTTATGGCTGGGCCTGGGGCTTTGGCGCGGCGGGCGTCGGCAT
GCTGCTCGGCCTGGTCGTGTTCCACTACGGCCAGCATTGGCTGGACGGGAAGGCGGAGCCGCCATCGCGCGAGAAGCTGC
GCGAGAAGGTGTTCGGGCTGATTACGGTCGAGACCGCGTGCTACGCTTCGGCGCTGGGCATCATTGCGGTGTCGATTGCG
CTGCTGATGAATGCCGGGATTGTCGACACGCTGGCGATGATCACCGGCATCGGGATGTTCGTCGTGCTGATCGGATATTC
GTTCCTGCGCCTCAAGGGCGCGGCGCGGACGCGGATGTGGGCGGCGGTATATTTTGCCATCGCGCAGATCCCGTTCTGGT
CCCTGTTCGAGCAGGCCGGTTCCTCGCTGACACTGGTGACGAGCCGCCTGGTGAACACCAACATGTTCGGCTGGAACGTG
CCGACGCCGGTGTTCCAGTCGCTGAATGCGGGCTTCATCTTCCTGTTTGCGCCGCTCGTGGCGTGGCTGTGGCTGGCGCT
GGCCAGGCGGGGCTGGGAGCCTTCAACGCCCGTGAAGTTTGCCATCGGCGTGTTCGGGGCGGGGCTTGGCTATCTTGTGC
TGGTGGGCGGCATGTCGAGCGTTGGCGCCGCGGCGCTGACGCCGGTGTTCTTCATCTTCGCCATCTACTGGATCCACACG
ATGGCGGAGCTGATGCTCTCGCCGGTTGGCCTGTCGGCGATGACGAAGCTGGCACCGGCCTCGCTGGTCGGCCTCTTCAT
GGCAGCCTGGTTTGTCTATTCGGGCCTGGGGAATGCGATGTCCGGCGTTATTGCGGCCGCTGCCGGTGCAGAAACCGTTG
GTGGGCAGATTGTCGATGTGGCCGGGGCCAAGGCGAACTACATCCAGGTGTTCTCGTCCATCGGCTATATCGGCATGATC
ATCGGCTTCCTGATGCTGCTGGTGGCGCCGATCGTGAAACGCTGGATGGCCGAAGCGCAGATCGAGGAGCGCCCGCTGAG
CACTGACTCCGTTGGGCATAACTGA

Upstream 100 bases:

>100_bases
GCCGCTGGCCTAACGGCAGAAACTGCCTTGAGCGCCCGCCCTCCCCGTGGTCAAACCTTTGACATAATTCAGCGCGCTGG
GGAGCATTTACGTGACAGAC

Downstream 100 bases:

>100_bases
AACCCGGTAAAAAGACGGCCTCAAATGAAACGGGGCGCTCCTGTGGGGCGCCCCGCTTTATTTCGTCCGGGAGGGGACAA
AGTTATTCCTCGCCTTCTCC

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MTAPPSEKSFLGHPRGLVICFLTEMWERFSYYGMRGLLLLYLTQHFLFSDERSNVIYGAYIALVYIMSIVGGVLSDKYLG
QRKAVTFGAILLVLGHFGMAFEGSGSRETIITESGNYLVEAEGRDNRRQLFIDYEGEPRRLIFDSTQFATLGDDRILPIN
EAGVGDYEIQRETRGFIQNVCALVGLGCAGPEPTTTLILNGEAFPVEETRDGMMVDRNGQMLPLVESSETDILVLGDATT
EGAPDISAPVATFADGAYSTQVEQEMLYVNILYISLALIIAGVGFLKPNISTIVGDLYPEGDPRRDGGFTLFYMGINLGS
FLATWTCGILGIVYGWAWGFGAAGVGMLLGLVVFHYGQHWLDGKAEPPSREKLREKVFGLITVETACYASALGIIAVSIA
LLMNAGIVDTLAMITGIGMFVVLIGYSFLRLKGAARTRMWAAVYFAIAQIPFWSLFEQAGSSLTLVTSRLVNTNMFGWNV
PTPVFQSLNAGFIFLFAPLVAWLWLALARRGWEPSTPVKFAIGVFGAGLGYLVLVGGMSSVGAAALTPVFFIFAIYWIHT
MAELMLSPVGLSAMTKLAPASLVGLFMAAWFVYSGLGNAMSGVIAAAAGAETVGGQIVDVAGAKANYIQVFSSIGYIGMI
IGFLMLLVAPIVKRWMAEAQIEERPLSTDSVGHN

Sequences:

>Translated_674_residues
MTAPPSEKSFLGHPRGLVICFLTEMWERFSYYGMRGLLLLYLTQHFLFSDERSNVIYGAYIALVYIMSIVGGVLSDKYLG
QRKAVTFGAILLVLGHFGMAFEGSGSRETIITESGNYLVEAEGRDNRRQLFIDYEGEPRRLIFDSTQFATLGDDRILPIN
EAGVGDYEIQRETRGFIQNVCALVGLGCAGPEPTTTLILNGEAFPVEETRDGMMVDRNGQMLPLVESSETDILVLGDATT
EGAPDISAPVATFADGAYSTQVEQEMLYVNILYISLALIIAGVGFLKPNISTIVGDLYPEGDPRRDGGFTLFYMGINLGS
FLATWTCGILGIVYGWAWGFGAAGVGMLLGLVVFHYGQHWLDGKAEPPSREKLREKVFGLITVETACYASALGIIAVSIA
LLMNAGIVDTLAMITGIGMFVVLIGYSFLRLKGAARTRMWAAVYFAIAQIPFWSLFEQAGSSLTLVTSRLVNTNMFGWNV
PTPVFQSLNAGFIFLFAPLVAWLWLALARRGWEPSTPVKFAIGVFGAGLGYLVLVGGMSSVGAAALTPVFFIFAIYWIHT
MAELMLSPVGLSAMTKLAPASLVGLFMAAWFVYSGLGNAMSGVIAAAAGAETVGGQIVDVAGAKANYIQVFSSIGYIGMI
IGFLMLLVAPIVKRWMAEAQIEERPLSTDSVGHN
>Mature_673_residues
TAPPSEKSFLGHPRGLVICFLTEMWERFSYYGMRGLLLLYLTQHFLFSDERSNVIYGAYIALVYIMSIVGGVLSDKYLGQ
RKAVTFGAILLVLGHFGMAFEGSGSRETIITESGNYLVEAEGRDNRRQLFIDYEGEPRRLIFDSTQFATLGDDRILPINE
AGVGDYEIQRETRGFIQNVCALVGLGCAGPEPTTTLILNGEAFPVEETRDGMMVDRNGQMLPLVESSETDILVLGDATTE
GAPDISAPVATFADGAYSTQVEQEMLYVNILYISLALIIAGVGFLKPNISTIVGDLYPEGDPRRDGGFTLFYMGINLGSF
LATWTCGILGIVYGWAWGFGAAGVGMLLGLVVFHYGQHWLDGKAEPPSREKLREKVFGLITVETACYASALGIIAVSIAL
LMNAGIVDTLAMITGIGMFVVLIGYSFLRLKGAARTRMWAAVYFAIAQIPFWSLFEQAGSSLTLVTSRLVNTNMFGWNVP
TPVFQSLNAGFIFLFAPLVAWLWLALARRGWEPSTPVKFAIGVFGAGLGYLVLVGGMSSVGAAALTPVFFIFAIYWIHTM
AELMLSPVGLSAMTKLAPASLVGLFMAAWFVYSGLGNAMSGVIAAAAGAETVGGQIVDVAGAKANYIQVFSSIGYIGMII
GFLMLLVAPIVKRWMAEAQIEERPLSTDSVGHN

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=91, Percent_Identity=36.2637362637363, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787922, Length=384, Percent_Identity=30.2083333333333, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1789911, Length=399, Percent_Identity=26.8170426065163, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786927, Length=413, Percent_Identity=30.0242130750605, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790572, Length=372, Percent_Identity=30.6451612903226, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28571102, Length=99, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571100, Length=99, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639581, Length=99, Percent_Identity=32.3232323232323, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28571098, Length=99, Percent_Identity=32.3232323232323, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24639585, Length=91, Percent_Identity=31.8681318681319, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639583, Length=91, Percent_Identity=31.8681318681319, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 72854; Mature: 72723

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPPSEKSFLGHPRGLVICFLTEMWERFSYYGMRGLLLLYLTQHFLFSDERSNVIYGAY
CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHH
IALVYIMSIVGGVLSDKYLGQRKAVTFGAILLVLGHFGMAFEGSGSRETIITESGNYLVE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCEEEE
AEGRDNRRQLFIDYEGEPRRLIFDSTQFATLGDDRILPINEAGVGDYEIQRETRGFIQNV
ECCCCCCEEEEEEECCCCCEEEECCCCEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHH
CALVGLGCAGPEPTTTLILNGEAFPVEETRDGMMVDRNGQMLPLVESSETDILVLGDATT
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECCCCCEEEEECCCC
EGAPDISAPVATFADGAYSTQVEQEMLYVNILYISLALIIAGVGFLKPNISTIVGDLYPE
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
GDPRRDGGFTLFYMGINLGSFLATWTCGILGIVYGWAWGFGAAGVGMLLGLVVFHYGQHW
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LDGKAEPPSREKLREKVFGLITVETACYASALGIIAVSIALLMNAGIVDTLAMITGIGMF
CCCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLIGYSFLRLKGAARTRMWAAVYFAIAQIPFWSLFEQAGSSLTLVTSRLVNTNMFGWNV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEHHHHHHHCCCCCCCC
PTPVFQSLNAGFIFLFAPLVAWLWLALARRGWEPSTPVKFAIGVFGAGLGYLVLVGGMSS
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHCCCCHH
VGAAALTPVFFIFAIYWIHTMAELMLSPVGLSAMTKLAPASLVGLFMAAWFVYSGLGNAM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGVIAAAAGAETVGGQIVDVAGAKANYIQVFSSIGYIGMIIGFLMLLVAPIVKRWMAEAQ
HHHHHHHCCCHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IEERPLSTDSVGHN
HHHCCCCCCCCCCC
>Mature Secondary Structure 
TAPPSEKSFLGHPRGLVICFLTEMWERFSYYGMRGLLLLYLTQHFLFSDERSNVIYGAY
CCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHH
IALVYIMSIVGGVLSDKYLGQRKAVTFGAILLVLGHFGMAFEGSGSRETIITESGNYLVE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCEEEE
AEGRDNRRQLFIDYEGEPRRLIFDSTQFATLGDDRILPINEAGVGDYEIQRETRGFIQNV
ECCCCCCEEEEEEECCCCCEEEECCCCEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHH
CALVGLGCAGPEPTTTLILNGEAFPVEETRDGMMVDRNGQMLPLVESSETDILVLGDATT
HHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCEEEEEECCCCCEEEEECCCC
EGAPDISAPVATFADGAYSTQVEQEMLYVNILYISLALIIAGVGFLKPNISTIVGDLYPE
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
GDPRRDGGFTLFYMGINLGSFLATWTCGILGIVYGWAWGFGAAGVGMLLGLVVFHYGQHW
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LDGKAEPPSREKLREKVFGLITVETACYASALGIIAVSIALLMNAGIVDTLAMITGIGMF
CCCCCCCCHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLIGYSFLRLKGAARTRMWAAVYFAIAQIPFWSLFEQAGSSLTLVTSRLVNTNMFGWNV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEHHHHHHHCCCCCCCC
PTPVFQSLNAGFIFLFAPLVAWLWLALARRGWEPSTPVKFAIGVFGAGLGYLVLVGGMSS
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHCCCCHH
VGAAALTPVFFIFAIYWIHTMAELMLSPVGLSAMTKLAPASLVGLFMAAWFVYSGLGNAM
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGVIAAAAGAETVGGQIVDVAGAKANYIQVFSSIGYIGMIIGFLMLLVAPIVKRWMAEAQ
HHHHHHHCCCHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IEERPLSTDSVGHN
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]