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The map label for this gene is yhcK [H]

Identifier: 114799302

GI number: 114799302

Start: 2712150

End: 2713379

Strand: Direct

Name: yhcK [H]

Synonym: HNE_2558

Alternate gene names: 114799302

Gene position: 2712150-2713379 (Clockwise)

Preceding gene: 114800258

Following gene: 114798360

Centisome position: 73.2

GC content: 64.63

Gene sequence:

>1230_bases
ATGAGCGCCCAGTTTTTCATCATGCTTCTGAATCCCGGCATCGGCGCCCTTCTGGCGGCGGCGTTCTGTATGCTGTGGCT
CAACCAGCGCGACAAATCCTACGTCATGCTGGCCAGCGCCGGCTATGCGATGACTGCCCTGGGCTTTTTCATTCAGGATG
TGGCGTTCCAGTATATCGCCGCGCCGCTGCCGGGACGCGCCGAGCGCATCCTCTCCAATATCGGCTTCCTGTCGGCAGGC
TGGCTGCTGACCATGGCGGTGCTGGGCCGGTTCGGCATTCGGCCATCCTATCCCGTCCTTATCGTCGCCAGCATCGTTGC
GCTGGTGGGGCATGCCTGGTTCCTGCTGGTTGATCCCAGCGTTGCGGGCCGGGTGCTGGTCGTCAATGCCGCCCTGGGCG
CCATGATGCTGATGATCGTGGTCAAGGTTGCGCCGGTGCGCAGCAAGCACCTGACAGACCGGTTGCTCATGGGTGTCGCC
GCTCTGGCGGCGGCCAACTACATCCTCCGCCCGGTCGTCATCCTCTGGCTTACCGGCGGCATCGGCAGCAGCAACGACTT
CCAGCACTCCCTCTACTGGACCACCGTTCAGTTCACCCAGCCACTGATCTCGGTCGCTTTCGCGCTCACCCTGATGGTCG
CCATTGCCATCGACCTGATCGATCAGCTCCGCCACGAGGCGCGCGCCGACAAGCTCTCCGGTCTGCTCAACCGCGGCGGC
TTCGAAGCGGCCGCCGACGCGCTGCTCAAGCGCCACAAGCCCGGTCACAACTTGCCGGTCTGCCTCATCATCGCCGATCT
CGACCATTTCAAGCAGATCAACGACACCTTCGGCCATTCGGTCGGCGACGCGGTGATCGGCCTCTTTGGCCGCCATGTCG
CGGCGATGACGTCAGAAGAGATGATTGCCGGCCGTATCGGCGGCGAAGAGTTCGCCGTCCTCCTGCCCGGCCATGAGATC
CAAGCGGCGCGCCTGTTCGCCGAATCCCTGCGCGCCTGCCCGTGGGACTACTGGTCGGGCATGCTCCCTGGTGGCCTGGC
CCCCAGCGTCAGTATCGGCGTCGCCGGCGGCTGGCCGGGCGTTGACCTCTATTCGCTCATGAACAACGCCGATGAAGCCC
TCTATGACGCCAAAAGAGCGGGCCGCGACCAGGTTCGCCTGTTTGGGGTCAAGCCGCCGCCTGTCGCTTCGGTGACCGCC
GCGCTCAGCCGCATCCGCGTCAAATCCTGA

Upstream 100 bases:

>100_bases
CCGCGCAAATCGATCAAATTTGCCGCTTCGGTTAAAGGTCACTTTAGCCCAATCCTGCGCAATAGGCCGTTTGGACAACA
AGGACTGCTTGCCCAAGCCC

Downstream 100 bases:

>100_bases
CGTTCCGGGGCGCCAAACCGCCCTTTTCCTGCTATATAAAGAATAACCTGCATATCCCCCCACATTTCCCGCAATCGGCG
TGAAGTTGGGGTTTGACAGC

Product: putative diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSAQFFIMLLNPGIGALLAAAFCMLWLNQRDKSYVMLASAGYAMTALGFFIQDVAFQYIAAPLPGRAERILSNIGFLSAG
WLLTMAVLGRFGIRPSYPVLIVASIVALVGHAWFLLVDPSVAGRVLVVNAALGAMMLMIVVKVAPVRSKHLTDRLLMGVA
ALAAANYILRPVVILWLTGGIGSSNDFQHSLYWTTVQFTQPLISVAFALTLMVAIAIDLIDQLRHEARADKLSGLLNRGG
FEAAADALLKRHKPGHNLPVCLIIADLDHFKQINDTFGHSVGDAVIGLFGRHVAAMTSEEMIAGRIGGEEFAVLLPGHEI
QAARLFAESLRACPWDYWSGMLPGGLAPSVSIGVAGGWPGVDLYSLMNNADEALYDAKRAGRDQVRLFGVKPPPVASVTA
ALSRIRVKS

Sequences:

>Translated_409_residues
MSAQFFIMLLNPGIGALLAAAFCMLWLNQRDKSYVMLASAGYAMTALGFFIQDVAFQYIAAPLPGRAERILSNIGFLSAG
WLLTMAVLGRFGIRPSYPVLIVASIVALVGHAWFLLVDPSVAGRVLVVNAALGAMMLMIVVKVAPVRSKHLTDRLLMGVA
ALAAANYILRPVVILWLTGGIGSSNDFQHSLYWTTVQFTQPLISVAFALTLMVAIAIDLIDQLRHEARADKLSGLLNRGG
FEAAADALLKRHKPGHNLPVCLIIADLDHFKQINDTFGHSVGDAVIGLFGRHVAAMTSEEMIAGRIGGEEFAVLLPGHEI
QAARLFAESLRACPWDYWSGMLPGGLAPSVSIGVAGGWPGVDLYSLMNNADEALYDAKRAGRDQVRLFGVKPPPVASVTA
ALSRIRVKS
>Mature_408_residues
SAQFFIMLLNPGIGALLAAAFCMLWLNQRDKSYVMLASAGYAMTALGFFIQDVAFQYIAAPLPGRAERILSNIGFLSAGW
LLTMAVLGRFGIRPSYPVLIVASIVALVGHAWFLLVDPSVAGRVLVVNAALGAMMLMIVVKVAPVRSKHLTDRLLMGVAA
LAAANYILRPVVILWLTGGIGSSNDFQHSLYWTTVQFTQPLISVAFALTLMVAIAIDLIDQLRHEARADKLSGLLNRGGF
EAAADALLKRHKPGHNLPVCLIIADLDHFKQINDTFGHSVGDAVIGLFGRHVAAMTSEEMIAGRIGGEEFAVLLPGHEIQ
AARLFAESLRACPWDYWSGMLPGGLAPSVSIGVAGGWPGVDLYSLMNNADEALYDAKRAGRDQVRLFGVKPPPVASVTAA
LSRIRVKS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=32.0388349514563, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082007, Length=197, Percent_Identity=36.5482233502538, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787802, Length=186, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081881, Length=295, Percent_Identity=30.8474576271186, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788381, Length=193, Percent_Identity=30.0518134715026, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=33.9393939393939, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693134, Length=193, Percent_Identity=31.6062176165803, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=29.559748427673, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=29.6511627906977, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081974, Length=197, Percent_Identity=27.4111675126904, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 43899; Mature: 43768

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQFFIMLLNPGIGALLAAAFCMLWLNQRDKSYVMLASAGYAMTALGFFIQDVAFQYIA
CCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
APLPGRAERILSNIGFLSAGWLLTMAVLGRFGIRPSYPVLIVASIVALVGHAWFLLVDPS
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
VAGRVLVVNAALGAMMLMIVVKVAPVRSKHLTDRLLMGVAALAAANYILRPVVILWLTGG
CCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGSSNDFQHSLYWTTVQFTQPLISVAFALTLMVAIAIDLIDQLRHEARADKLSGLLNRGG
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FEAAADALLKRHKPGHNLPVCLIIADLDHFKQINDTFGHSVGDAVIGLFGRHVAAMTSEE
HHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MIAGRIGGEEFAVLLPGHEIQAARLFAESLRACPWDYWSGMLPGGLAPSVSIGVAGGWPG
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEECCCCCC
VDLYSLMNNADEALYDAKRAGRDQVRLFGVKPPPVASVTAALSRIRVKS
HHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAQFFIMLLNPGIGALLAAAFCMLWLNQRDKSYVMLASAGYAMTALGFFIQDVAFQYIA
CCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
APLPGRAERILSNIGFLSAGWLLTMAVLGRFGIRPSYPVLIVASIVALVGHAWFLLVDPS
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCC
VAGRVLVVNAALGAMMLMIVVKVAPVRSKHLTDRLLMGVAALAAANYILRPVVILWLTGG
CCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGSSNDFQHSLYWTTVQFTQPLISVAFALTLMVAIAIDLIDQLRHEARADKLSGLLNRGG
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FEAAADALLKRHKPGHNLPVCLIIADLDHFKQINDTFGHSVGDAVIGLFGRHVAAMTSEE
HHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
MIAGRIGGEEFAVLLPGHEIQAARLFAESLRACPWDYWSGMLPGGLAPSVSIGVAGGWPG
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEECCCCCC
VDLYSLMNNADEALYDAKRAGRDQVRLFGVKPPPVASVTAALSRIRVKS
HHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]