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The map label for this gene is qseD [H]

Identifier: 114799401

GI number: 114799401

Start: 1494075

End: 1494995

Strand: Direct

Name: qseD [H]

Synonym: HNE_1468

Alternate gene names: 114799401

Gene position: 1494075-1494995 (Clockwise)

Preceding gene: 114798594

Following gene: 114797811

Centisome position: 40.33

GC content: 64.06

Gene sequence:

>921_bases
ATGAATGTTGACTGGCTTGAAGATTATCTGGCGTTGATCGAAGCGGGCGGATTTGCGCGCGCAGCCGAGCGAAGGGCGAT
GACCCAGCCGACCTTCAGTCGGCGCATACGTGCGCTGGAGGATTGGGTCGGCGTTACCCTGATCGACCGGGGCACACATA
CGATGCGCCTGACTCCGGCAGGGGAGCGTTTCAAGACGGTTGCCGAGCTGGCGACGCGGCAGCTGCAGCTGGGCCGCGAA
GAGGCGCGCGCGGTCGCAAAGGCGTCGTCGGAGACCCTGCGCTTTGCCGCAACGCATGCGCTTTCGCTTACTTTCTTTCC
AAACTGGCTGCGCCAGCTGGAGAAAGACGAGCCGGCAACGGTGACCGTTGAGCTGACGGCCGATCATATGGTGGCGTGTG
AGCGACTGATGATTGAGGGACGGGCCCAGTTTCTGCTCTGTCACCACCATGAGGCGGCGCCGACGCGTCTTGGCAGGGAT
TTCCGATCGGTACTTCTGGGCGGGGATGTCCTGTTGCCGGTGATATCTCCGCAGCTGGCGGCTGAAACCCCGCCGGAAAA
GGCACCCCAGCTGGCATTGTCACCGGAGTCCGGCATGGGCCGAATTCTTGCCGCCGCCTGGGCGATGACCGGGCGCGAGC
CTCCGTCCATGCCTGCGTTTACGTCCCATCTCGCGAGCGTCCTGACAGCGATGGCGCGGAACGGGCGCGGGGTCGCGTGG
ACGGCGCTGAGCCTGGTGAGCGAGGACATCTCGACCGGAAAGCTGATGCGGGCGGGCACCCCGGAGCAGGATGTGCCGAT
CGAGATCCGGTTATGGCGGCCCGCTACCCGTCAGTCTCCTGCCGCCGAGGCGCTCTGGTCGAAGATTCTGAAAAGCCAGA
AGTCCGCATTGTCTGCCGGGCAGACAACAAATGATCCGTAG

Upstream 100 bases:

>100_bases
CGGCCCGGAACGGCGCCCAGCCGGGCCAGGCCCTCCGACGGGCTGTTCCGGCAAGGCGGTGTGCATCAGGGAACGGCGTG
AAACGGCGGCCGGATTGTTC

Downstream 100 bases:

>100_bases
ACGGTGATCCTTATGTTAGCAGGTCCGGAACGTCCTCTGCCGGAGCGAGCGTTCTGAGCAGGGCCATATCCAACACGGTC
CAGGCGCCTTGCGATTTCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNVDWLEDYLALIEAGGFARAAERRAMTQPTFSRRIRALEDWVGVTLIDRGTHTMRLTPAGERFKTVAELATRQLQLGRE
EARAVAKASSETLRFAATHALSLTFFPNWLRQLEKDEPATVTVELTADHMVACERLMIEGRAQFLLCHHHEAAPTRLGRD
FRSVLLGGDVLLPVISPQLAAETPPEKAPQLALSPESGMGRILAAAWAMTGREPPSMPAFTSHLASVLTAMARNGRGVAW
TALSLVSEDISTGKLMRAGTPEQDVPIEIRLWRPATRQSPAAEALWSKILKSQKSALSAGQTTNDP

Sequences:

>Translated_306_residues
MNVDWLEDYLALIEAGGFARAAERRAMTQPTFSRRIRALEDWVGVTLIDRGTHTMRLTPAGERFKTVAELATRQLQLGRE
EARAVAKASSETLRFAATHALSLTFFPNWLRQLEKDEPATVTVELTADHMVACERLMIEGRAQFLLCHHHEAAPTRLGRD
FRSVLLGGDVLLPVISPQLAAETPPEKAPQLALSPESGMGRILAAAWAMTGREPPSMPAFTSHLASVLTAMARNGRGVAW
TALSLVSEDISTGKLMRAGTPEQDVPIEIRLWRPATRQSPAAEALWSKILKSQKSALSAGQTTNDP
>Mature_306_residues
MNVDWLEDYLALIEAGGFARAAERRAMTQPTFSRRIRALEDWVGVTLIDRGTHTMRLTPAGERFKTVAELATRQLQLGRE
EARAVAKASSETLRFAATHALSLTFFPNWLRQLEKDEPATVTVELTADHMVACERLMIEGRAQFLLCHHHEAAPTRLGRD
FRSVLLGGDVLLPVISPQLAAETPPEKAPQLALSPESGMGRILAAAWAMTGREPPSMPAFTSHLASVLTAMARNGRGVAW
TALSLVSEDISTGKLMRAGTPEQDVPIEIRLWRPATRQSPAAEALWSKILKSQKSALSAGQTTNDP

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=296, Percent_Identity=29.0540540540541, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=35.042735042735, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33506; Mature: 33506

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDWLEDYLALIEAGGFARAAERRAMTQPTFSRRIRALEDWVGVTLIDRGTHTMRLTPA
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCEEEEECCC
GERFKTVAELATRQLQLGREEARAVAKASSETLRFAATHALSLTFFPNWLRQLEKDEPAT
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCE
VTVELTADHMVACERLMIEGRAQFLLCHHHEAAPTRLGRDFRSVLLGGDVLLPVISPQLA
EEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEHHCCCHHH
AETPPEKAPQLALSPESGMGRILAAAWAMTGREPPSMPAFTSHLASVLTAMARNGRGVAW
CCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
TALSLVSEDISTGKLMRAGTPEQDVPIEIRLWRPATRQSPAAEALWSKILKSQKSALSAG
HHHHHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
QTTNDP
CCCCCC
>Mature Secondary Structure
MNVDWLEDYLALIEAGGFARAAERRAMTQPTFSRRIRALEDWVGVTLIDRGTHTMRLTPA
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCEEEEECCC
GERFKTVAELATRQLQLGREEARAVAKASSETLRFAATHALSLTFFPNWLRQLEKDEPAT
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCE
VTVELTADHMVACERLMIEGRAQFLLCHHHEAAPTRLGRDFRSVLLGGDVLLPVISPQLA
EEEEECCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEHHCCCHHH
AETPPEKAPQLALSPESGMGRILAAAWAMTGREPPSMPAFTSHLASVLTAMARNGRGVAW
CCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHH
TALSLVSEDISTGKLMRAGTPEQDVPIEIRLWRPATRQSPAAEALWSKILKSQKSALSAG
HHHHHHHHHHCCCCEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
QTTNDP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]