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The map label for this gene is alr2 [H]

Identifier: 114799438

GI number: 114799438

Start: 2524367

End: 2525557

Strand: Reverse

Name: alr2 [H]

Synonym: HNE_2417

Alternate gene names: 114799438

Gene position: 2525557-2524367 (Counterclockwise)

Preceding gene: 114797354

Following gene: 114800200

Centisome position: 68.17

GC content: 66.41

Gene sequence:

>1191_bases
ATGGTCACTGAGGCAGCCGCGCCGGCGTCTCACTTCCAGATTGAGCATACAAGCACCTGGCATCCGTCTACGGATGAGGC
CGGCCGGCTGACAATTGATATGGGCGCCATCGCCGCCAATTACCGCCGTCTGCGTGCAATGCACCCGGCCGCGCGCGTCG
CCGCCGTTGTGAAGGCCGATGCCTATGGCCTCGATGCCACGCAGATCGCCCCCATGCTGGCCGGGCAGGGCGCGCGGGAC
TTCTTCGTTGCCCATCTCGCCGAAGCGCTGGTTCTGAAACCGCTCCTGCCGCCCGATGCTGTCCTCTTCGTCCTCAACGG
CCTCGCCCCCGGCAGTGAACCGCTTTGCGCCGAGGCGGGTATATTGCCCGTACTCAACACGCCTGAACAGGCGCGCGCCT
GGTACACGCTGGCGGTGAACAAGGCCCATCCGGTTCCCGCCGCGCTCCAGGTAGACACCGGCATGTCCCGCCTCGGCCTC
AGCGAGGGTGAACTTAACGACGTTCTTGGCTGGCCAAGCTTTGCCGGTCAGGTAAACATCTGCCTCCTGATGACGCATAT
GGCCTGCGCAGACACGCCCGGCGCCCCCGCCAACGCAGATCAGATGCGTCGCTTCGCCGACTTTGCAGCGCGCCTGCCAT
CGGTCCCCCGCTCCCTCGCCAATTCCGCTGCCGCGATGTTCCTTCCGGAGGCAGCCGGCGACGTCCTGCGCCCCGGCCTC
GTCCTCTACGGCGTCGATCCGGGCGCAGGCGGCGTGCCGAAAATGCAGCCAGCGATCGCTCTAGAAGCGCGGATCATCCA
GCTCCGCCACATTCCAGCGGGTGCCGGAGTCGGCTACGGCTTCGACTACATTGCGGACCGCCCCCTCCGCGTCGCTACGC
TTTCCGCTGGCTACGCAGACGGTTGGCCCCGCGCGCTCAGCAACGGGGGCGCCACCTGGTTCGCAGGCCACCGCCTGCCC
ATCCTCGGGCGCGTCTCCATGGACAGCTGCATGGTGGACGTGACGAACCTTCCAGAAGGAAGTATCCGCCCCGGAGACTG
TGTGGAGCTCATCGGTCCGCACCAGTCCGTCAACGATCTCGCCCGCCAACTCGCCACCACCCCCCACGAAATCCTCACCA
GCCTGGGGCGCCGTTTCACCCGCAGCTATATCAACCCCCCGTCCTTGCACGGAGAAGAGGCGCAGTCATGA

Upstream 100 bases:

>100_bases
GACCACACGATTGAAGTCGCTGACGACGCCTTCAAATTCGTGCGCGACGCGGGCACGCTGCCCCGTATCGAAAAACTGGC
CATCCTCGGGCTGCTCACGG

Downstream 100 bases:

>100_bases
AAGTAGTCATCCTGGGCGCCGGTGTCATCGGCATCACAACCGCCTACTATGCCGCGCGCGATGGCCATGACGTCACCGTG
GTAGACCGCATGAGCGGCCC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MVTEAAAPASHFQIEHTSTWHPSTDEAGRLTIDMGAIAANYRRLRAMHPAARVAAVVKADAYGLDATQIAPMLAGQGARD
FFVAHLAEALVLKPLLPPDAVLFVLNGLAPGSEPLCAEAGILPVLNTPEQARAWYTLAVNKAHPVPAALQVDTGMSRLGL
SEGELNDVLGWPSFAGQVNICLLMTHMACADTPGAPANADQMRRFADFAARLPSVPRSLANSAAAMFLPEAAGDVLRPGL
VLYGVDPGAGGVPKMQPAIALEARIIQLRHIPAGAGVGYGFDYIADRPLRVATLSAGYADGWPRALSNGGATWFAGHRLP
ILGRVSMDSCMVDVTNLPEGSIRPGDCVELIGPHQSVNDLARQLATTPHEILTSLGRRFTRSYINPPSLHGEEAQS

Sequences:

>Translated_396_residues
MVTEAAAPASHFQIEHTSTWHPSTDEAGRLTIDMGAIAANYRRLRAMHPAARVAAVVKADAYGLDATQIAPMLAGQGARD
FFVAHLAEALVLKPLLPPDAVLFVLNGLAPGSEPLCAEAGILPVLNTPEQARAWYTLAVNKAHPVPAALQVDTGMSRLGL
SEGELNDVLGWPSFAGQVNICLLMTHMACADTPGAPANADQMRRFADFAARLPSVPRSLANSAAAMFLPEAAGDVLRPGL
VLYGVDPGAGGVPKMQPAIALEARIIQLRHIPAGAGVGYGFDYIADRPLRVATLSAGYADGWPRALSNGGATWFAGHRLP
ILGRVSMDSCMVDVTNLPEGSIRPGDCVELIGPHQSVNDLARQLATTPHEILTSLGRRFTRSYINPPSLHGEEAQS
>Mature_396_residues
MVTEAAAPASHFQIEHTSTWHPSTDEAGRLTIDMGAIAANYRRLRAMHPAARVAAVVKADAYGLDATQIAPMLAGQGARD
FFVAHLAEALVLKPLLPPDAVLFVLNGLAPGSEPLCAEAGILPVLNTPEQARAWYTLAVNKAHPVPAALQVDTGMSRLGL
SEGELNDVLGWPSFAGQVNICLLMTHMACADTPGAPANADQMRRFADFAARLPSVPRSLANSAAAMFLPEAAGDVLRPGL
VLYGVDPGAGGVPKMQPAIALEARIIQLRHIPAGAGVGYGFDYIADRPLRVATLSAGYADGWPRALSNGGATWFAGHRLP
ILGRVSMDSCMVDVTNLPEGSIRPGDCVELIGPHQSVNDLARQLATTPHEILTSLGRRFTRSYINPPSLHGEEAQS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=368, Percent_Identity=31.5217391304348, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787439, Length=355, Percent_Identity=31.2676056338028, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41796; Mature: 41796

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTEAAAPASHFQIEHTSTWHPSTDEAGRLTIDMGAIAANYRRLRAMHPAARVAAVVKAD
CCCCCCCCCHHEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHC
AYGLDATQIAPMLAGQGARDFFVAHLAEALVLKPLLPPDAVLFVLNGLAPGSEPLCAEAG
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCC
ILPVLNTPEQARAWYTLAVNKAHPVPAALQVDTGMSRLGLSEGELNDVLGWPSFAGQVNI
CCCCCCCCHHHCEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCHHHHCCCCCCCCCEEE
CLLMTHMACADTPGAPANADQMRRFADFAARLPSVPRSLANSAAAMFLPEAAGDVLRPGL
EHEEHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCHHHHHHHCCCE
VLYGVDPGAGGVPKMQPAIALEARIIQLRHIPAGAGVGYGFDYIADRPLRVATLSAGYAD
EEEECCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCCHHHHCCCCEEEEEECCCCCC
GWPRALSNGGATWFAGHRLPILGRVSMDSCMVDVTNLPEGSIRPGDCVELIGPHQSVNDL
CCHHHHCCCCCEEEECCCCCEEECCCCCHHEEEECCCCCCCCCCCCHHHHCCCCCCHHHH
ARQLATTPHEILTSLGRRFTRSYINPPSLHGEEAQS
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVTEAAAPASHFQIEHTSTWHPSTDEAGRLTIDMGAIAANYRRLRAMHPAARVAAVVKAD
CCCCCCCCCHHEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCHHHHHHHHHHHC
AYGLDATQIAPMLAGQGARDFFVAHLAEALVLKPLLPPDAVLFVLNGLAPGSEPLCAEAG
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCC
ILPVLNTPEQARAWYTLAVNKAHPVPAALQVDTGMSRLGLSEGELNDVLGWPSFAGQVNI
CCCCCCCCHHHCEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCHHHHCCCCCCCCCEEE
CLLMTHMACADTPGAPANADQMRRFADFAARLPSVPRSLANSAAAMFLPEAAGDVLRPGL
EHEEHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCHHHHHHHCCCE
VLYGVDPGAGGVPKMQPAIALEARIIQLRHIPAGAGVGYGFDYIADRPLRVATLSAGYAD
EEEECCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCCHHHHCCCCEEEEEECCCCCC
GWPRALSNGGATWFAGHRLPILGRVSMDSCMVDVTNLPEGSIRPGDCVELIGPHQSVNDL
CCHHHHCCCCCEEEECCCCCEEECCCCCHHEEEECCCCCCCCCCCCHHHHCCCCCCHHHH
ARQLATTPHEILTSLGRRFTRSYINPPSLHGEEAQS
HHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA