Click here to switch to the map view.

The map label for this gene is panD

Identifier: 114799018

GI number: 114799018

Start: 1410647

End: 1411003

Strand: Direct

Name: panD

Synonym: HNE_1379

Alternate gene names: 114799018

Gene position: 1410647-1411003 (Clockwise)

Preceding gene: 114800217

Following gene: 114799712

Centisome position: 38.07

GC content: 62.75

Gene sequence:

>357_bases
TTGATCCTCAGCATGCTCAAAGCCAAGCTTCACGGCGCAACTGTCACCCAGTGTGACCTGCATTATGAAGGCTCTGTGTC
CATCGACCAGGACCTGCTCGATGCGTCCGGTATCCTGCCGCATGAGAAGGTGGATATCTGGAACGTGACCAATGGCGCGC
GCATCCAGACCTATGCTCTGGAAGCCCCCCGTGGCTCCCGCACCATTGGCGTCAATGGCGCGGCGGCCCGCCACTTCGCC
GTGGGCGACACGGTGATCATCGCGGCGTTCTGCGGCGTGGAAGCGGAAAAAGCCCGCCAGCATGCGCCGACCGTGGTGCT
GCTCGGCGAAGGCAACGAGATCAAGCGCGCCTCCTGA

Upstream 100 bases:

>100_bases
GCCCGCATATTGCAATGCAATAAGCCCTTGCTCCGCTGTGGGGCGACCCCATATTCTCGTCGTGAGCAAAAGTGCTCACG
GTGTTCTGGAGACCCGGTCC

Downstream 100 bases:

>100_bases
TTGCGCTGCCATTCCGGCTGATCTGTTTCGTCAGACTTCAAACGCGTCCAGGATCGGGCAGGAGCCGGACTTACCCGCAG
CGCATTCTGTTGCCAGCCTC

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MILSMLKAKLHGATVTQCDLHYEGSVSIDQDLLDASGILPHEKVDIWNVTNGARIQTYALEAPRGSRTIGVNGAAARHFA
VGDTVIIAAFCGVEAEKARQHAPTVVLLGEGNEIKRAS

Sequences:

>Translated_118_residues
MILSMLKAKLHGATVTQCDLHYEGSVSIDQDLLDASGILPHEKVDIWNVTNGARIQTYALEAPRGSRTIGVNGAAARHFA
VGDTVIIAAFCGVEAEKARQHAPTVVLLGEGNEIKRAS
>Mature_118_residues
MILSMLKAKLHGATVTQCDLHYEGSVSIDQDLLDASGILPHEKVDIWNVTNGARIQTYALEAPRGSRTIGVNGAAARHFA
VGDTVIIAAFCGVEAEKARQHAPTVVLLGEGNEIKRAS

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=118, Percent_Identity=57.6271186440678, Blast_Score=136, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_HYPNA (Q0C2E7)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760096.1
- ProteinModelPortal:   Q0C2E7
- SMR:   Q0C2E7
- STRING:   Q0C2E7
- GeneID:   4287535
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1379
- NMPDR:   fig|228405.5.peg.1340
- TIGR:   HNE_1379
- eggNOG:   COG0853
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- PhylomeDB:   Q0C2E7
- ProtClustDB:   PRK05449
- BioCyc:   HNEP81032:HNE_1379-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 12548; Mature: 12548

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSMLKAKLHGATVTQCDLHYEGSVSIDQDLLDASGILPHEKVDIWNVTNGARIQTYAL
CCHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEEEEEE
EAPRGSRTIGVNGAAARHFAVGDTVIIAAFCGVEAEKARQHAPTVVLLGEGNEIKRAS
ECCCCCEEEECCCCCCEEEECCCEEEEEEECCCCHHHHHCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MILSMLKAKLHGATVTQCDLHYEGSVSIDQDLLDASGILPHEKVDIWNVTNGARIQTYAL
CCHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEEEEEE
EAPRGSRTIGVNGAAARHFAVGDTVIIAAFCGVEAEKARQHAPTVVLLGEGNEIKRAS
ECCCCCEEEECCCCCCEEEECCCEEEEEEECCCCHHHHHCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA