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The map label for this gene is engD [H]

Identifier: 114799588

GI number: 114799588

Start: 1994021

End: 1995118

Strand: Direct

Name: engD [H]

Synonym: HNE_1924

Alternate gene names: 114799588

Gene position: 1994021-1995118 (Clockwise)

Preceding gene: 114798056

Following gene: 114797679

Centisome position: 53.82

GC content: 60.93

Gene sequence:

>1098_bases
ATGGGCTTCAAATGCGGTATCGTTGGCCTGCCGAATGTCGGCAAGTCCACCCTTTTCAATGCTCTGACGCAGACAGCAGC
CGCTCAGGCCGCCAATTATCCGTTCTGTACCATTGAGCCGAACGTTGGAGAAGTGGCAGTCCCGGAAGCCCGGCTGACCA
AGCTGGCCGCCGTGGCCGGGTCGAAGGAAATCATTCCCGCCCGCATGAACTTCGTCGACATTGCCGGCCTGGTCGAAGGC
GCCAGCCAGGGCGAGGGCCTCGGCAACAAATTCCTCGCCAACATCCGCGAGACGGACGCCGTGATCTACGTCCTGCGCTG
TTTCGAGAATGACGACATCACCCATGTCCGCGGCAAGGTGGACCCCATCGCAGACTTCGAGATCGTCGAGACCGAACTGA
TGCTGGCCGACCTCGAGAGCCTCGAGAAGCGCAAGGCCAACATCGTCAAGCGCGCCAACACGGGTGACAAGGAAGCCAAG
GCACAGGTCGCCCTGATGGATCTGGCGCTGAACGAGCTGCGTGAAGGCCGCCCTGCCCGCTATGCGAAAGTGCCGGCCGA
CGACGTCAAAGCCTGGAACATGCTCCAGCTCCTCACGGCAAAGCCGATCCTGTTTGTCGCCAATGTGGACGAGGCAAGCG
CGGCGACGGGCAATGCCTTCTCGAAGCTTGTTGAAGAGCGCGCCAAGAAGGAAGGCGCTCTGGCCGTCGTCATCTCGGCG
CAGATCGAGTCCGAACTGGCCATGCTGGACGAAGCAGAGGGCAAGGAATTCCTTGAAACCCTTGGCCTGGAAGAGCCTGG
CCTCACGCGCCTCATCCGCACCGGCTATGAGCTGCTTGGCCTGCAGACCTATTTCACCGCCGGGCCGAAAGAAAGCCGCG
CGTGGACCATCCGGAAGGGCTGGACGGCGCCAAAGGCTGCCGGTGTGATCCATGGTGATTTCGAGAAAGGTTTCATCCGC
GCCGAAACCATCGCCTTTGAAGACTATGTCGCCTGTGGCGGCGAAGTGGGCGCCAAGGAAGCCGGCAAGATGCGCTCGGA
AGGCAAGGAATACATTGTTCAGGACGGCGATGTGATGCTGTTCCGCTTCAACGTCTGA

Upstream 100 bases:

>100_bases
TGAACGCCAGTCCCGCTGCATCCTAGCGATTTTTGTGCCTGTTTTTCAGCTGCGAAAGCGGCTAAGGCGCCCTTTCAGGA
ATTTTAGAGGTATTCGCCCC

Downstream 100 bases:

>100_bases
AGCAGGAACGCTTTCCAAAGAAAAAGGCCGGGCCTCGATGAGGTCCGGCTTTTTTCTTGTGCACCAGTTAATGCGTCCGC
GTTACGGCATTGCCTCAAAG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPEARLTKLAAVAGSKEIIPARMNFVDIAGLVEG
ASQGEGLGNKFLANIRETDAVIYVLRCFENDDITHVRGKVDPIADFEIVETELMLADLESLEKRKANIVKRANTGDKEAK
AQVALMDLALNELREGRPARYAKVPADDVKAWNMLQLLTAKPILFVANVDEASAATGNAFSKLVEERAKKEGALAVVISA
QIESELAMLDEAEGKEFLETLGLEEPGLTRLIRTGYELLGLQTYFTAGPKESRAWTIRKGWTAPKAAGVIHGDFEKGFIR
AETIAFEDYVACGGEVGAKEAGKMRSEGKEYIVQDGDVMLFRFNV

Sequences:

>Translated_365_residues
MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPEARLTKLAAVAGSKEIIPARMNFVDIAGLVEG
ASQGEGLGNKFLANIRETDAVIYVLRCFENDDITHVRGKVDPIADFEIVETELMLADLESLEKRKANIVKRANTGDKEAK
AQVALMDLALNELREGRPARYAKVPADDVKAWNMLQLLTAKPILFVANVDEASAATGNAFSKLVEERAKKEGALAVVISA
QIESELAMLDEAEGKEFLETLGLEEPGLTRLIRTGYELLGLQTYFTAGPKESRAWTIRKGWTAPKAAGVIHGDFEKGFIR
AETIAFEDYVACGGEVGAKEAGKMRSEGKEYIVQDGDVMLFRFNV
>Mature_364_residues
GFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPEARLTKLAAVAGSKEIIPARMNFVDIAGLVEGA
SQGEGLGNKFLANIRETDAVIYVLRCFENDDITHVRGKVDPIADFEIVETELMLADLESLEKRKANIVKRANTGDKEAKA
QVALMDLALNELREGRPARYAKVPADDVKAWNMLQLLTAKPILFVANVDEASAATGNAFSKLVEERAKKEGALAVVISAQ
IESELAMLDEAEGKEFLETLGLEEPGLTRLIRTGYELLGLQTYFTAGPKESRAWTIRKGWTAPKAAGVIHGDFEKGFIRA
ETIAFEDYVACGGEVGAKEAGKMRSEGKEYIVQDGDVMLFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=43.360433604336, Blast_Score=287, Evalue=9e-78,
Organism=Homo sapiens, GI58761502, Length=216, Percent_Identity=37.962962962963, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1787454, Length=365, Percent_Identity=57.8082191780822, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=31.25, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=369, Percent_Identity=42.0054200542005, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17552324, Length=199, Percent_Identity=24.6231155778894, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=38.3783783783784, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=36.4829396325459, Blast_Score=230, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6321649, Length=159, Percent_Identity=38.9937106918239, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24640873, Length=371, Percent_Identity=44.4743935309973, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24640877, Length=371, Percent_Identity=44.4743935309973, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24640875, Length=371, Percent_Identity=44.4743935309973, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=42.3312883435583, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24585318, Length=158, Percent_Identity=31.0126582278481, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39520; Mature: 39388

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPEARLTKLAAVAG
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCHHHHHHHHHHCC
SKEIIPARMNFVDIAGLVEGASQGEGLGNKFLANIRETDAVIYVLRCFENDDITHVRGKV
CCCCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEECCCC
DPIADFEIVETELMLADLESLEKRKANIVKRANTGDKEAKAQVALMDLALNELREGRPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
YAKVPADDVKAWNMLQLLTAKPILFVANVDEASAATGNAFSKLVEERAKKEGALAVVISA
EECCCHHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCHHHHHHHHHHHHCCCCEEEEEEH
QIESELAMLDEAEGKEFLETLGLEEPGLTRLIRTGYELLGLQTYFTAGPKESRAWTIRKG
HHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHCCHHHHCCHHEECCCCCCCCEEEEECC
WTAPKAAGVIHGDFEKGFIRAETIAFEDYVACGGEVGAKEAGKMRSEGKEYIVQDGDVML
CCCCCCCCEEECCCCCCEEEEEEEEHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCEEE
FRFNV
EEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGEVAVPEARLTKLAAVAG
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCHHHHHHHHHHCC
SKEIIPARMNFVDIAGLVEGASQGEGLGNKFLANIRETDAVIYVLRCFENDDITHVRGKV
CCCCCCHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEECCCC
DPIADFEIVETELMLADLESLEKRKANIVKRANTGDKEAKAQVALMDLALNELREGRPAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
YAKVPADDVKAWNMLQLLTAKPILFVANVDEASAATGNAFSKLVEERAKKEGALAVVISA
EECCCHHHHHHHHHHHHHHCCCEEEEEECCHHCCCCCHHHHHHHHHHHHCCCCEEEEEEH
QIESELAMLDEAEGKEFLETLGLEEPGLTRLIRTGYELLGLQTYFTAGPKESRAWTIRKG
HHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHCCHHHHCCHHEECCCCCCCCEEEEECC
WTAPKAAGVIHGDFEKGFIRAETIAFEDYVACGGEVGAKEAGKMRSEGKEYIVQDGDVML
CCCCCCCCEEECCCCCCEEEEEEEEHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCEEE
FRFNV
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA