| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is ilvX [H]
Identifier: 114798777
GI number: 114798777
Start: 884345
End: 885892
Strand: Direct
Name: ilvX [H]
Synonym: HNE_0865
Alternate gene names: 114798777
Gene position: 884345-885892 (Clockwise)
Preceding gene: 114797749
Following gene: 114798532
Centisome position: 23.87
GC content: 68.09
Gene sequence:
>1548_bases ATGACCGGCGCCGAGGCGCTTGTGTCCACACTAGCCGATCATGGCGTCACGGCCTGCTTCGCCAATCCCGGCACCTCTGA AATGCACCTCGTCACCGCGCTCGACCGCGAGCCGCGCATCCGCTCGGTGCTCTGCCTGTTTGAGGGTGTGGCGACCGGCG CCGCAGACGGCTACGCCCGCGTCACAGGCCGCCCGGCGATGACGCTGCTGCATCTGGGCGCCGGCTTCATGAATGGCGGG GCCAACATCCACAACGCCAAGCGCGCCTGGACCCCGATGATCAACGTCATCGGCGATCATTCGGTGCCGCACCTGCGCTA TGACGCGCCGCTCACCTCCAACATCATGGGCCTCGCCGGGCCAAACTCGGTCTGGATCAAATCGGCCAACCATGTCTCTG TCACGGGCGATCTGGCGGCCGAAGCCTGGGCCGCCAGCTTTGGCCCTGTGCCCGGCCCGGTCTCGCTGATCCTCCCGGCG GACTCCGCCTGGACCGAAGGCGCCACCCCCGGCAAGACGCGCGCTCAGCCCTTCCTGCGCGCGCCCGATACTGCGCTCGT CGAAGCCGCTGCCAAGGCTGTGAAGTCCGCCAAAAAACCGATGATCCTGATCAGCGGCACCGCGCTCACCGGTCCCGGCC TCGGCCATGCTGCGCGCCTGAAAGCGGCCGGCATCCGTGTGCTGACGGATACGTTCTTCCCCCGCCAGGTACGCGGCGCG GGCATCTTCGCGCCCGAGCGGATGCAGTATTTTGCCGAAGGCGCGATGGCAGACCTTGAAGGCACCGACCTGATGCTGGT GGCCGGCACACAGGTGCCCGTCGCCTTCTTCGCTTATCCCGGCAAGCCGAGCCTGCTTGTGCCCGAAGGCTGCACACCGA TGGTGCTCGGCGGGCCGGAAAGCGACAGCGCCGCCATCCTCGAAGCTCTCGCCGATACCATGGGCCTCACCGAGGCAGCG CCTGCGCCTACGCTGGAAATTCCAGACGCCCCGACCGGCGCGCTCAATGCCGCCACCATCGGCGCCTCCATCGCGCGGCA TATGCCCGAGGGCACATTCGTCTCTGATGATGGCGTTTCCAACGGTCTGCCGAGCTTCATGATGACCGGCCGCGCCCGCC CGCATGACTGGATGATGCTGACCGGCGGCGCGATCGGGCAGGGCATGCCCCTCGCGCTCGGCGCTGCCATCGGTGCCAAG GGCCGCAAGGTGCTCTGCCTCACGGGCGATGGCGCAGGCATGTACACCAACCAGGCGCTCTGGAGCATGGCGCGCGAGAA AGCCGATGTGATTAACATCGTCTTCGTCAACCATTCCTACCGTATCCTGAACATCGAGCTGGCGCGCACCGGCGCGGGCA ATCCCGGCCGCGTGGCGGCAGACCTCCTCGGCCTCGGCCGCCCGGAGATCGACTGGGTGAAGCTGTCGGAAGCCCAGGGC GTCCCGGCGGTCAACGCCACCACCGCCGAAGAATTCGACGCAGCCCTCGCCCGCGCCTTCAGCGAGCCGGGCCCCCACCT GATCGCCGCGCACGTTCCCGCGCGCTAG
Upstream 100 bases:
>100_bases GCCTGCGGCCCGTTTGGTTTTGCGCTCGCGCCGAAAACCGCTAGGGAACGCCAACAACTCAATCAGGGGAGGTTTGTCCA TGTCCGATTCCGACGCCGCC
Downstream 100 bases:
>100_bases GCACAAAAAAACTCAGCCGCCTGACGCATCAGGCGGCTGAGCTGTTTTCAGTTCAGGTCCGGAAAATCACTCGGCCGCGT CGGCGTCCACCTCATCCTTC
Product: hypothetical protein
Products: NA
Alternate protein names: ALS; Acetohydroxy-acid synthase large subunit; AHAS [H]
Number of amino acids: Translated: 515; Mature: 514
Protein sequence:
>515_residues MTGAEALVSTLADHGVTACFANPGTSEMHLVTALDREPRIRSVLCLFEGVATGAADGYARVTGRPAMTLLHLGAGFMNGG ANIHNAKRAWTPMINVIGDHSVPHLRYDAPLTSNIMGLAGPNSVWIKSANHVSVTGDLAAEAWAASFGPVPGPVSLILPA DSAWTEGATPGKTRAQPFLRAPDTALVEAAAKAVKSAKKPMILISGTALTGPGLGHAARLKAAGIRVLTDTFFPRQVRGA GIFAPERMQYFAEGAMADLEGTDLMLVAGTQVPVAFFAYPGKPSLLVPEGCTPMVLGGPESDSAAILEALADTMGLTEAA PAPTLEIPDAPTGALNAATIGASIARHMPEGTFVSDDGVSNGLPSFMMTGRARPHDWMMLTGGAIGQGMPLALGAAIGAK GRKVLCLTGDGAGMYTNQALWSMAREKADVINIVFVNHSYRILNIELARTGAGNPGRVAADLLGLGRPEIDWVKLSEAQG VPAVNATTAEEFDAALARAFSEPGPHLIAAHVPAR
Sequences:
>Translated_515_residues MTGAEALVSTLADHGVTACFANPGTSEMHLVTALDREPRIRSVLCLFEGVATGAADGYARVTGRPAMTLLHLGAGFMNGG ANIHNAKRAWTPMINVIGDHSVPHLRYDAPLTSNIMGLAGPNSVWIKSANHVSVTGDLAAEAWAASFGPVPGPVSLILPA DSAWTEGATPGKTRAQPFLRAPDTALVEAAAKAVKSAKKPMILISGTALTGPGLGHAARLKAAGIRVLTDTFFPRQVRGA GIFAPERMQYFAEGAMADLEGTDLMLVAGTQVPVAFFAYPGKPSLLVPEGCTPMVLGGPESDSAAILEALADTMGLTEAA PAPTLEIPDAPTGALNAATIGASIARHMPEGTFVSDDGVSNGLPSFMMTGRARPHDWMMLTGGAIGQGMPLALGAAIGAK GRKVLCLTGDGAGMYTNQALWSMAREKADVINIVFVNHSYRILNIELARTGAGNPGRVAADLLGLGRPEIDWVKLSEAQG VPAVNATTAEEFDAALARAFSEPGPHLIAAHVPAR >Mature_514_residues TGAEALVSTLADHGVTACFANPGTSEMHLVTALDREPRIRSVLCLFEGVATGAADGYARVTGRPAMTLLHLGAGFMNGGA NIHNAKRAWTPMINVIGDHSVPHLRYDAPLTSNIMGLAGPNSVWIKSANHVSVTGDLAAEAWAASFGPVPGPVSLILPAD SAWTEGATPGKTRAQPFLRAPDTALVEAAAKAVKSAKKPMILISGTALTGPGLGHAARLKAAGIRVLTDTFFPRQVRGAG IFAPERMQYFAEGAMADLEGTDLMLVAGTQVPVAFFAYPGKPSLLVPEGCTPMVLGGPESDSAAILEALADTMGLTEAAP APTLEIPDAPTGALNAATIGASIARHMPEGTFVSDDGVSNGLPSFMMTGRARPHDWMMLTGGAIGQGMPLALGAAIGAKG RKVLCLTGDGAGMYTNQALWSMAREKADVINIVFVNHSYRILNIELARTGAGNPGRVAADLLGLGRPEIDWVKLSEAQGV PAVNATTAEEFDAALARAFSEPGPHLIAAHVPAR
Specific function: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine [H]
COG id: COG0028
COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the TPP enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1790104, Length=559, Percent_Identity=23.0769230769231, Blast_Score=94, Evalue=2e-20, Organism=Escherichia coli, GI87081685, Length=553, Percent_Identity=23.1464737793852, Blast_Score=81, Evalue=2e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012001 - InterPro: IPR011766 [H]
Pfam domain/function: PF02775 TPP_enzyme_C; PF02776 TPP_enzyme_N [H]
EC number: =2.2.1.6 [H]
Molecular weight: Translated: 53189; Mature: 53057
Theoretical pI: Translated: 6.45; Mature: 6.45
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGAEALVSTLADHGVTACFANPGTSEMHLVTALDREPRIRSVLCLFEGVATGAADGYAR CCHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEE VTGRPAMTLLHLGAGFMNGGANIHNAKRAWTPMINVIGDHSVPHLRYDAPLTSNIMGLAG ECCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCEEECCC PNSVWIKSANHVSVTGDLAAEAWAASFGPVPGPVSLILPADSAWTEGATPGKTRAQPFLR CCCEEEECCCEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC APDTALVEAAAKAVKSAKKPMILISGTALTGPGLGHAARLKAAGIRVLTDTFFPRQVRGA CCCHHHHHHHHHHHHHCCCCEEEEECCEECCCCCCHHHHHHHCCEEEEECCCCCHHHCCC GIFAPERMQYFAEGAMADLEGTDLMLVAGTQVPVAFFAYPGKPSLLVPEGCTPMVLGGPE CCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEECCCCCCEEEECCCC SDSAAILEALADTMGLTEAAPAPTLEIPDAPTGALNAATIGASIARHMPEGTFVSDDGVS CCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCC NGLPSFMMTGRARPHDWMMLTGGAIGQGMPLALGAAIGAKGRKVLCLTGDGAGMYTNQAL CCCCHHHHCCCCCCCCEEEEECCCCCCCCCEEEHHHCCCCCCEEEEEECCCCCCCHHHHH WSMAREKADVINIVFVNHSYRILNIELARTGAGNPGRVAADLLGLGRPEIDWVKLSEAQG HHHHHCCCCEEEEEEEECCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCC VPAVNATTAEEFDAALARAFSEPGPHLIAAHVPAR CCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC >Mature Secondary Structure TGAEALVSTLADHGVTACFANPGTSEMHLVTALDREPRIRSVLCLFEGVATGAADGYAR CHHHHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEE VTGRPAMTLLHLGAGFMNGGANIHNAKRAWTPMINVIGDHSVPHLRYDAPLTSNIMGLAG ECCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCEEECCC PNSVWIKSANHVSVTGDLAAEAWAASFGPVPGPVSLILPADSAWTEGATPGKTRAQPFLR CCCEEEECCCEEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC APDTALVEAAAKAVKSAKKPMILISGTALTGPGLGHAARLKAAGIRVLTDTFFPRQVRGA CCCHHHHHHHHHHHHHCCCCEEEEECCEECCCCCCHHHHHHHCCEEEEECCCCCHHHCCC GIFAPERMQYFAEGAMADLEGTDLMLVAGTQVPVAFFAYPGKPSLLVPEGCTPMVLGGPE CCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEECCCCCCEECCCCCCEEEECCCC SDSAAILEALADTMGLTEAAPAPTLEIPDAPTGALNAATIGASIARHMPEGTFVSDDGVS CCHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCC NGLPSFMMTGRARPHDWMMLTGGAIGQGMPLALGAAIGAKGRKVLCLTGDGAGMYTNQAL CCCCHHHHCCCCCCCCEEEEECCCCCCCCCEEEHHHCCCCCCEEEEEECCCCCCCHHHHH WSMAREKADVINIVFVNHSYRILNIELARTGAGNPGRVAADLLGLGRPEIDWVKLSEAQG HHHHHCCCCEEEEEEEECCEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCC VPAVNATTAEEFDAALARAFSEPGPHLIAAHVPAR CCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230 [H]