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The map label for this gene is moaC2 [H]

Identifier: 114799818

GI number: 114799818

Start: 1576952

End: 1577440

Strand: Direct

Name: moaC2 [H]

Synonym: HNE_1552

Alternate gene names: 114799818

Gene position: 1576952-1577440 (Clockwise)

Preceding gene: 114797493

Following gene: 114798744

Centisome position: 42.56

GC content: 62.99

Gene sequence:

>489_bases
GTGACGAAGCTGACCCACCTCGATTCTGATGGCCGCGTTCATATGGTGGATGTGAGCGAGAAGGCCGCAAGTGTGCGCCG
CGCGGTGGCGAGCGGGCGCGTGCGATGCCTGCCCGAAACGCTAGCCGCGGTGCGCGAGGCGCGCACGCCCAAGGGGGCGG
TTATCACGACGGCAGAGCTTGCCGGCATCATGGCGGCCAAGCGAACCCATGAATTGATCCCGCTCTGCCACCCGCTGATG
CTCAGCAAGGTGGCCGTTACGATAGAGATGGATGACGCCCTGCCGGGCTTCAGAATTTCCGCCGAAGTGCGACTGACCGG
CCAGACCGGCATTGAGATGGAAGCGCTGACCGCCGCGAGTGTCGCCGCGCTCACGCTCTATGACATGCTTAAAGCTGTCG
ACAAGGGTATTATCATTGAAGCGATCCGCCTTGAAGAGAAGAGCGGCGGCAAGTCCGGCGACTGGCGGGCAGAGACCGAA
GTGCCATGA

Upstream 100 bases:

>100_bases
GCCGGGACGCATGGGACCATGTGTTCGCCCTGGAGTTCGATAGCAGGTTCCGGCCGTGCTCCCTGGTCGGTCAGATTGAA
CGCTATCGGGGAATCTGTCC

Downstream 100 bases:

>100_bases
TTTCCTTCAATGAGGCACTCTCCCGCGTGATCGGCGTCGCGCTGCCATTGGGTTCTGAAAGCGTGTCCTTCGAAGCCGCA
TCGGGTCGAGTGCTTTCCGA

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MTKLTHLDSDGRVHMVDVSEKAASVRRAVASGRVRCLPETLAAVREARTPKGAVITTAELAGIMAAKRTHELIPLCHPLM
LSKVAVTIEMDDALPGFRISAEVRLTGQTGIEMEALTAASVAALTLYDMLKAVDKGIIIEAIRLEEKSGGKSGDWRAETE
VP

Sequences:

>Translated_162_residues
MTKLTHLDSDGRVHMVDVSEKAASVRRAVASGRVRCLPETLAAVREARTPKGAVITTAELAGIMAAKRTHELIPLCHPLM
LSKVAVTIEMDDALPGFRISAEVRLTGQTGIEMEALTAASVAALTLYDMLKAVDKGIIIEAIRLEEKSGGKSGDWRAETE
VP
>Mature_161_residues
TKLTHLDSDGRVHMVDVSEKAASVRRAVASGRVRCLPETLAAVREARTPKGAVITTAELAGIMAAKRTHELIPLCHPLML
SKVAVTIEMDDALPGFRISAEVRLTGQTGIEMEALTAASVAALTLYDMLKAVDKGIIIEAIRLEEKSGGKSGDWRAETEV
P

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=160, Percent_Identity=56.875, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=42.2818791946309, Blast_Score=119, Evalue=9e-28,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=47.5, Blast_Score=136, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=49.3055555555556, Blast_Score=124, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17345; Mature: 17214

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTHLDSDGRVHMVDVSEKAASVRRAVASGRVRCLPETLAAVREARTPKGAVITTAEL
CCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCEEEHHHH
AGIMAAKRTHELIPLCHPLMLSKVAVTIEMDDALPGFRISAEVRLTGQTGIEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEEEEECCCCCCEEHHHHHHH
VAALTLYDMLKAVDKGIIIEAIRLEEKSGGKSGDWRAETEVP
HHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKLTHLDSDGRVHMVDVSEKAASVRRAVASGRVRCLPETLAAVREARTPKGAVITTAEL
CCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCEEEHHHH
AGIMAAKRTHELIPLCHPLMLSKVAVTIEMDDALPGFRISAEVRLTGQTGIEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEEEEECCCCCCEEHHHHHHH
VAALTLYDMLKAVDKGIIIEAIRLEEKSGGKSGDWRAETEVP
HHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA