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The map label for this gene is ftsY [H]

Identifier: 114799634

GI number: 114799634

Start: 3660286

End: 3661530

Strand: Reverse

Name: ftsY [H]

Synonym: HNE_3526

Alternate gene names: 114799634

Gene position: 3661530-3660286 (Counterclockwise)

Preceding gene: 114800325

Following gene: 114799708

Centisome position: 98.83

GC content: 64.26

Gene sequence:

>1245_bases
ATGATCCTCTGGTTCGGCAAGAAGAAGAAACTCGACGAGGCCAAAGCCGCCGGCGAGGTAATGAAAGCGCCGGAATTGAG
CGCGGAAGAAATCGCCGCGCAGGAAGCCGCTGCCCGCGAGAAGGCAGAGATTGAACGCAAGGTCGCCGAGGCAAACCAGG
CCTGGGAGGCGCGCCAGCGCCGCGAGGCCCAGGAAGCCGAAGACGAAGCCGTCCGCGCCAAGGCGGCCGCCGAGCTTAAA
CTGCTGGAAGACCGCCGGGAGCATGAGCGTCTGCGCGCCGAAGCGGCCGAGGCCGCCCGTCTCGCCGCAGAGGCCGAAGC
CAATGATCCCGGCCTCTTTGGCCGTCTGGGCGAAGGGCTCGCCCGCTCCACCGCCAAGCTCACCGAAGGTCTCGCCGCGC
TGGGCCGCCGCAAGCTTGATGACGCCACCCTTGAGGAATTGCAGGATCTGCTGATCACCTCGGATATGGGCACGCGCGTC
GCCATGCGCGTCACCAAGGGCATCGCGAAGGGGCGTTTCGACAAGGAAATCTCCGGCGAGGAAATTCGCCTCGCATTGGC
CGAGGAGATCGAGGAGATCCTCAAGCCCCGCGAACAGGTGGTTGATTTCTCCGACGGCCCGCGCCCGCGCATTGTTCTGT
TCGTCGGCGTCAACGGATCAGGCAAGACGACCACCATCGGCAAGATCGCTTCGAAACTTCAGGAACAGGGCGCCAAGGCG
CTGCTGGTTGCCGGGGACACTTTCCGCGCGGCTGCTGTCGAGCAGCTTAAAGTGTGGGGCGAGCGCGCCGGTATTCCCGT
TATGGCAGGCGCCCATGGCGCGGATGCGGCGGGCCTCGTCTATGGCGCGGTGGAGCGGGCGAAAGCCGAGGATCTGGACC
TTGTGCTGGTCGATACCGCCGGGCGCCTGCAAAACAAGGCCGAGCTGATGTCAGAGCTCGGCAAGATCGTCCGTGTCATG
AAGAAAATTGATCCCGATGCCCCGCATGATGTGATCCTCGTGCTCGATGCCACGGTCGGTCAGAATGCGCTCTCCCAGGT
CGAAGCCTTCCGCCATACTGCCGGGGTGACTGGCCTGGTGATGACCAAGCTGGACGGTACCGCCAAAGGCGGCGTGCTGG
TGGCGATTGCCGAAGCGCACGACCTGCCCATCCATTTCATTGGTATTGGCGAGCGGGCCGAAGACCTCCGCCCGTTCAGT
GCGGAGGCCTTCGCCAAGGCGTTGGTTGGTATCAAGGCGAGCTGA

Upstream 100 bases:

>100_bases
CCCAGGTCAAACTCAGTCGCGCGGCAGGGGAGGGTGGACGGATGACGCCTGTGCAGATAACCGGCCATGACGGCAAGCAG
CTTCTGGGAACACCCCTTTC

Downstream 100 bases:

>100_bases
CGCCTACTCCGCCGCCATCGCCTGCGCCGGGGCCTGGCGCGCCCCGCGGACGAGGTTGCCGGGGAGTTTCCCGGTCGGGT
CGCCGTCCCGGTGGGTGATC

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MILWFGKKKKLDEAKAAGEVMKAPELSAEEIAAQEAAAREKAEIERKVAEANQAWEARQRREAQEAEDEAVRAKAAAELK
LLEDRREHERLRAEAAEAARLAAEAEANDPGLFGRLGEGLARSTAKLTEGLAALGRRKLDDATLEELQDLLITSDMGTRV
AMRVTKGIAKGRFDKEISGEEIRLALAEEIEEILKPREQVVDFSDGPRPRIVLFVGVNGSGKTTTIGKIASKLQEQGAKA
LLVAGDTFRAAAVEQLKVWGERAGIPVMAGAHGADAAGLVYGAVERAKAEDLDLVLVDTAGRLQNKAELMSELGKIVRVM
KKIDPDAPHDVILVLDATVGQNALSQVEAFRHTAGVTGLVMTKLDGTAKGGVLVAIAEAHDLPIHFIGIGERAEDLRPFS
AEAFAKALVGIKAS

Sequences:

>Translated_414_residues
MILWFGKKKKLDEAKAAGEVMKAPELSAEEIAAQEAAAREKAEIERKVAEANQAWEARQRREAQEAEDEAVRAKAAAELK
LLEDRREHERLRAEAAEAARLAAEAEANDPGLFGRLGEGLARSTAKLTEGLAALGRRKLDDATLEELQDLLITSDMGTRV
AMRVTKGIAKGRFDKEISGEEIRLALAEEIEEILKPREQVVDFSDGPRPRIVLFVGVNGSGKTTTIGKIASKLQEQGAKA
LLVAGDTFRAAAVEQLKVWGERAGIPVMAGAHGADAAGLVYGAVERAKAEDLDLVLVDTAGRLQNKAELMSELGKIVRVM
KKIDPDAPHDVILVLDATVGQNALSQVEAFRHTAGVTGLVMTKLDGTAKGGVLVAIAEAHDLPIHFIGIGERAEDLRPFS
AEAFAKALVGIKAS
>Mature_414_residues
MILWFGKKKKLDEAKAAGEVMKAPELSAEEIAAQEAAAREKAEIERKVAEANQAWEARQRREAQEAEDEAVRAKAAAELK
LLEDRREHERLRAEAAEAARLAAEAEANDPGLFGRLGEGLARSTAKLTEGLAALGRRKLDDATLEELQDLLITSDMGTRV
AMRVTKGIAKGRFDKEISGEEIRLALAEEIEEILKPREQVVDFSDGPRPRIVLFVGVNGSGKTTTIGKIASKLQEQGAKA
LLVAGDTFRAAAVEQLKVWGERAGIPVMAGAHGADAAGLVYGAVERAKAEDLDLVLVDTAGRLQNKAELMSELGKIVRVM
KKIDPDAPHDVILVLDATVGQNALSQVEAFRHTAGVTGLVMTKLDGTAKGGVLVAIAEAHDLPIHFIGIGERAEDLRPFS
AEAFAKALVGIKAS

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=230, Percent_Identity=35.2173913043478, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4507215, Length=230, Percent_Identity=35.2173913043478, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI295424842, Length=336, Percent_Identity=32.4404761904762, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI23308697, Length=336, Percent_Identity=32.4404761904762, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI89061728, Length=128, Percent_Identity=36.71875, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789874, Length=300, Percent_Identity=48.3333333333333, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1788963, Length=306, Percent_Identity=30.718954248366, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=279, Percent_Identity=32.9749103942652, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI193206261, Length=310, Percent_Identity=30.9677419354839, Blast_Score=134, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6325345, Length=204, Percent_Identity=39.2156862745098, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6320498, Length=231, Percent_Identity=31.6017316017316, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17647949, Length=276, Percent_Identity=32.6086956521739, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24641198, Length=303, Percent_Identity=30.3630363036304, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 44345; Mature: 44345

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILWFGKKKKLDEAKAAGEVMKAPELSAEEIAAQEAAAREKAEIERKVAEANQAWEARQR
CEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REAQEAEDEAVRAKAAAELKLLEDRREHERLRAEAAEAARLAAEAEANDPGLFGRLGEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ARSTAKLTEGLAALGRRKLDDATLEELQDLLITSDMGTRVAMRVTKGIAKGRFDKEISGE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCH
EIRLALAEEIEEILKPREQVVDFSDGPRPRIVLFVGVNGSGKTTTIGKIASKLQEQGAKA
HHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCE
LLVAGDTFRAAAVEQLKVWGERAGIPVMAGAHGADAAGLVYGAVERAKAEDLDLVLVDTA
EEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCC
GRLQNKAELMSELGKIVRVMKKIDPDAPHDVILVLDATVGQNALSQVEAFRHTAGVTGLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEE
MTKLDGTAKGGVLVAIAEAHDLPIHFIGIGERAEDLRPFSAEAFAKALVGIKAS
EEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MILWFGKKKKLDEAKAAGEVMKAPELSAEEIAAQEAAAREKAEIERKVAEANQAWEARQR
CEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REAQEAEDEAVRAKAAAELKLLEDRREHERLRAEAAEAARLAAEAEANDPGLFGRLGEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ARSTAKLTEGLAALGRRKLDDATLEELQDLLITSDMGTRVAMRVTKGIAKGRFDKEISGE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCH
EIRLALAEEIEEILKPREQVVDFSDGPRPRIVLFVGVNGSGKTTTIGKIASKLQEQGAKA
HHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCE
LLVAGDTFRAAAVEQLKVWGERAGIPVMAGAHGADAAGLVYGAVERAKAEDLDLVLVDTA
EEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCC
GRLQNKAELMSELGKIVRVMKKIDPDAPHDVILVLDATVGQNALSQVEAFRHTAGVTGLV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEE
MTKLDGTAKGGVLVAIAEAHDLPIHFIGIGERAEDLRPFSAEAFAKALVGIKAS
EEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]