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The map label for this gene is rbsK [H]

Identifier: 114799341

GI number: 114799341

Start: 192246

End: 193088

Strand: Reverse

Name: rbsK [H]

Synonym: HNE_0207

Alternate gene names: 114799341

Gene position: 193088-192246 (Counterclockwise)

Preceding gene: 114798081

Following gene: 114800272

Centisome position: 5.21

GC content: 68.09

Gene sequence:

>843_bases
ATGATCACCGTCGTCGGCTCGGTCAATCTCGATTTTGTCGCCAGCGGAAAATCCCTCCCCCATGCGGGGGAAACCGTCAC
CGGCGCCCGCCTCGCGCGCCATCCCGGCGGCAAGGGCGCCAACCAGGCGCTCGCCGCCCGCCGCCTCGGCGCAGATGTGC
GCCTCGTCGCGGCGGTCGGCAATGACGACATGGCCGAAGAGGCGCTCAAGCTGCTGCGCCATGGCGGCGTGGACCTCTCG
GCCACGCAGTACATCAATGGAGAGACAACCGGCGTCGCCCTGATTGCGGTCTCCGCCGAAGGCGAAAACCAGATCATCGT
CTGTCCCGGCGCCAATGATGCGCTTGATCCGGGCGATGTCGAAGGCGCCACCATCGAACATATGATGGGCGTGCTCGAAG
TGCCTGCCGCCACGCTGCTGGCCGCCGCCGAGCGCGCCACCGGCTTTGTCGCGCTGAACCTCGCCCCGGCCATGAAAATC
CCGGAAGCGCTGATCGCGCGCGCCTCCCTCCTCATCGTCAATGAAACCGAAGCCGCCTTCTATGGCCCCGCGCTGCACGG
CCCCGGCCGCTACGTCGCCATTTCCCTCGGCGCAGCCGGCGCCCAGCTCTGGAAAGACGGCGAAATGATCGCCTCTGCCG
CGCCCCCCGATGTAAAGGTCATCGACACGACCGGCGCCGGCGACACCTTCAGCGCCGCCCTCACGGTCAGCCTCATCAAG
GGCAAATCCCCCGAAGACGCCCTCACCTACGCCGTCACCGCCGGCTCCCTCGCCTGCACCAAACCCGGCGCCCAACCCAG
CCTGCCCCGCCGCGCCGAAGTCGAGGCGCTGCTGAAATCCTGA

Upstream 100 bases:

>100_bases
CGAAAGTCCGCCCCATGAAGACGGGCCCCCATCGCTGGGTCACAAAAGCGAATGCCGATGCCTTCTTTGCACGGATCGAA
GACATATTGAGGATCGCGCC

Downstream 100 bases:

>100_bases
TCATCCGCACAGGGATTAAGATCACTTACCCCTCTCCCTCTGGGAGAGGAGGGGCCCATCGCGCAGCGATGGGAGGTGAG
GGCTCGGGCAACGAGGATAA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MITVVGSVNLDFVASGKSLPHAGETVTGARLARHPGGKGANQALAARRLGADVRLVAAVGNDDMAEEALKLLRHGGVDLS
ATQYINGETTGVALIAVSAEGENQIIVCPGANDALDPGDVEGATIEHMMGVLEVPAATLLAAAERATGFVALNLAPAMKI
PEALIARASLLIVNETEAAFYGPALHGPGRYVAISLGAAGAQLWKDGEMIASAAPPDVKVIDTTGAGDTFSAALTVSLIK
GKSPEDALTYAVTAGSLACTKPGAQPSLPRRAEVEALLKS

Sequences:

>Translated_280_residues
MITVVGSVNLDFVASGKSLPHAGETVTGARLARHPGGKGANQALAARRLGADVRLVAAVGNDDMAEEALKLLRHGGVDLS
ATQYINGETTGVALIAVSAEGENQIIVCPGANDALDPGDVEGATIEHMMGVLEVPAATLLAAAERATGFVALNLAPAMKI
PEALIARASLLIVNETEAAFYGPALHGPGRYVAISLGAAGAQLWKDGEMIASAAPPDVKVIDTTGAGDTFSAALTVSLIK
GKSPEDALTYAVTAGSLACTKPGAQPSLPRRAEVEALLKS
>Mature_280_residues
MITVVGSVNLDFVASGKSLPHAGETVTGARLARHPGGKGANQALAARRLGADVRLVAAVGNDDMAEEALKLLRHGGVDLS
ATQYINGETTGVALIAVSAEGENQIIVCPGANDALDPGDVEGATIEHMMGVLEVPAATLLAAAERATGFVALNLAPAMKI
PEALIARASLLIVNETEAAFYGPALHGPGRYVAISLGAAGAQLWKDGEMIASAAPPDVKVIDTTGAGDTFSAALTVSLIK
GKSPEDALTYAVTAGSLACTKPGAQPSLPRRAEVEALLKS

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=31.0810810810811, Blast_Score=102, Evalue=4e-22,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=39.202657807309, Blast_Score=157, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=30.6666666666667, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319884, Length=328, Percent_Identity=28.9634146341463, Blast_Score=105, Evalue=7e-24,
Organism=Drosophila melanogaster, GI20128807, Length=298, Percent_Identity=35.5704697986577, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=29.2763157894737, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 28318; Mature: 28318

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVVGSVNLDFVASGKSLPHAGETVTGARLARHPGGKGANQALAARRLGADVRLVAAVG
CEEEEECCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEEC
NDDMAEEALKLLRHGGVDLSATQYINGETTGVALIAVSAEGENQIIVCPGANDALDPGDV
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCC
EGATIEHMMGVLEVPAATLLAAAERATGFVALNLAPAMKIPEALIARASLLIVNETEAAF
CCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCEEEEEEECCCCEE
YGPALHGPGRYVAISLGAAGAQLWKDGEMIASAAPPDVKVIDTTGAGDTFSAALTVSLIK
ECCCCCCCCCEEEEEECCCCHHHHCCCCEEECCCCCCEEEEECCCCCCCEEHEEEEEEEC
GKSPEDALTYAVTAGSLACTKPGAQPSLPRRAEVEALLKS
CCCCCHHEEEEEECCCEEECCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MITVVGSVNLDFVASGKSLPHAGETVTGARLARHPGGKGANQALAARRLGADVRLVAAVG
CEEEEECCCEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEEC
NDDMAEEALKLLRHGGVDLSATQYINGETTGVALIAVSAEGENQIIVCPGANDALDPGDV
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCC
EGATIEHMMGVLEVPAATLLAAAERATGFVALNLAPAMKIPEALIARASLLIVNETEAAF
CCCHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCEEEEEEECCCCEE
YGPALHGPGRYVAISLGAAGAQLWKDGEMIASAAPPDVKVIDTTGAGDTFSAALTVSLIK
ECCCCCCCCCEEEEEECCCCHHHHCCCCEEECCCCCCEEEEECCCCCCCEEHEEEEEEEC
GKSPEDALTYAVTAGSLACTKPGAQPSLPRRAEVEALLKS
CCCCCHHEEEEEECCCEEECCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]