Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 114799792

GI number: 114799792

Start: 1402384

End: 1403286

Strand: Direct

Name: yafC [H]

Synonym: HNE_1372

Alternate gene names: 114799792

Gene position: 1402384-1403286 (Clockwise)

Preceding gene: 114800139

Following gene: 114797614

Centisome position: 37.85

GC content: 62.68

Gene sequence:

>903_bases
ATGGACGCAAAGACGGGTTCCGCCAGCGACCGGGCCCGGGCGCTGGAAGTATTCGCTGCCATCGCTTCGGAGGGCAGCTT
CTCGGCGGCGGGCAGGCGGCTGGATCTCAGCGCTTCGGCCATCAGCCGGACAGTCGACCGGATTGAGGAAAGGCTCGGCG
TGCGGCTCATTCTGCGTTCAACGCGGGCTCTGACGCTGACGGCGGAGGGGCAGGCCTATCTGAGCGCGGCAAGGCGGATA
CTCACCGACCTTGATGAGGCCGAACAGTCCATCGCCGACCAGGGCGCGCCGCGCGGGCGATTGCGTGTCAGCGCGGCGCT
GGCGCATGGGCGGCTATGCATTGTGCCCCTGCTGGGACAGTTTTCTGTGTTGTATCCGCACATCCTCGTGGACATCAGCC
TGACGGACAATGTTGTTGATATTGCCGCGGGCGAAACGGATGTGGCGATCCGGTTTGGTCCGTTAGCGGACAGTCCACTC
ATGGCGCGGAAGCTGGGAGAAAGCGGGCGGGTGATCGTAGCCTCGCCGGATTATATTGCCCGGAACGGCGCGCCCGAAAT
GCCTGAAGACCTTTACCGGCACAATTGCCTGAGTTTCAATTTCAGGCGGGCTGAGCCGGTCTGGCCCTTCCGCAAGGATG
GCCGGGACTATGCGCTGAACGTGCGGGGCAGCATCGAGGCCAATAACGGGGAAACGCTGGGCCAGCTCGCCGCCGATGGC
ATCGGTATTGCGCGCGTTGGTACTTTCAGCGTTGCTGCGGATATGGCGGCCGGAACGCTCGTTCCACTGCTGGAAGGGTA
TAATCCCGGGGACATTGAAGAAATTCATGCCGTTTTCGCTGGCGGGCCGAACACACCGGCGCGTGTAAGGGCATTTGTGG
AGTTCCTGGCGGAACATCTTTAG

Upstream 100 bases:

>100_bases
TGTCTGAAGTCCATGTTGATGCCTTTTGAATTGCGTTGGGCGCAAAGATAGACGAGGGAAAATACTATTTTAGGTGCTCT
GGATGCGAAGGACCTTTGAT

Downstream 100 bases:

>100_bases
GCTGTGTGTGGGGATTGGGGCTAGGCCGGAACGTAGGTGAGGCGGATAACTTCGGGGCCGATGCGGTCTGTCGCTGTGAG
GCGGAGGCGCGGGCGGGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDAKTGSASDRARALEVFAAIASEGSFSAAGRRLDLSASAISRTVDRIEERLGVRLILRSTRALTLTAEGQAYLSAARRI
LTDLDEAEQSIADQGAPRGRLRVSAALAHGRLCIVPLLGQFSVLYPHILVDISLTDNVVDIAAGETDVAIRFGPLADSPL
MARKLGESGRVIVASPDYIARNGAPEMPEDLYRHNCLSFNFRRAEPVWPFRKDGRDYALNVRGSIEANNGETLGQLAADG
IGIARVGTFSVAADMAAGTLVPLLEGYNPGDIEEIHAVFAGGPNTPARVRAFVEFLAEHL

Sequences:

>Translated_300_residues
MDAKTGSASDRARALEVFAAIASEGSFSAAGRRLDLSASAISRTVDRIEERLGVRLILRSTRALTLTAEGQAYLSAARRI
LTDLDEAEQSIADQGAPRGRLRVSAALAHGRLCIVPLLGQFSVLYPHILVDISLTDNVVDIAAGETDVAIRFGPLADSPL
MARKLGESGRVIVASPDYIARNGAPEMPEDLYRHNCLSFNFRRAEPVWPFRKDGRDYALNVRGSIEANNGETLGQLAADG
IGIARVGTFSVAADMAAGTLVPLLEGYNPGDIEEIHAVFAGGPNTPARVRAFVEFLAEHL
>Mature_300_residues
MDAKTGSASDRARALEVFAAIASEGSFSAAGRRLDLSASAISRTVDRIEERLGVRLILRSTRALTLTAEGQAYLSAARRI
LTDLDEAEQSIADQGAPRGRLRVSAALAHGRLCIVPLLGQFSVLYPHILVDISLTDNVVDIAAGETDVAIRFGPLADSPL
MARKLGESGRVIVASPDYIARNGAPEMPEDLYRHNCLSFNFRRAEPVWPFRKDGRDYALNVRGSIEANNGETLGQLAADG
IGIARVGTFSVAADMAAGTLVPLLEGYNPGDIEEIHAVFAGGPNTPARVRAFVEFLAEHL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=37.7162629757785, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=33.448275862069, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=31.5068493150685, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=27.7777777777778, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=28.6666666666667, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=28.4210526315789, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787589, Length=269, Percent_Identity=28.2527881040892, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789173, Length=248, Percent_Identity=31.8548387096774, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI87082132, Length=291, Percent_Identity=26.1168384879725, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788706, Length=295, Percent_Identity=25.4237288135593, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=162, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786448, Length=270, Percent_Identity=28.5185185185185, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI157672245, Length=169, Percent_Identity=31.9526627218935, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=26.5536723163842, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081904, Length=157, Percent_Identity=31.2101910828025, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32078; Mature: 32078

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKTGSASDRARALEVFAAIASEGSFSAAGRRLDLSASAISRTVDRIEERLGVRLILRS
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCEEECHHHHHHHHHHHHHHHHCEEEEEEC
TRALTLTAEGQAYLSAARRILTDLDEAEQSIADQGAPRGRLRVSAALAHGRLCIVPLLGQ
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCEEEEEHHHH
FSVLYPHILVDISLTDNVVDIAAGETDVAIRFGPLADSPLMARKLGESGRVIVASPDYIA
HHHHCCEEEEEEEECCCEEEEECCCCEEEEEECCCCCCCHHHHHCCCCCCEEEECCCHHH
RNGAPEMPEDLYRHNCLSFNFRRAEPVWPFRKDGRDYALNVRGSIEANNGETLGQLAADG
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHCC
IGIARVGTFSVAADMAAGTLVPLLEGYNPGDIEEIHAVFAGGPNTPARVRAFVEFLAEHL
CCEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDAKTGSASDRARALEVFAAIASEGSFSAAGRRLDLSASAISRTVDRIEERLGVRLILRS
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCEEECHHHHHHHHHHHHHHHHCEEEEEEC
TRALTLTAEGQAYLSAARRILTDLDEAEQSIADQGAPRGRLRVSAALAHGRLCIVPLLGQ
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCEEEEEHHHH
FSVLYPHILVDISLTDNVVDIAAGETDVAIRFGPLADSPLMARKLGESGRVIVASPDYIA
HHHHCCEEEEEEEECCCEEEEECCCCEEEEEECCCCCCCHHHHHCCCCCCEEEECCCHHH
RNGAPEMPEDLYRHNCLSFNFRRAEPVWPFRKDGRDYALNVRGSIEANNGETLGQLAADG
CCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHCC
IGIARVGTFSVAADMAAGTLVPLLEGYNPGDIEEIHAVFAGGPNTPARVRAFVEFLAEHL
CCEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]