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The map label for this gene is mmgC [H]

Identifier: 114799144

GI number: 114799144

Start: 2552632

End: 2553888

Strand: Reverse

Name: mmgC [H]

Synonym: HNE_2441

Alternate gene names: 114799144

Gene position: 2553888-2552632 (Counterclockwise)

Preceding gene: 114799270

Following gene: 114798496

Centisome position: 68.93

GC content: 61.89

Gene sequence:

>1257_bases
ATGGATTTCAAAGATACACCTGAAGAAGCCGCCTTCCGCGCTGAAGTCCGCGCCTGGATCGACGCTAACGCCCCCAAGCA
TCTGGAAGGCGAACTGAAGCGCGCCAGCTTCGGCTCAAACGGCATTGCCAGCGAAGATCCCATCGCGGCTGGCAAAGCCT
GGCAGAAGAAAAAGGCCGAGGCCGGCTGGGCCTGCCTTCACTGGCCAAAGGAATATGGTGGCGGCGCCCGCACGCCGATC
GAGCGTGTGATCTGGGGGCAGGAAGAAGGTCCGTATGCGGCCCTCACGGGCGTCTTCACCATTGGTCACGGCATGTGCGG
CCCCACCGTCATGTCCTGGGCCAGCGAAGAACATAAGCGCGAACTTCTGCCCCCGCTCGCCAGCGGTGAAACTGTCTGGT
GCCAGCTGTTTTCGGAACCCGCGAGCGGCTCTGACCTTGCCGGTCTGCGCACGCGCGCCGTCAAGGCAGATGACGGTTCG
GGCGACTGGATCATCAATGGCCAGAAAATCTGGACCAGCGGCGCTCAGTATTCTGATTGGGGCCTCCTGATCACCCGCAC
CAACCCCGATGTGCCAAAGCACAAGGGCCTCACCATGTTCTTCCTGAACATGAAGAGCCCCGGCGTGGAAGTGCGCCCGA
TTAAACAGGCCAATGGCCAGTCCAGCTTCAACGAAGTCTATTTCACCGACGTCCGTATCCCCGACTCCCAGCGCCTCGGC
GAAGTGGGGCAGGGCTGGGAAGTCTCGCTCACCACCCTGATGAACGAGCGCCTCTCCATCGGTTCGGGCATGTCCACCGG
CTTTCCGGAACTCTTCCGCTTCTGCATGGAAGCGGAAATCGACGGCGCGCCTGCTGTCGATGACTCCGGTGTGCGGTCAA
AGCTCGCCCAGTTCGCGGTCAAGCAGAGTGGCCTGAAATATACCGGCATGCGCGCGATCTCCGCGCTGTCAAAAGGCGAA
ACACCCGGCCCTGAAAACTCCATCGGCAAGCTCGTTGCTGGCGCCGCCATGCAGGAGCTCTCCATGTTCGCCCTCGATCT
TCAGGGCGAGGCAGGCGTTCTCTGGAACGAGGACAGCCCCCAGCAAGGCCGCTTCCAGGCCATGCTGATGCGTTCGCCGG
CGACCCGTATTGAAGGCGGTTCAGACGAAATCCTGCGCAACATCATTGGCGAGCGCGTGCTCGGCCTGCCGGGCGACATC
CGCGTCGACAAGAATGTGGCCTTCAAGGATATCCCGACCAGCGGCCGCAAGAACTGA

Upstream 100 bases:

>100_bases
GGCCGTGGCCCTCGGGTCGCTGTCGAGCTGGGAGAGCCAGCTGATTGAACGCATGAGCGCAGGCAACGCCGAGCAGGCCG
CGTAAAGGGAGGAATGAGAC

Downstream 100 bases:

>100_bases
TACCGCTCTGAAACGCCCGGTTGCTGCCTCGCGGCAATCGGGCGCTCAGCTTTTGCTGAAATCTGATTCCAGCAACTTCA
CGGCAATCTGCCGGGCCCGT

Product: acyl-CoA dehydrogenase family protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MDFKDTPEEAAFRAEVRAWIDANAPKHLEGELKRASFGSNGIASEDPIAAGKAWQKKKAEAGWACLHWPKEYGGGARTPI
ERVIWGQEEGPYAALTGVFTIGHGMCGPTVMSWASEEHKRELLPPLASGETVWCQLFSEPASGSDLAGLRTRAVKADDGS
GDWIINGQKIWTSGAQYSDWGLLITRTNPDVPKHKGLTMFFLNMKSPGVEVRPIKQANGQSSFNEVYFTDVRIPDSQRLG
EVGQGWEVSLTTLMNERLSIGSGMSTGFPELFRFCMEAEIDGAPAVDDSGVRSKLAQFAVKQSGLKYTGMRAISALSKGE
TPGPENSIGKLVAGAAMQELSMFALDLQGEAGVLWNEDSPQQGRFQAMLMRSPATRIEGGSDEILRNIIGERVLGLPGDI
RVDKNVAFKDIPTSGRKN

Sequences:

>Translated_418_residues
MDFKDTPEEAAFRAEVRAWIDANAPKHLEGELKRASFGSNGIASEDPIAAGKAWQKKKAEAGWACLHWPKEYGGGARTPI
ERVIWGQEEGPYAALTGVFTIGHGMCGPTVMSWASEEHKRELLPPLASGETVWCQLFSEPASGSDLAGLRTRAVKADDGS
GDWIINGQKIWTSGAQYSDWGLLITRTNPDVPKHKGLTMFFLNMKSPGVEVRPIKQANGQSSFNEVYFTDVRIPDSQRLG
EVGQGWEVSLTTLMNERLSIGSGMSTGFPELFRFCMEAEIDGAPAVDDSGVRSKLAQFAVKQSGLKYTGMRAISALSKGE
TPGPENSIGKLVAGAAMQELSMFALDLQGEAGVLWNEDSPQQGRFQAMLMRSPATRIEGGSDEILRNIIGERVLGLPGDI
RVDKNVAFKDIPTSGRKN
>Mature_418_residues
MDFKDTPEEAAFRAEVRAWIDANAPKHLEGELKRASFGSNGIASEDPIAAGKAWQKKKAEAGWACLHWPKEYGGGARTPI
ERVIWGQEEGPYAALTGVFTIGHGMCGPTVMSWASEEHKRELLPPLASGETVWCQLFSEPASGSDLAGLRTRAVKADDGS
GDWIINGQKIWTSGAQYSDWGLLITRTNPDVPKHKGLTMFFLNMKSPGVEVRPIKQANGQSSFNEVYFTDVRIPDSQRLG
EVGQGWEVSLTTLMNERLSIGSGMSTGFPELFRFCMEAEIDGAPAVDDSGVRSKLAQFAVKQSGLKYTGMRAISALSKGE
TPGPENSIGKLVAGAAMQELSMFALDLQGEAGVLWNEDSPQQGRFQAMLMRSPATRIEGGSDEILRNIIGERVLGLPGDI
RVDKNVAFKDIPTSGRKN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=348, Percent_Identity=25, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI187960098, Length=348, Percent_Identity=25, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4501857, Length=403, Percent_Identity=23.8213399503722, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4557233, Length=347, Percent_Identity=26.5129682997118, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501859, Length=331, Percent_Identity=25.9818731117825, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7656849, Length=347, Percent_Identity=25.3602305475504, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI21361497, Length=365, Percent_Identity=27.1232876712329, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557235, Length=259, Percent_Identity=29.3436293436293, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI76496475, Length=259, Percent_Identity=29.3436293436293, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226958412, Length=199, Percent_Identity=28.1407035175879, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=23.6363636363636, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI38505218, Length=145, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081958, Length=402, Percent_Identity=25.1243781094527, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1786223, Length=404, Percent_Identity=23.019801980198, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=409, Percent_Identity=25.1833740831296, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=336, Percent_Identity=26.1904761904762, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=341, Percent_Identity=25.5131964809384, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=314, Percent_Identity=26.7515923566879, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=342, Percent_Identity=24.8538011695906, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=343, Percent_Identity=26.530612244898, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=245, Percent_Identity=27.7551020408163, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=291, Percent_Identity=25.7731958762887, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=245, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=202, Percent_Identity=27.2277227722772, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=356, Percent_Identity=23.5955056179775, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=236, Percent_Identity=25.8474576271186, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=229, Percent_Identity=26.2008733624454, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24660351, Length=344, Percent_Identity=25.5813953488372, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281363737, Length=376, Percent_Identity=25.2659574468085, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356377, Length=346, Percent_Identity=23.4104046242775, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24666513, Length=314, Percent_Identity=23.5668789808917, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646207, Length=351, Percent_Identity=24.5014245014245, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355753, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45365; Mature: 45365

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKDTPEEAAFRAEVRAWIDANAPKHLEGELKRASFGSNGIASEDPIAAGKAWQKKKAE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHC
AGWACLHWPKEYGGGARTPIERVIWGQEEGPYAALTGVFTIGHGMCGPTVMSWASEEHKR
CCEEEEECCHHHCCCCCCCHHHHHCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHH
ELLPPLASGETVWCQLFSEPASGSDLAGLRTRAVKADDGSGDWIINGQKIWTSGAQYSDW
HHCCCCCCCCEEEEEEECCCCCCCCCCCHHHEEEECCCCCCCEEECCCEEEECCCCCCCC
GLLITRTNPDVPKHKGLTMFFLNMKSPGVEVRPIKQANGQSSFNEVYFTDVRIPDSQRLG
EEEEECCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEEEEEEECCCHHHHH
EVGQGWEVSLTTLMNERLSIGSGMSTGFPELFRFCMEAEIDGAPAVDDSGVRSKLAQFAV
HCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
KQSGLKYTGMRAISALSKGETPGPENSIGKLVAGAAMQELSMFALDLQGEAGVLWNEDSP
HHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCC
QQGRFQAMLMRSPATRIEGGSDEILRNIIGERVLGLPGDIRVDKNVAFKDIPTSGRKN
CCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEECCCCCCCCC
>Mature Secondary Structure
MDFKDTPEEAAFRAEVRAWIDANAPKHLEGELKRASFGSNGIASEDPIAAGKAWQKKKAE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHC
AGWACLHWPKEYGGGARTPIERVIWGQEEGPYAALTGVFTIGHGMCGPTVMSWASEEHKR
CCEEEEECCHHHCCCCCCCHHHHHCCCCCCCEEEHHHHHHHCCCCCCHHHHHHHHHHHHH
ELLPPLASGETVWCQLFSEPASGSDLAGLRTRAVKADDGSGDWIINGQKIWTSGAQYSDW
HHCCCCCCCCEEEEEEECCCCCCCCCCCHHHEEEECCCCCCCEEECCCEEEECCCCCCCC
GLLITRTNPDVPKHKGLTMFFLNMKSPGVEVRPIKQANGQSSFNEVYFTDVRIPDSQRLG
EEEEECCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCEEEEEEEECCCHHHHH
EVGQGWEVSLTTLMNERLSIGSGMSTGFPELFRFCMEAEIDGAPAVDDSGVRSKLAQFAV
HCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
KQSGLKYTGMRAISALSKGETPGPENSIGKLVAGAAMQELSMFALDLQGEAGVLWNEDSP
HHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCC
QQGRFQAMLMRSPATRIEGGSDEILRNIIGERVLGLPGDIRVDKNVAFKDIPTSGRKN
CCCHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEECCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]