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The map label for this gene is qmcA [H]

Identifier: 114799116

GI number: 114799116

Start: 1062038

End: 1063003

Strand: Direct

Name: qmcA [H]

Synonym: HNE_1053

Alternate gene names: 114799116

Gene position: 1062038-1063003 (Clockwise)

Preceding gene: 114800089

Following gene: 114799456

Centisome position: 28.66

GC content: 63.66

Gene sequence:

>966_bases
ATGGACATCTTTCTGGCTGTATTTCTGCTGATCGGGGTGGTCGGCCTGATCGGCATCGTCTCGGCATTCAAATTCGTGCC
GCAGGGCCATAACTGGACGGTCGAGCGGTTTGGCCGGTACACGCGCACGCTGACCCCTGGGGTCTCGGTCATCACGCCCT
TCATCGACCGGATCGGGCGGAAGATGAACATGATGGAAACCGTCATGGAGGTGCCCCAGCAGGAGGTGATCACCAAGGAC
AACGCCATGGTGTCGTGCGATGCCATCGTGTTCATTCAGGTCATCGATGCCGTGCAGGCGGCGTATGAGGTGAACAATCT
CACCCATGCCATCTCCAACCTGTCGATGACCAATATCCGCACCGTGGTCGGTTCGATGGACCTCGACCAGGTGCTGTCGA
ACCGCGACGAGATCAATGCGCGCCTCCTGGGCACGATTGATGCGGCGACCCATCCGTGGGGGATCAAGGTGACGCGGATC
GAGATCAAGGATCTCACGCCCCCCGCCGACATCACCGAGGCGATGGCCCGGCAGATGAAGGCCGAGCGCCTGAAACGGGC
GGAAATTCTGACCGCCGAGGGCGAGAAACAGTCGGCCATCCTCAAGGCCGAGGGCCAGAAGCAGGCGCAGATCCTTCAGG
CCGAGGGCCGCAAGGAAGCGGCGTTCCGCGACGCTGAAGCGCGCGAGCGGGAAGCTGAGGCCGAGGCGAAGGCGACCGCG
ATGGTGTCTGAAGCCATCGCGCGGGGCGACGTCAACGCGATCAACTACTTCCTTGGCCAGGCCTATGTGGCCGCGTTCGA
GAAGCTGGCGACCTCGCCGCAGCAGCGCACGGTCATCATCCCGGCGGAGTTCTCGTCCATCCTCGGCACCATCGAGGGTA
TCCGTGGACTGACGGACGCCGCGAAGAACACGACCGCCCCGCCGCGCCCGCAAGGCGCTGTGCCGCCGACCCGGCGTGAG
GATTAG

Upstream 100 bases:

>100_bases
CCTGCTGCGGGGACGCGGTGGGCCGATTTTCGTTGCAGATTTATTGAAAAACGGCAAACTCGCCCCAACTCAAAAGTATC
GTCACTGTGGAGAGGGACCC

Downstream 100 bases:

>100_bases
ACCCGAGCGCGCGAAGGAGGCTCCGGATGGAAATTCTGCTGAGTGAACTGACTTGGTGGCACTGGGTTGCCCTGGGACTG
GTGCTGTTCGGGATCGAGAT

Product: HflC/HflK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MDIFLAVFLLIGVVGLIGIVSAFKFVPQGHNWTVERFGRYTRTLTPGVSVITPFIDRIGRKMNMMETVMEVPQQEVITKD
NAMVSCDAIVFIQVIDAVQAAYEVNNLTHAISNLSMTNIRTVVGSMDLDQVLSNRDEINARLLGTIDAATHPWGIKVTRI
EIKDLTPPADITEAMARQMKAERLKRAEILTAEGEKQSAILKAEGQKQAQILQAEGRKEAAFRDAEAREREAEAEAKATA
MVSEAIARGDVNAINYFLGQAYVAAFEKLATSPQQRTVIIPAEFSSILGTIEGIRGLTDAAKNTTAPPRPQGAVPPTRRE
D

Sequences:

>Translated_321_residues
MDIFLAVFLLIGVVGLIGIVSAFKFVPQGHNWTVERFGRYTRTLTPGVSVITPFIDRIGRKMNMMETVMEVPQQEVITKD
NAMVSCDAIVFIQVIDAVQAAYEVNNLTHAISNLSMTNIRTVVGSMDLDQVLSNRDEINARLLGTIDAATHPWGIKVTRI
EIKDLTPPADITEAMARQMKAERLKRAEILTAEGEKQSAILKAEGQKQAQILQAEGRKEAAFRDAEAREREAEAEAKATA
MVSEAIARGDVNAINYFLGQAYVAAFEKLATSPQQRTVIIPAEFSSILGTIEGIRGLTDAAKNTTAPPRPQGAVPPTRRE
D
>Mature_321_residues
MDIFLAVFLLIGVVGLIGIVSAFKFVPQGHNWTVERFGRYTRTLTPGVSVITPFIDRIGRKMNMMETVMEVPQQEVITKD
NAMVSCDAIVFIQVIDAVQAAYEVNNLTHAISNLSMTNIRTVVGSMDLDQVLSNRDEINARLLGTIDAATHPWGIKVTRI
EIKDLTPPADITEAMARQMKAERLKRAEILTAEGEKQSAILKAEGQKQAQILQAEGRKEAAFRDAEAREREAEAEAKATA
MVSEAIARGDVNAINYFLGQAYVAAFEKLATSPQQRTVIIPAEFSSILGTIEGIRGLTDAAKNTTAPPRPQGAVPPTRRE
D

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=292, Percent_Identity=34.9315068493151, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI21686995, Length=216, Percent_Identity=31.9444444444444, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI221316744, Length=215, Percent_Identity=32.093023255814, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38016911, Length=194, Percent_Identity=34.5360824742268, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI7657615, Length=184, Percent_Identity=26.6304347826087, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786697, Length=308, Percent_Identity=59.4155844155844, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI32564147, Length=273, Percent_Identity=37.7289377289377, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI193209764, Length=216, Percent_Identity=32.4074074074074, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17569493, Length=216, Percent_Identity=32.4074074074074, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25153583, Length=194, Percent_Identity=32.9896907216495, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71987612, Length=194, Percent_Identity=32.9896907216495, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71987621, Length=194, Percent_Identity=32.9896907216495, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17569497, Length=186, Percent_Identity=29.0322580645161, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17569499, Length=182, Percent_Identity=33.5164835164835, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17570459, Length=160, Percent_Identity=34.375, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32566490, Length=154, Percent_Identity=34.4155844155844, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193210507, Length=195, Percent_Identity=32.3076923076923, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17570161, Length=195, Percent_Identity=32.3076923076923, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71989955, Length=180, Percent_Identity=32.2222222222222, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71989948, Length=180, Percent_Identity=32.2222222222222, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17542664, Length=165, Percent_Identity=27.8787878787879, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550506, Length=272, Percent_Identity=34.9264705882353, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI18860517, Length=192, Percent_Identity=35.4166666666667, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45556022, Length=196, Percent_Identity=34.6938775510204, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24657857, Length=199, Percent_Identity=35.678391959799, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI62484274, Length=199, Percent_Identity=35.678391959799, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI62484448, Length=199, Percent_Identity=35.678391959799, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281365664, Length=199, Percent_Identity=35.678391959799, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356845, Length=200, Percent_Identity=27.5, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281361631, Length=198, Percent_Identity=28.2828282828283, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281361633, Length=198, Percent_Identity=28.2828282828283, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28573263, Length=198, Percent_Identity=25.7575757575758, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281361635, Length=140, Percent_Identity=30, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 35148; Mature: 35148

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01270 BAND_7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIFLAVFLLIGVVGLIGIVSAFKFVPQGHNWTVERFGRYTRTLTPGVSVITPFIDRIGR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KMNMMETVMEVPQQEVITKDNAMVSCDAIVFIQVIDAVQAAYEVNNLTHAISNLSMTNIR
HHHHHHHHHHCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
TVVGSMDLDQVLSNRDEINARLLGTIDAATHPWGIKVTRIEIKDLTPPADITEAMARQMK
HHHCCCCHHHHHCCHHHCCHHEEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
AERLKRAEILTAEGEKQSAILKAEGQKQAQILQAEGRKEAAFRDAEAREREAEAEAKATA
HHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
MVSEAIARGDVNAINYFLGQAYVAAFEKLATSPQQRTVIIPAEFSSILGTIEGIRGLTDA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
AKNTTAPPRPQGAVPPTRRED
HCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDIFLAVFLLIGVVGLIGIVSAFKFVPQGHNWTVERFGRYTRTLTPGVSVITPFIDRIGR
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KMNMMETVMEVPQQEVITKDNAMVSCDAIVFIQVIDAVQAAYEVNNLTHAISNLSMTNIR
HHHHHHHHHHCCHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
TVVGSMDLDQVLSNRDEINARLLGTIDAATHPWGIKVTRIEIKDLTPPADITEAMARQMK
HHHCCCCHHHHHCCHHHCCHHEEEEECCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
AERLKRAEILTAEGEKQSAILKAEGQKQAQILQAEGRKEAAFRDAEAREREAEAEAKATA
HHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
MVSEAIARGDVNAINYFLGQAYVAAFEKLATSPQQRTVIIPAEFSSILGTIEGIRGLTDA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
AKNTTAPPRPQGAVPPTRRED
HCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]