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The map label for this gene is qorA [H]

Identifier: 114799986

GI number: 114799986

Start: 7751

End: 8725

Strand: Reverse

Name: qorA [H]

Synonym: HNE_0011

Alternate gene names: 114799986

Gene position: 8725-7751 (Counterclockwise)

Preceding gene: 114800535

Following gene: 114798843

Centisome position: 0.24

GC content: 63.9

Gene sequence:

>975_bases
ATGACCGCAACAATGACGGCCGCCCATGCCGAAACCGGCCAACCCCTGAAACGGGTGGAGCGCCCCCGCCCCGTCCCCGG
ACAAGGCGAAATCCTGATCGAAGTAGCCGCAGCCGGCCTCAACCGGGCAGACCTGGCTCAGCGCGCGGGCCGTTATCCAC
CCCCACCGGGCGCCTCCGACATTCTGGGCCTGGAGGTTTCCGGTACGGTTGTGGGCCTTGGCCCTGGCACGTCACGTTTC
AAGCAGGGCGACCGGGTGTGTGCCCTGCTTGCGGGCGGAGGCTATGCCAGCCATGTGGTGGTCGATGAAGGCTCTGTGCT
GCCGGTTCCGGGGGACATGGACCTTGTGACAGCCGCCTGTTTCCCCGAGGCGCTGATGACGGCCTGGGCCAATGTGTTTG
ACCGCGCAGGCCTCAAGCCCGGCGAGACCTTCCTCTGCCACGGCGCCACCAGCGGCATCGGCGTGATGGCGATCCAGATG
GCCAAGGCCTATGGCGCGCCGAAGATTTTCGGCACGGCAGGATCTGAAGAAAAATGCGCCCTGGCGCGCGACCTGGGCGC
CGACATTGCCATCAATTACCGCGAGCAGGATTTCGAGCAGATCGTGAAGGAAGCTGGCGGCGCCGATGTGACCCTCGACA
TGGTGGGCGGCGACTACATCCAGAAGAATATCGGTGCAGCCAAGGCCGACGGGCGCATCATCAACATTGCCTATCAGAAC
GGCATGGTGGCCGAAGTGAATTTCGGGCTGGTGCTGATGAAGCGGCTGTCGCTCATGGCAACCACGCTGCGGGCACGTCC
GGTGCCGGAGAAGTCTCGCATCCGGGCGGCGGTTGAGAAGGATTTCTGGCCGCATGTGGCGAGCGGCAAAATCCGCGCGG
TCCTGGAAAAAACCTATCCGCTCGCCGAGGCCGAAGCGGCCCTCGCCCATATGGAAAAGGGCGGCCATTCGGGGAAAATC
CTGCTTACATTATAG

Upstream 100 bases:

>100_bases
GTCTCCGGGGCGTGTCTCCGTCTCATTGGTTTCATCAAAGCAGAAAGCCGGGCTAGAAGCGACTCCGAGACCCTTAATAC
CCGCGCAAGGAGTTATCCCC

Downstream 100 bases:

>100_bases
GATGCTTCCCTTGGCGGCGCATTTGGCTTATATGAAAGGTCAAGGTTCACAGTTTGCCTGAAACCTCATCCGCCCGGCAC
TCGCGTGCCGGGCGGCTGCA

Product: NAD(P)H quinone oxidoreductase PIG3 family protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTATMTAAHAETGQPLKRVERPRPVPGQGEILIEVAAAGLNRADLAQRAGRYPPPPGASDILGLEVSGTVVGLGPGTSRF
KQGDRVCALLAGGGYASHVVVDEGSVLPVPGDMDLVTAACFPEALMTAWANVFDRAGLKPGETFLCHGATSGIGVMAIQM
AKAYGAPKIFGTAGSEEKCALARDLGADIAINYREQDFEQIVKEAGGADVTLDMVGGDYIQKNIGAAKADGRIINIAYQN
GMVAEVNFGLVLMKRLSLMATTLRARPVPEKSRIRAAVEKDFWPHVASGKIRAVLEKTYPLAEAEAALAHMEKGGHSGKI
LLTL

Sequences:

>Translated_324_residues
MTATMTAAHAETGQPLKRVERPRPVPGQGEILIEVAAAGLNRADLAQRAGRYPPPPGASDILGLEVSGTVVGLGPGTSRF
KQGDRVCALLAGGGYASHVVVDEGSVLPVPGDMDLVTAACFPEALMTAWANVFDRAGLKPGETFLCHGATSGIGVMAIQM
AKAYGAPKIFGTAGSEEKCALARDLGADIAINYREQDFEQIVKEAGGADVTLDMVGGDYIQKNIGAAKADGRIINIAYQN
GMVAEVNFGLVLMKRLSLMATTLRARPVPEKSRIRAAVEKDFWPHVASGKIRAVLEKTYPLAEAEAALAHMEKGGHSGKI
LLTL
>Mature_323_residues
TATMTAAHAETGQPLKRVERPRPVPGQGEILIEVAAAGLNRADLAQRAGRYPPPPGASDILGLEVSGTVVGLGPGTSRFK
QGDRVCALLAGGGYASHVVVDEGSVLPVPGDMDLVTAACFPEALMTAWANVFDRAGLKPGETFLCHGATSGIGVMAIQMA
KAYGAPKIFGTAGSEEKCALARDLGADIAINYREQDFEQIVKEAGGADVTLDMVGGDYIQKNIGAAKADGRIINIAYQNG
MVAEVNFGLVLMKRLSLMATTLRARPVPEKSRIRAAVEKDFWPHVASGKIRAVLEKTYPLAEAEAALAHMEKGGHSGKIL
LTL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=315, Percent_Identity=39.6825396825397, Blast_Score=214, Evalue=9e-56,
Organism=Homo sapiens, GI22538444, Length=315, Percent_Identity=39.6825396825397, Blast_Score=214, Evalue=9e-56,
Organism=Homo sapiens, GI194239674, Length=306, Percent_Identity=30.718954248366, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI13236495, Length=306, Percent_Identity=30.718954248366, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24308257, Length=332, Percent_Identity=27.710843373494, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI194239676, Length=303, Percent_Identity=29.042904290429, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI18379349, Length=310, Percent_Identity=25.4838709677419, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI28557745, Length=309, Percent_Identity=28.8025889967638, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI47519420, Length=350, Percent_Identity=27.1428571428571, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41872631, Length=314, Percent_Identity=27.0700636942675, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI197927207, Length=200, Percent_Identity=31, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226059159, Length=111, Percent_Identity=36.036036036036, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI226059133, Length=111, Percent_Identity=36.036036036036, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI226056130, Length=111, Percent_Identity=36.036036036036, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790485, Length=331, Percent_Identity=33.5347432024169, Blast_Score=128, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI212642053, Length=315, Percent_Identity=26.3492063492064, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507255, Length=220, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536829, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=255, Percent_Identity=28.2352941176471, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17556000, Length=200, Percent_Identity=32, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=317, Percent_Identity=27.7602523659306, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581345, Length=324, Percent_Identity=25.6172839506173, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550423, Length=158, Percent_Identity=31.0126582278481, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33986; Mature: 33854

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATMTAAHAETGQPLKRVERPRPVPGQGEILIEVAAAGLNRADLAQRAGRYPPPPGASD
CCCCEECCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCC
ILGLEVSGTVVGLGPGTSRFKQGDRVCALLAGGGYASHVVVDEGSVLPVPGDMDLVTAAC
EEEEEECCEEEEECCCCHHHCCCCCEEEEEECCCCEEEEEEECCCEEECCCCHHHHHHHH
FPEALMTAWANVFDRAGLKPGETFLCHGATSGIGVMAIQMAKAYGAPKIFGTAGSEEKCA
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHH
LARDLGADIAINYREQDFEQIVKEAGGADVTLDMVGGDYIQKNIGAAKADGRIINIAYQN
HHHHCCCCEEEECCHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCEEEEEEECC
GMVAEVNFGLVLMKRLSLMATTLRARPVPEKSRIRAAVEKDFWPHVASGKIRAVLEKTYP
CEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
LAEAEAALAHMEKGGHSGKILLTL
HHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
TATMTAAHAETGQPLKRVERPRPVPGQGEILIEVAAAGLNRADLAQRAGRYPPPPGASD
CCCEECCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCC
ILGLEVSGTVVGLGPGTSRFKQGDRVCALLAGGGYASHVVVDEGSVLPVPGDMDLVTAAC
EEEEEECCEEEEECCCCHHHCCCCCEEEEEECCCCEEEEEEECCCEEECCCCHHHHHHHH
FPEALMTAWANVFDRAGLKPGETFLCHGATSGIGVMAIQMAKAYGAPKIFGTAGSEEKCA
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHH
LARDLGADIAINYREQDFEQIVKEAGGADVTLDMVGGDYIQKNIGAAKADGRIINIAYQN
HHHHCCCCEEEECCHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCCCEEEEEEECC
GMVAEVNFGLVLMKRLSLMATTLRARPVPEKSRIRAAVEKDFWPHVASGKIRAVLEKTYP
CEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
LAEAEAALAHMEKGGHSGKILLTL
HHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]