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The map label for this gene is pntB [H]

Identifier: 114797248

GI number: 114797248

Start: 1149318

End: 1150736

Strand: Reverse

Name: pntB [H]

Synonym: HNE_1138

Alternate gene names: 114797248

Gene position: 1150736-1149318 (Counterclockwise)

Preceding gene: 114799782

Following gene: 114799440

Centisome position: 31.06

GC content: 63.21

Gene sequence:

>1419_bases
TTGGAACAGTTCAACTCGACCTGGGCGCCCCTGCTCTATCTCGTCTCGGGCATCCTCTTCATCCTGGCCCTGCGCGGCCT
TTCCAGCCCGGCCACCAGCCAGAAGGGCAACCGCAACGGCATGATCGGCATGACGATCGCCGTGGCCACAACCATTGTCC
TCCTCTGGGAGTCGCTTGATCCGGCCACCTGGGCCCTGATGATCGGCGCGGTTGCCGTCGGCGGTACCGTCGGCGCCATT
ATCGCCCGCAAGATCCCGATGACGGACATGCCCCAGCTTGTTGCGGCCTTCCACTCGCTCGTCGGCCTTGCCGCCGTGCT
GGTGGCGTCCGCCGCGCTCTACGCCCCGTCCAGCTTCGGCATCCTCGGCATCACCGGCATCAACCCGGTCTCGCTGATCG
AGCTTGGCCTCGGCTCGGCCATCGGCGCGCTCACCTTCACCGGCTCGATCATCGCCTTTGCCAAGCTTAACGGCAATATG
AGCGGCGCGCCGATCCTGCTGCCCGCGCGTCACCTGCTCAATATCGCGCTCGGCGTGGGCATCATCGCCCTCATGGTCAT
CCTGATCCAGTCGAACGGGACGGCCCATTGGGCCTTCTGGGGCCTCACCGCCCTGGCGCTCATCCTCGGCATCACGCTCA
TCATCCCGATCGGCGGGGCAGACATGCCCGTCGTCGTCTCGATGCTGAACTCCTATTCCGGCTGGGCCGCAGCGGCGCTG
GGCTTCACGCTCGGCAACTTCGCCCTGATCATCACCGGCGCGCTGGTGGGCTCCTCAGGCGCCATCCTCTCCTACATCAT
GTGCAAAGGCATGAACCGCAGCTTCATCTCGGTCATCCTCGGCGGCTTTGGCGGAGAAGATGCAGCGGCGGCCACGGGCG
GCGTGAAAGTCGACCGGCCGTTCAAGCGCGGCTCGGCAGAAGACGCCGCCTTCATCATGAAGAATGCTTCGAAGGTCATC
ATCGTGCCGGGCTACGGCATGGCGGTCGCCCAGGCCCAGCACGCGCTGAAGGAAATGGCCGAAAAGCTGAAAGAAGAAGG
CGTCGAAGTGAAATACGCCATCCACCCCGTCGCGGGCCGGATGCCGGGTCACATGAACGTCCTCCTCGCCGAAGCGCAGG
TGCCTTACGATGAGGTGTTCGAACTCGAAGACATCAACTCGGAGTTCAACTCCTCCGACGTTGCCTTCGTCATCGGCGCA
AACGACGTGACCAACCCCGCCGCGAAGACGGACAAGACCTCGCCGATCTATGGCATGCCCATCCTCGACGTGGAAAACGC
CCGCACGGTGCTGTTCATCAAGCGCTCGATGGGCTCAGGCTATGCCGGTATCGAGAACGAGCTGTTCTTCAACGACAACA
CGATGATGCTTCTGGCCGACGCGAAGAAGATGGTCGAGGATATCGTCAAGAACCTCTGA

Upstream 100 bases:

>100_bases
TCGGCGCCATCGCCGTGGCCCTTGCCAGCGTCAACATCTTCGGCGGCTTCCTCGTCACCCAGCGCATGCTGGCCATGTAT
AAGAAGAAGGGGCAGTAGTC

Downstream 100 bases:

>100_bases
TCGGCCATCCGCACTCAAACAAAAAGGCGGGCTCGCAAATGCGATGCCCGCCTTTTTTATGCCCCCACGCCCCGCGCCCC
GAACACCACAATCTTGTTCC

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MEQFNSTWAPLLYLVSGILFILALRGLSSPATSQKGNRNGMIGMTIAVATTIVLLWESLDPATWALMIGAVAVGGTVGAI
IARKIPMTDMPQLVAAFHSLVGLAAVLVASAALYAPSSFGILGITGINPVSLIELGLGSAIGALTFTGSIIAFAKLNGNM
SGAPILLPARHLLNIALGVGIIALMVILIQSNGTAHWAFWGLTALALILGITLIIPIGGADMPVVVSMLNSYSGWAAAAL
GFTLGNFALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEDAAAATGGVKVDRPFKRGSAEDAAFIMKNASKVI
IVPGYGMAVAQAQHALKEMAEKLKEEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFNSSDVAFVIGA
NDVTNPAAKTDKTSPIYGMPILDVENARTVLFIKRSMGSGYAGIENELFFNDNTMMLLADAKKMVEDIVKNL

Sequences:

>Translated_472_residues
MEQFNSTWAPLLYLVSGILFILALRGLSSPATSQKGNRNGMIGMTIAVATTIVLLWESLDPATWALMIGAVAVGGTVGAI
IARKIPMTDMPQLVAAFHSLVGLAAVLVASAALYAPSSFGILGITGINPVSLIELGLGSAIGALTFTGSIIAFAKLNGNM
SGAPILLPARHLLNIALGVGIIALMVILIQSNGTAHWAFWGLTALALILGITLIIPIGGADMPVVVSMLNSYSGWAAAAL
GFTLGNFALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEDAAAATGGVKVDRPFKRGSAEDAAFIMKNASKVI
IVPGYGMAVAQAQHALKEMAEKLKEEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFNSSDVAFVIGA
NDVTNPAAKTDKTSPIYGMPILDVENARTVLFIKRSMGSGYAGIENELFFNDNTMMLLADAKKMVEDIVKNL
>Mature_472_residues
MEQFNSTWAPLLYLVSGILFILALRGLSSPATSQKGNRNGMIGMTIAVATTIVLLWESLDPATWALMIGAVAVGGTVGAI
IARKIPMTDMPQLVAAFHSLVGLAAVLVASAALYAPSSFGILGITGINPVSLIELGLGSAIGALTFTGSIIAFAKLNGNM
SGAPILLPARHLLNIALGVGIIALMVILIQSNGTAHWAFWGLTALALILGITLIIPIGGADMPVVVSMLNSYSGWAAAAL
GFTLGNFALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEDAAAATGGVKVDRPFKRGSAEDAAFIMKNASKVI
IVPGYGMAVAQAQHALKEMAEKLKEEGVEVKYAIHPVAGRMPGHMNVLLAEAQVPYDEVFELEDINSEFNSSDVAFVIGA
NDVTNPAAKTDKTSPIYGMPILDVENARTVLFIKRSMGSGYAGIENELFFNDNTMMLLADAKKMVEDIVKNL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=460, Percent_Identity=46.9565217391304, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI122939153, Length=460, Percent_Identity=46.9565217391304, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1787886, Length=466, Percent_Identity=52.7896995708155, Blast_Score=446, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17550456, Length=473, Percent_Identity=47.568710359408, Blast_Score=386, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49272; Mature: 49272

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFNSTWAPLLYLVSGILFILALRGLSSPATSQKGNRNGMIGMTIAVATTIVLLWESLD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCC
PATWALMIGAVAVGGTVGAIIARKIPMTDMPQLVAAFHSLVGLAAVLVASAALYAPSSFG
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ILGITGINPVSLIELGLGSAIGALTFTGSIIAFAKLNGNMSGAPILLPARHLLNIALGVG
EEEECCCCHHHHHHHHHCHHHHHHHHHCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHH
IIALMVILIQSNGTAHWAFWGLTALALILGITLIIPIGGADMPVVVSMLNSYSGWAAAAL
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCHHHHHH
GFTLGNFALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEDAAAATGGVKVDRP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHCCCCEEECCC
FKRGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALKEMAEKLKEEGVEVKYAIHPVAGR
CCCCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
MPGHMNVLLAEAQVPYDEVFELEDINSEFNSSDVAFVIGANDVTNPAAKTDKTSPIYGMP
CCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
ILDVENARTVLFIKRSMGSGYAGIENELFFNDNTMMLLADAKKMVEDIVKNL
EEECCCCCEEEEEEECCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQFNSTWAPLLYLVSGILFILALRGLSSPATSQKGNRNGMIGMTIAVATTIVLLWESLD
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCC
PATWALMIGAVAVGGTVGAIIARKIPMTDMPQLVAAFHSLVGLAAVLVASAALYAPSSFG
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ILGITGINPVSLIELGLGSAIGALTFTGSIIAFAKLNGNMSGAPILLPARHLLNIALGVG
EEEECCCCHHHHHHHHHCHHHHHHHHHCCEEEEEEECCCCCCCEEEECHHHHHHHHHHHH
IIALMVILIQSNGTAHWAFWGLTALALILGITLIIPIGGADMPVVVSMLNSYSGWAAAAL
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCHHHHHH
GFTLGNFALIITGALVGSSGAILSYIMCKGMNRSFISVILGGFGGEDAAAATGGVKVDRP
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHCCCCEEECCC
FKRGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALKEMAEKLKEEGVEVKYAIHPVAGR
CCCCCCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
MPGHMNVLLAEAQVPYDEVFELEDINSEFNSSDVAFVIGANDVTNPAAKTDKTSPIYGMP
CCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
ILDVENARTVLFIKRSMGSGYAGIENELFFNDNTMMLLADAKKMVEDIVKNL
EEECCCCCEEEEEEECCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]