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The map label for this gene is murC [H]

Identifier: 114799440

GI number: 114799440

Start: 1146377

End: 1147786

Strand: Reverse

Name: murC [H]

Synonym: HNE_1136

Alternate gene names: 114799440

Gene position: 1147786-1146377 (Counterclockwise)

Preceding gene: 114797248

Following gene: 114797450

Centisome position: 30.98

GC content: 67.3

Gene sequence:

>1410_bases
ATGACTCACCCCACGCGCTACTTCTTTTGCGGCATCGGCGGCTCCGGCATGTTGCCGCTGGCGTTGATCCTGCTCGATCA
GGGCCACATCATCGAAGGCTCGGACCGGTCGCTCGATCAGGGGCGCACGCAAGCAAAGTTTGACTATCTGCGCAGCAAGG
GCATCCGCCTTTTCCCGCAGGATGGCAGCGGCGTGACGAGCGCCGAGCAGGTCGTCGTGGCATCGGCCGCCGTGGAAGAC
ACTGTGCCCGATATTGCCGCCGCCCTGCGCGTCGGCGCGCGGCGGATGAGCCGGGCGCAGATGCTGTCTGCCCTCTTCAA
CGCCGCGCCCACAGCCATCGGCGTGGCGGGTACGAGCGGCAAGTCCACCACCACCGGTATGATCGCCTGGATACTCCACC
ACGCCGGCAAAAGCCCGACCGTGATGAACGGCGCCGTGATGAAGAACTTCCAGACACCGGACGCCCTCTTCGCCAGCTCG
CTGGTGGGCGCCAGCGGCATCTTCGTCTCCGAAGTGGACGAAAGCGACGGCTCGATTGCCGGGTACAACCCGCGCGTTGC
GGTCGTCTCGAACATCTCGCTCGACCATAAATCCATGGACGAGTTGCGCGCCCTCTTCGGCGGCTTTGCGGCCCGCGCCG
AAACCGTCGTGCTGAACCTCGACAATGACGAGACCGCGCGGATGGCCGGGGACTTTCCGGGGGCGGTCACCTACAGCCTC
GAGAACCCCGCCGCCCGCCTCACGGCGCAGAACATCGCGCCCGCGCCCACCCACATCACTTTCTCCGTACACGACCAGAC
ATCCGGCGCCACCGCCCCCATTCGCCTCGCCACGCCGGGGCGCCACAACGTCTCAAACGTGCTGGCCGCTATTGCCGCCA
CGCTCGCCTGCGGCGTCACGCTGGCAGAGGCTGCCAAGGCTCTCGCCAGCTTCGCGGGCATCTCCCGCCGCTTCGATGTA
ATCGGCACGGAAGGCGGCGTGACGGTCATCGACGATTTCGGGCACAACCCGGACAAGATCGCCGCCACCCTGCGCACCGT
GAACCAGTTCCCCGGCCGCGTGCTGGTGATGTTCCAGCCCCACGGCTTTGGCCCCTTGCGCAACATGCGGCGCGAGTTTG
CGGCCTGTTTTGCCGAGAATCTGGACGCCGAAGACATCCTCCTGATGCCCGAGCCGGCTTACTTCGGCGGCACAGTAGAC
CGCTCGGTCGGCAGCCAGGACCTTGCCGCAGACATCCGCGCCCTTGGCCGCGAGGCCCACGCGCTGGGCGACCGGGCCGC
CTGCGGCGCGCGCCTGTTCGAACTGGCAAAGCCGGGCGACCGCATCCTCGTCATGGGCGCCCGCGATGATACCCTCACCG
TCTTCGCGCAGGAATTGCTCGCCACCTTCAAGGCGCGCGCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CCCGCTCGAGATGTGAGTTTCAAATAGTTATGCGCGATACGAAAAGTAACATAATTCACTGATGTGTAGCTCTACATCCC
CCTGTTATAAGCTCCCAACC

Downstream 100 bases:

>100_bases
AAAACTCCAACGGCGTTGGAGTTTTTTTGGAGGCTTTTCAGGCCCCGCCGCCCTGCCCGATATAGCCCAGCGTGGTGGCC
AGACGGATCGTCTGAGAGCG

Product: putative UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTHPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQDGSGVTSAEQVVVASAAVED
TVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSGKSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASS
LVGASGIFVSEVDESDGSIAGYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL
ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVTLAEAAKALASFAGISRRFDV
IGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQPHGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVD
RSVGSQDLAADIRALGREAHALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA

Sequences:

>Translated_469_residues
MTHPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQDGSGVTSAEQVVVASAAVED
TVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSGKSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASS
LVGASGIFVSEVDESDGSIAGYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL
ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVTLAEAAKALASFAGISRRFDV
IGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQPHGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVD
RSVGSQDLAADIRALGREAHALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA
>Mature_468_residues
THPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQDGSGVTSAEQVVVASAAVEDT
VPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSGKSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASSL
VGASGIFVSEVDESDGSIAGYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSLE
NPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVTLAEAAKALASFAGISRRFDVI
GTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQPHGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVDR
SVGSQDLAADIRALGREAHALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1790680, Length=460, Percent_Identity=28.2608695652174, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786279, Length=392, Percent_Identity=31.8877551020408, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49239; Mature: 49108

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQ
CCCCCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCEEEEC
DGSGVTSAEQVVVASAAVEDTVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
KSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASSLVGASGIFVSEVDESDGSIA
CCCHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEE
GYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCCEEEEEC
ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVT
CCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
LAEAAKALASFAGISRRFDVIGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQP
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
HGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVDRSVGSQDLAADIRALGREAH
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA
HCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
THPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQ
CCCCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCEEEEC
DGSGVTSAEQVVVASAAVEDTVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
KSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASSLVGASGIFVSEVDESDGSIA
CCCHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEE
GYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCCEEEEEC
ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVT
CCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
LAEAAKALASFAGISRRFDVIGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQP
HHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
HGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVDRSVGSQDLAADIRALGREAH
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA
HCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA