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The map label for this gene is 114799222

Identifier: 114799222

GI number: 114799222

Start: 1924314

End: 1925210

Strand: Direct

Name: 114799222

Synonym: HNE_1861

Alternate gene names: NA

Gene position: 1924314-1925210 (Clockwise)

Preceding gene: 114797386

Following gene: 114799982

Centisome position: 51.94

GC content: 55.63

Gene sequence:

>897_bases
TTGATCGTCACATCCCTGCACTATTCAGGTCACAAGGATGGTGCCGCAATGATGAAGACAACAGTGAGCGAGGAATGGCT
AACCTACACTTGGGTTCGCCTGCGGTCAGGCGTGGAACCTCATGAGGTAAAGCGCCAGCTGATACAAAACGGATTTGATG
ACCAGGCGATCCGTTCACTCATGCGGGACGCATATAATGGCCGCCGCCCGATTTCAGATGTCGATCACGCAGCGCTGGCC
AGGGCGCCCCTCACGCTTCGGGCAAAGTCGCACCCCCAGCTCCGCCGCATCCCCGCCCCAAAGGCCCAACTTTATGTCTG
GCCAAATTTCCTGGCCCCGGAAACCTGCGACGCCTTGATCGCTCTCACGGATGAGCGCCTGCGGGCGTCCACAACTACCG
ACGCTTTTGCAGACCCGAAGATCCGCACATCCCGCTCCTCAGACATCGGCACGATGGGGCATAATCTGGTCATGCAACTC
GACGAACTGATCGCTGAAGCACTTGGCATTCACTGGTCCTATTCAGATGCCACACAGACACAGCGTTATGACGTCAACCA
GGAATACAAAGCCCACTACGACTACTTCACCCCCGGCACGCGGGATTATCAGGTTCATTGCCAGTTCACCGGCCAGCGCA
CCTGGACCTTCATGATCTACCTGAATGATGTCGAGGAAGGCGGCGGCACGCGTTTCCGGCGGCTAGAGAAAACGATCATG
CCTGAAAAGGGAAAGGCCGTAATCTGGAACAATCTGAACCCGGACGGCAGCGTAAATCCGTATACGATCCATCATGGCAT
GAAAGTTCGATCCGGCGCTAAATATGTGATCACGAAATGGTTCCGCGAACGTGGCTGGGGAGAGATGTTTCCTGAGGACT
ACTCCAGAATTTCGTAA

Upstream 100 bases:

>100_bases
TACAGTTTTGCGTCAAGGACATCCACGTATTTGTATATTCCGTGTAGGACCAGTTTTATTCCGTGCACGTCTTTGCTTCC
CGCTTTGATTCCGGCGTCAT

Downstream 100 bases:

>100_bases
TGTTGCCAAGGGGTCACACACGCACCGGCGAACGCTGGCTTCACATAAGCGTCATCTAAACTTCCCGTAAGTGTTGCAAT
CAAATCTTAAGGGTTCGCGC

Product: 2OG-Fe(II) oxygenase family oxidoreductase

Products: NA

Alternate protein names: 2OG-Fe(II) Oxygenase; Prolyl 4-Hydroxylase Alpha Subunit; Oxidoreductase 2OG-Fe(II) Oxygenase Family; Oxygenase; Procollagen-Proline 2-Oxoglutarate-4-Dioxygenase; Response Regulator Receiver Domain-Containing Protein; 2OG-Fe(II) Oxygenase Family Oxidoreductase; Prolyl 4-Hydroxylase Subunit Alpha; 2OG-Fe(II) Oxygenase Superfamily Protein; 2OG-Fe(II) Oxygenase Family Protein; Procollagen-Proline 2-Oxoglutarate-4- Dioxygenase; Prolyl 4-Hydroxylase

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MIVTSLHYSGHKDGAAMMKTTVSEEWLTYTWVRLRSGVEPHEVKRQLIQNGFDDQAIRSLMRDAYNGRRPISDVDHAALA
RAPLTLRAKSHPQLRRIPAPKAQLYVWPNFLAPETCDALIALTDERLRASTTTDAFADPKIRTSRSSDIGTMGHNLVMQL
DELIAEALGIHWSYSDATQTQRYDVNQEYKAHYDYFTPGTRDYQVHCQFTGQRTWTFMIYLNDVEEGGGTRFRRLEKTIM
PEKGKAVIWNNLNPDGSVNPYTIHHGMKVRSGAKYVITKWFRERGWGEMFPEDYSRIS

Sequences:

>Translated_298_residues
MIVTSLHYSGHKDGAAMMKTTVSEEWLTYTWVRLRSGVEPHEVKRQLIQNGFDDQAIRSLMRDAYNGRRPISDVDHAALA
RAPLTLRAKSHPQLRRIPAPKAQLYVWPNFLAPETCDALIALTDERLRASTTTDAFADPKIRTSRSSDIGTMGHNLVMQL
DELIAEALGIHWSYSDATQTQRYDVNQEYKAHYDYFTPGTRDYQVHCQFTGQRTWTFMIYLNDVEEGGGTRFRRLEKTIM
PEKGKAVIWNNLNPDGSVNPYTIHHGMKVRSGAKYVITKWFRERGWGEMFPEDYSRIS
>Mature_298_residues
MIVTSLHYSGHKDGAAMMKTTVSEEWLTYTWVRLRSGVEPHEVKRQLIQNGFDDQAIRSLMRDAYNGRRPISDVDHAALA
RAPLTLRAKSHPQLRRIPAPKAQLYVWPNFLAPETCDALIALTDERLRASTTTDAFADPKIRTSRSSDIGTMGHNLVMQL
DELIAEALGIHWSYSDATQTQRYDVNQEYKAHYDYFTPGTRDYQVHCQFTGQRTWTFMIYLNDVEEGGGTRFRRLEKTIM
PEKGKAVIWNNLNPDGSVNPYTIHHGMKVRSGAKYVITKWFRERGWGEMFPEDYSRIS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4758868, Length=144, Percent_Identity=35.4166666666667, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI217272863, Length=144, Percent_Identity=35.4166666666667, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI63252893, Length=144, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI63252891, Length=144, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI217272861, Length=144, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI63252886, Length=144, Percent_Identity=31.25, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI217272849, Length=168, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI63252888, Length=168, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI33589818, Length=120, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17552840, Length=266, Percent_Identity=24.4360902255639, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193209070, Length=175, Percent_Identity=27.4285714285714, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193209068, Length=165, Percent_Identity=27.8787878787879, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17541712, Length=184, Percent_Identity=23.9130434782609, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24651477, Length=185, Percent_Identity=28.6486486486486, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI78706702, Length=146, Percent_Identity=36.3013698630137, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI116008434, Length=204, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281361323, Length=155, Percent_Identity=34.1935483870968, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116008537, Length=155, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116008130, Length=155, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24651418, Length=156, Percent_Identity=31.4102564102564, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24651407, Length=156, Percent_Identity=29.4871794871795, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221460681, Length=206, Percent_Identity=27.1844660194175, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21358233, Length=208, Percent_Identity=29.3269230769231, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24651430, Length=169, Percent_Identity=28.4023668639053, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24666354, Length=129, Percent_Identity=30.2325581395349, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI116008432, Length=129, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116008128, Length=129, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24651416, Length=119, Percent_Identity=33.6134453781513, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24651420, Length=179, Percent_Identity=25.1396648044693, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21358309, Length=119, Percent_Identity=33.6134453781513, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651424, Length=142, Percent_Identity=27.4647887323944, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512818, Length=137, Percent_Identity=25.5474452554745, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281362877, Length=153, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34305; Mature: 34305

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVTSLHYSGHKDGAAMMKTTVSEEWLTYTWVRLRSGVEPHEVKRQLIQNGFDDQAIRSL
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHH
MRDAYNGRRPISDVDHAALARAPLTLRAKSHPQLRRIPAPKAQLYVWPNFLAPETCDALI
HHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCHHHCCCCCCCEEEECCCCCCCHHHHHHE
ALTDERLRASTTTDAFADPKIRTSRSSDIGTMGHNLVMQLDELIAEALGIHWSYSDATQT
EECHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
QRYDVNQEYKAHYDYFTPGTRDYQVHCQFTGQRTWTFMIYLNDVEEGGGTRFRRLEKTIM
HHCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEEEEEECCCCCCHHHHHHHHHHC
PEKGKAVIWNNLNPDGSVNPYTIHHGMKVRSGAKYVITKWFRERGWGEMFPEDYSRIS
CCCCCEEEECCCCCCCCCCCEEEECCEEECCCCHHHHHHHHHHCCCCCCCCHHHHHCC
>Mature Secondary Structure
MIVTSLHYSGHKDGAAMMKTTVSEEWLTYTWVRLRSGVEPHEVKRQLIQNGFDDQAIRSL
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHH
MRDAYNGRRPISDVDHAALARAPLTLRAKSHPQLRRIPAPKAQLYVWPNFLAPETCDALI
HHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCHHHCCCCCCCEEEECCCCCCCHHHHHHE
ALTDERLRASTTTDAFADPKIRTSRSSDIGTMGHNLVMQLDELIAEALGIHWSYSDATQT
EECHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
QRYDVNQEYKAHYDYFTPGTRDYQVHCQFTGQRTWTFMIYLNDVEEGGGTRFRRLEKTIM
HHCCCCCHHHHCCCCCCCCCCCEEEEEEEECCCEEEEEEEEEECCCCCCHHHHHHHHHHC
PEKGKAVIWNNLNPDGSVNPYTIHHGMKVRSGAKYVITKWFRERGWGEMFPEDYSRIS
CCCCCEEEECCCCCCCCCCCEEEECCEEECCCCHHHHHHHHHHCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA