Click here to switch to the map view.

The map label for this gene is 114800089

Identifier: 114800089

GI number: 114800089

Start: 1061404

End: 1061886

Strand: Direct

Name: 114800089

Synonym: HNE_1052

Alternate gene names: NA

Gene position: 1061404-1061886 (Clockwise)

Preceding gene: 114800284

Following gene: 114799116

Centisome position: 28.65

GC content: 62.73

Gene sequence:

>483_bases
ATGGCGATCAAAGTGGGCGACAAGCTGCCGGAAGCGACTTTTATGGAAATGACCGTGGATGGGCCAAAGCCCGTCACCAC
CGCGCAGGTGTTCGGCGGCAAGACGGTCGCGCTGTTCGCCGTGCCGGGCGCCTATACGCCGACCTGTTCGGCGCGCCACC
TGCCGGGCTATGTCGACAAGGCGGGCGATTTCAAAGCCAAGGGCGTGGACGAGATCGTCTGCACCTCGGTCAATGACGTG
TTCGTCATGGGCGCCTGGGGCAAATCCTCCAAAGCCGAGGAAGCCGTGCGGATGCTGGCAGATGGCAATGGCGCGTTTGC
CCAGTCGCTTGGCCTGGAACTCGACGCATCGGGCTTTGGCATGGGCAAGCGCTCGCAGCGCTATTCCATGCTGGTGAAGG
ACGGCGTTGTGGCCGAACTCAACGTTGAGCAGGGCGGCGAATTCAAGGTGTCGGCCGCCGACTACCTTCTCGGCCAACTC
TGA

Upstream 100 bases:

>100_bases
ACGCTCGCGCCCGCCAGTCCGGCATCCGTCTTCGGGGAAAGCATTGCGGGCGAGGCAAGAGCGGCCTATCTCCGCAGGAG
CAAGCAAGGAGAAAACTGCC

Downstream 100 bases:

>100_bases
GCCGATAGAAGGGGGCGTTAAGCGCCCTTTACCGAATACAGCCATGATCGGCCTGCTGCGGGGACGCGGTGGGCCGATTT
TCGTTGCAGATTTATTGAAA

Product: anti-oxidant AhpCTSA family protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MAIKVGDKLPEATFMEMTVDGPKPVTTAQVFGGKTVALFAVPGAYTPTCSARHLPGYVDKAGDFKAKGVDEIVCTSVNDV
FVMGAWGKSSKAEEAVRMLADGNGAFAQSLGLELDASGFGMGKRSQRYSMLVKDGVVAELNVEQGGEFKVSAADYLLGQL

Sequences:

>Translated_160_residues
MAIKVGDKLPEATFMEMTVDGPKPVTTAQVFGGKTVALFAVPGAYTPTCSARHLPGYVDKAGDFKAKGVDEIVCTSVNDV
FVMGAWGKSSKAEEAVRMLADGNGAFAQSLGLELDASGFGMGKRSQRYSMLVKDGVVAELNVEQGGEFKVSAADYLLGQL
>Mature_159_residues
AIKVGDKLPEATFMEMTVDGPKPVTTAQVFGGKTVALFAVPGAYTPTCSARHLPGYVDKAGDFKAKGVDEIVCTSVNDVF
VMGAWGKSSKAEEAVRMLADGNGAFAQSLGLELDASGFGMGKRSQRYSMLVKDGVVAELNVEQGGEFKVSAADYLLGQL

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=162, Percent_Identity=47.5308641975309, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6323138, Length=165, Percent_Identity=31.5151515151515, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI78706776, Length=146, Percent_Identity=51.3698630136986, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI78709078, Length=146, Percent_Identity=51.3698630136986, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR011906
- InterPro:   IPR014025
- InterPro:   IPR013740
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin; PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 16790; Mature: 16659

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVGDKLPEATFMEMTVDGPKPVTTAQVFGGKTVALFAVPGAYTPTCSARHLPGYVDK
CEEECCCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCC
AGDFKAKGVDEIVCTSVNDVFVMGAWGKSSKAEEAVRMLADGNGAFAQSLGLELDASGFG
CCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHCCCEECCCCCC
MGKRSQRYSMLVKDGVVAELNVEQGGEFKVSAADYLLGQL
CCCCCCCEEEEECCCEEEEEECCCCCCEEEEHHHHHHCCC
>Mature Secondary Structure 
AIKVGDKLPEATFMEMTVDGPKPVTTAQVFGGKTVALFAVPGAYTPTCSARHLPGYVDK
EEECCCCCCCCEEEEEEECCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCC
AGDFKAKGVDEIVCTSVNDVFVMGAWGKSSKAEEAVRMLADGNGAFAQSLGLELDASGFG
CCCCCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHCCCEECCCCCC
MGKRSQRYSMLVKDGVVAELNVEQGGEFKVSAADYLLGQL
CCCCCCCEEEEECCCEEEEEECCCCCCEEEEHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]