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The map label for this gene is ccmB [H]

Identifier: 114800180

GI number: 114800180

Start: 3652130

End: 3652795

Strand: Direct

Name: ccmB [H]

Synonym: HNE_3516

Alternate gene names: 114800180

Gene position: 3652130-3652795 (Clockwise)

Preceding gene: 114800037

Following gene: 114800532

Centisome position: 98.57

GC content: 68.77

Gene sequence:

>666_bases
TTGAACGCGGCGCCCATCTGGGCAGCGTTCCGGCAGGCGTTTGCCGAAGCATGGGCGGGCGGCGCAGGCGCGCTGCTGCC
GCTTGGCTTTCTGGGCGGGGCGGCGGTGCTGGTGCCCCTGGGTATCGGAAGCGATACCGAGACCCTCAAGGCGGTAGGGC
CAGGCATCATCTGGGTATCGCTTGCGCTATCCAGCCTGGTGACGCTGGAGCGGATCTTTCAGGCGGATGTGGAGGACGGC
ACGCTGGACCTCTGGCTGCAGACCGGCGCGCCGATGGCAGCGGTTGCGGCGGCCAAGACGCTGGCGCACTGGCTGGCGGC
GGGATTGCCCCTCGCGCTGGCCTCTCCCCTGCTGGCGCTGATGTTCCAGGCGCAGGCGAGCCTGGACCTGATCGCACATC
TTGGGCTCTACGCCCTTGGCAGCCTGGCGTTTTTCTTCTGGGGCGGGGTGGGCGCCGCCCTATCAGCCACCGTGCGCCGG
GGCGGGCTGCTGATCTCGATCATCGCGCTTCCCCTCTATGTGCCCACCGCCATTTTCGGCAGCCTGGCAATGACCGGGGG
CATCGGATCTGACGGGGCGCCGATGCTGCTGGCCGCTTCCACCCTCTTTGCCTGCGCTGTTGCGCCCTATGCCATGGCCG
CTGCCTTGCGCTTGGCGGCGGACTGA

Upstream 100 bases:

>100_bases
TGCTCGATCAGGTCATTTCAGGACATTTGAGGACAGGTGGGGCCATTATCGCGTCGATGCACGACGCGGCCGGCTTCCCG
GTGACTGCCGAGGTGACGCT

Downstream 100 bases:

>100_bases
GGGGAGGCTATCTCGATACCATCATGTGGTCTGCCTTTGCCAATCCGCACAAGTTTCTGAAATTCTCCGCTGTTGCGGCG
CCCCTTTTCTATGGAGCGGG

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNAAPIWAAFRQAFAEAWAGGAGALLPLGFLGGAAVLVPLGIGSDTETLKAVGPGIIWVSLALSSLVTLERIFQADVEDG
TLDLWLQTGAPMAAVAAAKTLAHWLAAGLPLALASPLLALMFQAQASLDLIAHLGLYALGSLAFFFWGGVGAALSATVRR
GGLLISIIALPLYVPTAIFGSLAMTGGIGSDGAPMLLAASTLFACAVAPYAMAAALRLAAD

Sequences:

>Translated_221_residues
MNAAPIWAAFRQAFAEAWAGGAGALLPLGFLGGAAVLVPLGIGSDTETLKAVGPGIIWVSLALSSLVTLERIFQADVEDG
TLDLWLQTGAPMAAVAAAKTLAHWLAAGLPLALASPLLALMFQAQASLDLIAHLGLYALGSLAFFFWGGVGAALSATVRR
GGLLISIIALPLYVPTAIFGSLAMTGGIGSDGAPMLLAASTLFACAVAPYAMAAALRLAAD
>Mature_221_residues
MNAAPIWAAFRQAFAEAWAGGAGALLPLGFLGGAAVLVPLGIGSDTETLKAVGPGIIWVSLALSSLVTLERIFQADVEDG
TLDLWLQTGAPMAAVAAAKTLAHWLAAGLPLALASPLLALMFQAQASLDLIAHLGLYALGSLAFFFWGGVGAALSATVRR
GGLLISIIALPLYVPTAIFGSLAMTGGIGSDGAPMLLAASTLFACAVAPYAMAAALRLAAD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=217, Percent_Identity=37.3271889400922, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22228; Mature: 22228

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00578 RIBOSOMAL_S6E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAPIWAAFRQAFAEAWAGGAGALLPLGFLGGAAVLVPLGIGSDTETLKAVGPGIIWVS
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEECCCCCHHHHHHHCCHHHHHH
LALSSLVTLERIFQADVEDGTLDLWLQTGAPMAAVAAAKTLAHWLAAGLPLALASPLLAL
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MFQAQASLDLIAHLGLYALGSLAFFFWGGVGAALSATVRRGGLLISIIALPLYVPTAIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SLAMTGGIGSDGAPMLLAASTLFACAVAPYAMAAALRLAAD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAAPIWAAFRQAFAEAWAGGAGALLPLGFLGGAAVLVPLGIGSDTETLKAVGPGIIWVS
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEECCCCCHHHHHHHCCHHHHHH
LALSSLVTLERIFQADVEDGTLDLWLQTGAPMAAVAAAKTLAHWLAAGLPLALASPLLAL
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MFQAQASLDLIAHLGLYALGSLAFFFWGGVGAALSATVRRGGLLISIIALPLYVPTAIFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
SLAMTGGIGSDGAPMLLAASTLFACAVAPYAMAAALRLAAD
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]