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The map label for this gene is aglA [H]

Identifier: 114798942

GI number: 114798942

Start: 2641198

End: 2642781

Strand: Direct

Name: aglA [H]

Synonym: HNE_2506

Alternate gene names: 114798942

Gene position: 2641198-2642781 (Clockwise)

Preceding gene: 114799631

Following gene: 114797240

Centisome position: 71.29

GC content: 59.03

Gene sequence:

>1584_bases
ATGAGCGAACCCTGGTGGCACGGCGCGACGATTTATCAGATCTATCCCCGCAGCTTTAGTGATTCCAATGGCGACGGGAT
CGGAGACCTTCCGGGAATAACCGCGCGACTCGATTATATTGCGTCACTGGGTGTTGATGCCATCTGGATATCCCCGTTTT
TCAAAAGTCCGCAGGCCGACTACGGCTACGACGTGAGTGACTACCTCGATATCGACCCGCAATTCGGTACGCTGCCTGAC
TTTGAGACACTTATTGAGCGCGCCCACGGTCTGGGTCTTCGGATACTGGTAGATCTGGTCTGGGCGCACACCTCCGACCA
GCATGAATGGTTTGCCGCAAGCCGTGCCAGCCGAACGAATCCGAAAGCCGACTGGTATGTCTGGGCGGACGCGAAAGCCG
ACGGCACGCCTCCAAACAACTGGCAATCCGTGTTTGGCGGGCCTGCCTGGACATGGGATGCACGCCGCGGCCAATATTAC
ATGCATAATTTCCTCTCCGCCCAGCCGCAGCTCAACGGGCACTCTGCGGAAGTTCAGGATGCCTTACTCACGATCGCGCG
CTTCTGGCTCGATCGTGGCGTTGACGGATTCCGGCTGGATGCGCTGAACTACATGATGCACGATCCGGCGCTGACCGATA
ATCCAGCTGCGCCAGAGGATGGCCGACGACGCAGCCGTCCGTATGACTTTCAGCGGCACCAGTACAATCAGAGTCATCCT
GACATTCCGGCTTTTCTGGAACGTGTCCGACAACTGCTTGATAAATATGGAAATCGTTTTGCCGTTGCCGAAGTTGGGGG
CGCCGATACCGACCGCGAAATGAAGCTGTTTACAGCGGACAGCAACCGGCTTCAGTCAGCCTACGGATTTGATTTCTTCT
ATGCCCGCAAGCTGACCCCGTCGGTCGTTCGCTCCGTGCTGGAAAAGTGGCCCGATCGTCCGGGAACGGGATGGCCAAGC
TGGGCATTTGAAAATCACGATGTGCCCCGTGCGCTGTCTCGCTGGTCAGAGCAGAAGTATTTTACGCAGTTCGGGCGGCT
GAAAGCTCTCCTCCTTGCGTCCCTCAGGGGGAACATCTTCTTATATAATGGCGAGGAACTTGGCCTGCCGCATTCGGATC
TGGCATTCGAAGACCTCCGCGATCCGGAAGCGATTGCCAACTGGCCGCTCACGCTTTCACGCGATGGCGCGCGCACGCCG
ATGCCCTGGCAGGAGGATGCCCCTAACCTTGGCTTCAGCGACGCCAGGCCCTGGCTGCCCGCGTGCCCCGAGCACCGTCC
TCTTTCTGTCGAGACGCAGGAGCGCGCCTCCGATTCCCTGCTCGCCTTTACACGCTCTGCTTTGGCTGTCCGCAGGGCCA
GCGCCGCTCTGAGATGGGGCCGGATAGAGTTTATCGAAACGACGGACTCCCTCCTCGCCTTCGAGCGTCAGCATAAGGAC
GAGCGGTTGCTCTGCGTGTTCAATATTGGACCGGAAACACTGCAAACATCTCTGGCAGAGGTGGCGCACGAACCCCTGCT
GGCTACAGGCGCGGCGGAAGGCGGCCAGCTAGGGCCGTTCGCAGGCTTCATTGCGCGTGTGTAG

Upstream 100 bases:

>100_bases
GAACCGGACATTGCAGGGCACCGTCACCGCCTGACCACCCTGGAACCCAAAGCCCCGCACGCTGGCCGCAGACCCAGCCC
TCAACAAGAGAGTGTCAAAT

Downstream 100 bases:

>100_bases
CAGGAGCGAGCCGCAGATCATTACGGCTGTCCTGATAGACATACGGGATCAAATCTACGAGCTTTTAGTCAATATTTATT
GACTTTCTGGGCGCAGCAGT

Product: glycosy hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSEPWWHGATIYQIYPRSFSDSNGDGIGDLPGITARLDYIASLGVDAIWISPFFKSPQADYGYDVSDYLDIDPQFGTLPD
FETLIERAHGLGLRILVDLVWAHTSDQHEWFAASRASRTNPKADWYVWADAKADGTPPNNWQSVFGGPAWTWDARRGQYY
MHNFLSAQPQLNGHSAEVQDALLTIARFWLDRGVDGFRLDALNYMMHDPALTDNPAAPEDGRRRSRPYDFQRHQYNQSHP
DIPAFLERVRQLLDKYGNRFAVAEVGGADTDREMKLFTADSNRLQSAYGFDFFYARKLTPSVVRSVLEKWPDRPGTGWPS
WAFENHDVPRALSRWSEQKYFTQFGRLKALLLASLRGNIFLYNGEELGLPHSDLAFEDLRDPEAIANWPLTLSRDGARTP
MPWQEDAPNLGFSDARPWLPACPEHRPLSVETQERASDSLLAFTRSALAVRRASAALRWGRIEFIETTDSLLAFERQHKD
ERLLCVFNIGPETLQTSLAEVAHEPLLATGAAEGGQLGPFAGFIARV

Sequences:

>Translated_527_residues
MSEPWWHGATIYQIYPRSFSDSNGDGIGDLPGITARLDYIASLGVDAIWISPFFKSPQADYGYDVSDYLDIDPQFGTLPD
FETLIERAHGLGLRILVDLVWAHTSDQHEWFAASRASRTNPKADWYVWADAKADGTPPNNWQSVFGGPAWTWDARRGQYY
MHNFLSAQPQLNGHSAEVQDALLTIARFWLDRGVDGFRLDALNYMMHDPALTDNPAAPEDGRRRSRPYDFQRHQYNQSHP
DIPAFLERVRQLLDKYGNRFAVAEVGGADTDREMKLFTADSNRLQSAYGFDFFYARKLTPSVVRSVLEKWPDRPGTGWPS
WAFENHDVPRALSRWSEQKYFTQFGRLKALLLASLRGNIFLYNGEELGLPHSDLAFEDLRDPEAIANWPLTLSRDGARTP
MPWQEDAPNLGFSDARPWLPACPEHRPLSVETQERASDSLLAFTRSALAVRRASAALRWGRIEFIETTDSLLAFERQHKD
ERLLCVFNIGPETLQTSLAEVAHEPLLATGAAEGGQLGPFAGFIARV
>Mature_526_residues
SEPWWHGATIYQIYPRSFSDSNGDGIGDLPGITARLDYIASLGVDAIWISPFFKSPQADYGYDVSDYLDIDPQFGTLPDF
ETLIERAHGLGLRILVDLVWAHTSDQHEWFAASRASRTNPKADWYVWADAKADGTPPNNWQSVFGGPAWTWDARRGQYYM
HNFLSAQPQLNGHSAEVQDALLTIARFWLDRGVDGFRLDALNYMMHDPALTDNPAAPEDGRRRSRPYDFQRHQYNQSHPD
IPAFLERVRQLLDKYGNRFAVAEVGGADTDREMKLFTADSNRLQSAYGFDFFYARKLTPSVVRSVLEKWPDRPGTGWPSW
AFENHDVPRALSRWSEQKYFTQFGRLKALLLASLRGNIFLYNGEELGLPHSDLAFEDLRDPEAIANWPLTLSRDGARTPM
PWQEDAPNLGFSDARPWLPACPEHRPLSVETQERASDSLLAFTRSALAVRRASAALRWGRIEFIETTDSLLAFERQHKDE
RLLCVFNIGPETLQTSLAEVAHEPLLATGAAEGGQLGPFAGFIARV

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=535, Percent_Identity=31.0280373831776, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI61744483, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61744481, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61744479, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI65506891, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI61744475, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI61744477, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790687, Length=518, Percent_Identity=33.2046332046332, Blast_Score=282, Evalue=4e-77,
Organism=Escherichia coli, GI1786604, Length=188, Percent_Identity=29.7872340425532, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789995, Length=131, Percent_Identity=32.824427480916, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32565753, Length=476, Percent_Identity=23.109243697479, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25147709, Length=396, Percent_Identity=25.5050505050505, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321731, Length=551, Percent_Identity=35.2087114337568, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6319776, Length=551, Percent_Identity=35.2087114337568, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321726, Length=541, Percent_Identity=34.7504621072089, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322245, Length=549, Percent_Identity=32.9690346083789, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6324416, Length=547, Percent_Identity=34.9177330895795, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6322241, Length=547, Percent_Identity=34.9177330895795, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6322021, Length=547, Percent_Identity=34.9177330895795, Blast_Score=291, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24583747, Length=524, Percent_Identity=37.9770992366412, Blast_Score=318, Evalue=4e-87,
Organism=Drosophila melanogaster, GI24583749, Length=524, Percent_Identity=37.9770992366412, Blast_Score=318, Evalue=6e-87,
Organism=Drosophila melanogaster, GI24583745, Length=559, Percent_Identity=35.4203935599284, Blast_Score=312, Evalue=4e-85,
Organism=Drosophila melanogaster, GI24586587, Length=531, Percent_Identity=35.2165725047081, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24586599, Length=531, Percent_Identity=33.1450094161959, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI24586593, Length=517, Percent_Identity=35.0096711798839, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI221330053, Length=552, Percent_Identity=33.1521739130435, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24586597, Length=545, Percent_Identity=32.6605504587156, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI45549022, Length=532, Percent_Identity=32.8947368421053, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24586591, Length=526, Percent_Identity=34.2205323193916, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI24586589, Length=524, Percent_Identity=33.7786259541985, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI281360393, Length=463, Percent_Identity=31.9654427645788, Blast_Score=205, Evalue=8e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 59609; Mature: 59478

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPWWHGATIYQIYPRSFSDSNGDGIGDLPGITARLDYIASLGVDAIWISPFFKSPQAD
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECHHHCCCCCC
YGYDVSDYLDIDPQFGTLPDFETLIERAHGLGLRILVDLVWAHTSDQHEWFAASRASRTN
CCCCHHHHEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PKADWYVWADAKADGTPPNNWQSVFGGPAWTWDARRGQYYMHNFLSAQPQLNGHSAEVQD
CCCCEEEEECCCCCCCCCCCCHHHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCHHHHH
ALLTIARFWLDRGVDGFRLDALNYMMHDPALTDNPAAPEDGRRRSRPYDFQRHQYNQSHP
HHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCHHHHHCCCCCC
DIPAFLERVRQLLDKYGNRFAVAEVGGADTDREMKLFTADSNRLQSAYGFDFFYARKLTP
CHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHCCCHHHHHHCCH
SVVRSVLEKWPDRPGTGWPSWAFENHDVPRALSRWSEQKYFTQFGRLKALLLASLRGNIF
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LYNGEELGLPHSDLAFEDLRDPEAIANWPLTLSRDGARTPMPWQEDAPNLGFSDARPWLP
EECCHHCCCCCCCCCHHHCCCCHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
ACPEHRPLSVETQERASDSLLAFTRSALAVRRASAALRWGRIEFIETTDSLLAFERQHKD
CCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCC
ERLLCVFNIGPETLQTSLAEVAHEPLLATGAAEGGQLGPFAGFIARV
CEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SEPWWHGATIYQIYPRSFSDSNGDGIGDLPGITARLDYIASLGVDAIWISPFFKSPQAD
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECHHHCCCCCC
YGYDVSDYLDIDPQFGTLPDFETLIERAHGLGLRILVDLVWAHTSDQHEWFAASRASRTN
CCCCHHHHEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PKADWYVWADAKADGTPPNNWQSVFGGPAWTWDARRGQYYMHNFLSAQPQLNGHSAEVQD
CCCCEEEEECCCCCCCCCCCCHHHCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCHHHHH
ALLTIARFWLDRGVDGFRLDALNYMMHDPALTDNPAAPEDGRRRSRPYDFQRHQYNQSHP
HHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCHHHHHCCCCCC
DIPAFLERVRQLLDKYGNRFAVAEVGGADTDREMKLFTADSNRLQSAYGFDFFYARKLTP
CHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHCCCHHHHHHCCH
SVVRSVLEKWPDRPGTGWPSWAFENHDVPRALSRWSEQKYFTQFGRLKALLLASLRGNIF
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
LYNGEELGLPHSDLAFEDLRDPEAIANWPLTLSRDGARTPMPWQEDAPNLGFSDARPWLP
EECCHHCCCCCCCCCHHHCCCCHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
ACPEHRPLSVETQERASDSLLAFTRSALAVRRASAALRWGRIEFIETTDSLLAFERQHKD
CCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCC
ERLLCVFNIGPETLQTSLAEVAHEPLLATGAAEGGQLGPFAGFIARV
CEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]