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The map label for this gene is nuoL [H]

Identifier: 114798733

GI number: 114798733

Start: 1796212

End: 1798362

Strand: Direct

Name: nuoL [H]

Synonym: HNE_1756

Alternate gene names: 114798733

Gene position: 1796212-1798362 (Clockwise)

Preceding gene: 114799864

Following gene: 114797733

Centisome position: 48.48

GC content: 57.32

Gene sequence:

>2151_bases
ATGCTTCCTGATAGCCTTCTTCTTTTTATTGTTCTGGCGCCGGGCATCGCCGCTCTTTTTGGCTTGTTCCACAAGGTAGT
CGGCGATCGCACTGTGATGCTTGTCACCACGGGAACCGTCCTGACGGCCGGTGCCCTTTCCCTGTTTCAACTGTTCGCTT
ATGTAGCCGGACTTGGGCATGTTGGGGCGCCGGAAGCGCATGCCGCCGTAGACGCCTATCTGACCGCCGGGCCCGCGCAC
AGCACGCAGGAGCTGAAGCAGCATATCATTACACTCATGCCCTGGATTGAAGTCGGGAACTTCAAGGCTAACTGGGCAAT
CCGGGTTGATGCGCTGTCGATTGTCATGATGGCGGTGATTACGGGCGTTTCTGGTCTCGTTCACCTCTATTCCTGGGGCT
ATATGAGCGAGGAGCCGCACAAGTCGCGCTTTTTTGCCTACCTTTCACTCTTCACCTTCATGATGCTCATGCTGGTGGTG
GCCGACAACTTCATCCAGCTGTTCTTCGGCTGGGAAGGCGTGGGGCTCGCCTCCTATTTGCTGATCGGTTTCTGGTACAC
CAAGAAGGCGCCTAACGACGCGTCCATCAAGGCATTCGTTACCAACCGCGTCGGAGATTTCGGGCTGGCGCTCGGTATCA
TGGCTGTGTTCTTCGTGTTTGGCAGTGTCGAATTTGGTCCCGTCCTGGATGCGATCCGCACCAATGCCATCGTCACGCCG
GTTGCTTTTGCAGAAGCCGCTCCCGCGCGGGAAGCGGTGATCATGTTCCTTGGGCAGCGCGTCTATGCGCTGGAGCTGAT
CGGCATCCTTCTGTTCATTGGTGCTATGGGCAAATCGGCTCAGTTCTTCCTGCATGTCTGGCTCCCAGACGCCATGGAAG
GTCCGACCCCTGTATCCGCGCTCATTCATGCGGCAACGATGGTGACGGCGGGCGTGTATCTCGTCTGCCTCGTCTCACCG
ATTTACGAATACACGTTCTATGCAGCTGGCATGATCGCCCTGGTGGGGGCAGTCACGGCGCTCTACGCCGCCACCGTCGG
CATGGCGCAGAACGACATCAAACGCGTGATTGCGTATTCGACCTGTTCGCAGCTTGGCTACATGTTCTTTGCCGCCGGTG
TCGGCGCTTATGAAGCCGCGATGTTCCATCTTTTTACTCACGCCTTCTTCAAGGCGCTGCTGTTCCTCGGGGCCGGCTCG
GTCATCCACGGTATGCACCATGAACAGGACATGCGCCGCATGGGCGGGCTCGCGAAGTTCATGCCGCTGACCTATGCGGC
GATGATGATCGGCACGATCGCCATCATCGGCCTCGGCATTCCGCACACGAAGTTGGGCTTTTCAGGCTTTTTCTCAAAGG
ACGCCATTCTCGAAAGCGCCTTCGCTGGTGGCACAGCGCAAGTCATGTTCGGCCAAATGGCATTTTGGTTTGGTCTGCTA
GCGGCGTTTCTGACCAGCTTCTATTCCTGGCGCCTCATTTACATGACCTTCCATGGACCGCGGGTTGTACTCGAAGATCA
TGGCCACGATCATGCGCACGCGGATGAGCACGCTGAGGATGACCATCACGGTCACGATCACACGCCGCACGAAAGCCCGA
TGGTGATGCTTATCCCATTGGCGCTCTTGAGCCTCGGGGCAGTTTTTGCGGGGTTCTATTTCTACGACGCATTTGTCGAG
GCCAATAACGAAGCCTTCTGGGCGGGCGCGATCTATCGCGCTACGGAAAACCACGTACTGCACGATCGCCACAATGTGCC
GGAATGGGTTCTATGGGCGCCGCTTGTCGTAACGATCGCCGGCTTCGCTCTGGCGAGCATGACTTACTTCTTCAATCGCG
GTGTTGGTGCGCGCATCGCCGCAAGTGGTGGCCCGCTCCACTCGCTTTTCTCCAATAAATGGTATTTCGACGAGATCTAC
CAAGCCACGCTGGTTCGCGGGTCAGCTTTCCTCGGCAATATATTCTGGAAAGCAGACAAGAAGATCATTGATGGTGCCGG
CCCTGACGGAATGGCTGCGCTTGCAGGCATTGGCGCCCGGCGTCTGGCAAAAATGCACACGGGTTATCTGTATCACTATG
CCTTCGTGATCATCGGGGCGGCCATCGTATTTGGCGCGATCCTGTGGTTGCGGGCAGGAGGGGCCAACTGA

Upstream 100 bases:

>100_bases
GCTGAAGCCGCGGTCGGGCTTGCCATCCTCGTCGTATATTTCCGTAACCGTCGCGACATCTCGGTTGAGAATGTCGACCT
GATGAAGGGCTGATAAGGGT

Downstream 100 bases:

>100_bases
TGGGCGGTTTCCCCATTCTTACCGCGATGACGTTCCTGCCGTTGATCGGCGCGTTGCTCATCGTTCTCGTCCGCGCGGCC
ACTGCAGGAAGCCGCGCTGC

Product: NADH-quinone oxidoreductase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MLPDSLLLFIVLAPGIAALFGLFHKVVGDRTVMLVTTGTVLTAGALSLFQLFAYVAGLGHVGAPEAHAAVDAYLTAGPAH
STQELKQHIITLMPWIEVGNFKANWAIRVDALSIVMMAVITGVSGLVHLYSWGYMSEEPHKSRFFAYLSLFTFMMLMLVV
ADNFIQLFFGWEGVGLASYLLIGFWYTKKAPNDASIKAFVTNRVGDFGLALGIMAVFFVFGSVEFGPVLDAIRTNAIVTP
VAFAEAAPAREAVIMFLGQRVYALELIGILLFIGAMGKSAQFFLHVWLPDAMEGPTPVSALIHAATMVTAGVYLVCLVSP
IYEYTFYAAGMIALVGAVTALYAATVGMAQNDIKRVIAYSTCSQLGYMFFAAGVGAYEAAMFHLFTHAFFKALLFLGAGS
VIHGMHHEQDMRRMGGLAKFMPLTYAAMMIGTIAIIGLGIPHTKLGFSGFFSKDAILESAFAGGTAQVMFGQMAFWFGLL
AAFLTSFYSWRLIYMTFHGPRVVLEDHGHDHAHADEHAEDDHHGHDHTPHESPMVMLIPLALLSLGAVFAGFYFYDAFVE
ANNEAFWAGAIYRATENHVLHDRHNVPEWVLWAPLVVTIAGFALASMTYFFNRGVGARIAASGGPLHSLFSNKWYFDEIY
QATLVRGSAFLGNIFWKADKKIIDGAGPDGMAALAGIGARRLAKMHTGYLYHYAFVIIGAAIVFGAILWLRAGGAN

Sequences:

>Translated_716_residues
MLPDSLLLFIVLAPGIAALFGLFHKVVGDRTVMLVTTGTVLTAGALSLFQLFAYVAGLGHVGAPEAHAAVDAYLTAGPAH
STQELKQHIITLMPWIEVGNFKANWAIRVDALSIVMMAVITGVSGLVHLYSWGYMSEEPHKSRFFAYLSLFTFMMLMLVV
ADNFIQLFFGWEGVGLASYLLIGFWYTKKAPNDASIKAFVTNRVGDFGLALGIMAVFFVFGSVEFGPVLDAIRTNAIVTP
VAFAEAAPAREAVIMFLGQRVYALELIGILLFIGAMGKSAQFFLHVWLPDAMEGPTPVSALIHAATMVTAGVYLVCLVSP
IYEYTFYAAGMIALVGAVTALYAATVGMAQNDIKRVIAYSTCSQLGYMFFAAGVGAYEAAMFHLFTHAFFKALLFLGAGS
VIHGMHHEQDMRRMGGLAKFMPLTYAAMMIGTIAIIGLGIPHTKLGFSGFFSKDAILESAFAGGTAQVMFGQMAFWFGLL
AAFLTSFYSWRLIYMTFHGPRVVLEDHGHDHAHADEHAEDDHHGHDHTPHESPMVMLIPLALLSLGAVFAGFYFYDAFVE
ANNEAFWAGAIYRATENHVLHDRHNVPEWVLWAPLVVTIAGFALASMTYFFNRGVGARIAASGGPLHSLFSNKWYFDEIY
QATLVRGSAFLGNIFWKADKKIIDGAGPDGMAALAGIGARRLAKMHTGYLYHYAFVIIGAAIVFGAILWLRAGGAN
>Mature_716_residues
MLPDSLLLFIVLAPGIAALFGLFHKVVGDRTVMLVTTGTVLTAGALSLFQLFAYVAGLGHVGAPEAHAAVDAYLTAGPAH
STQELKQHIITLMPWIEVGNFKANWAIRVDALSIVMMAVITGVSGLVHLYSWGYMSEEPHKSRFFAYLSLFTFMMLMLVV
ADNFIQLFFGWEGVGLASYLLIGFWYTKKAPNDASIKAFVTNRVGDFGLALGIMAVFFVFGSVEFGPVLDAIRTNAIVTP
VAFAEAAPAREAVIMFLGQRVYALELIGILLFIGAMGKSAQFFLHVWLPDAMEGPTPVSALIHAATMVTAGVYLVCLVSP
IYEYTFYAAGMIALVGAVTALYAATVGMAQNDIKRVIAYSTCSQLGYMFFAAGVGAYEAAMFHLFTHAFFKALLFLGAGS
VIHGMHHEQDMRRMGGLAKFMPLTYAAMMIGTIAIIGLGIPHTKLGFSGFFSKDAILESAFAGGTAQVMFGQMAFWFGLL
AAFLTSFYSWRLIYMTFHGPRVVLEDHGHDHAHADEHAEDDHHGHDHTPHESPMVMLIPLALLSLGAVFAGFYFYDAFVE
ANNEAFWAGAIYRATENHVLHDRHNVPEWVLWAPLVVTIAGFALASMTYFFNRGVGARIAASGGPLHSLFSNKWYFDEIY
QATLVRGSAFLGNIFWKADKKIIDGAGPDGMAALAGIGARRLAKMHTGYLYHYAFVIIGAAIVFGAILWLRAGGAN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=470, Percent_Identity=35.9574468085106, Blast_Score=276, Evalue=4e-74,
Organism=Escherichia coli, GI1788614, Length=645, Percent_Identity=38.1395348837209, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI1788829, Length=383, Percent_Identity=30.5483028720627, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1788827, Length=396, Percent_Identity=29.5454545454545, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788831, Length=378, Percent_Identity=28.042328042328, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788613, Length=362, Percent_Identity=28.1767955801105, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI2367154, Length=119, Percent_Identity=31.0924369747899, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 77807; Mature: 77807

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDSLLLFIVLAPGIAALFGLFHKVVGDRTVMLVTTGTVLTAGALSLFQLFAYVAGLGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
VGAPEAHAAVDAYLTAGPAHSTQELKQHIITLMPWIEVGNFKANWAIRVDALSIVMMAVI
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCEEECEEEEHHHHHHHHHHHH
TGVSGLVHLYSWGYMSEEPHKSRFFAYLSLFTFMMLMLVVADNFIQLFFGWEGVGLASYL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LIGFWYTKKAPNDASIKAFVTNRVGDFGLALGIMAVFFVFGSVEFGPVLDAIRTNAIVTP
HHHHHHHCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECH
VAFAEAAPAREAVIMFLGQRVYALELIGILLFIGAMGKSAQFFLHVWLPDAMEGPTPVSA
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHH
LIHAATMVTAGVYLVCLVSPIYEYTFYAAGMIALVGAVTALYAATVGMAQNDIKRVIAYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TCSQLGYMFFAAGVGAYEAAMFHLFTHAFFKALLFLGAGSVIHGMHHEQDMRRMGGLAKF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHH
MPLTYAAMMIGTIAIIGLGIPHTKLGFSGFFSKDAILESAFAGGTAQVMFGQMAFWFGLL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AAFLTSFYSWRLIYMTFHGPRVVLEDHGHDHAHADEHAEDDHHGHDHTPHESPMVMLIPL
HHHHHHHHCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ALLSLGAVFAGFYFYDAFVEANNEAFWAGAIYRATENHVLHDRHNVPEWVLWAPLVVTIA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHH
GFALASMTYFFNRGVGARIAASGGPLHSLFSNKWYFDEIYQATLVRGSAFLGNIFWKADK
HHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHCCC
KIIDGAGPDGMAALAGIGARRLAKMHTGYLYHYAFVIIGAAIVFGAILWLRAGGAN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLPDSLLLFIVLAPGIAALFGLFHKVVGDRTVMLVTTGTVLTAGALSLFQLFAYVAGLGH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
VGAPEAHAAVDAYLTAGPAHSTQELKQHIITLMPWIEVGNFKANWAIRVDALSIVMMAVI
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEECCEEECEEEEHHHHHHHHHHHH
TGVSGLVHLYSWGYMSEEPHKSRFFAYLSLFTFMMLMLVVADNFIQLFFGWEGVGLASYL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LIGFWYTKKAPNDASIKAFVTNRVGDFGLALGIMAVFFVFGSVEFGPVLDAIRTNAIVTP
HHHHHHHCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECH
VAFAEAAPAREAVIMFLGQRVYALELIGILLFIGAMGKSAQFFLHVWLPDAMEGPTPVSA
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHH
LIHAATMVTAGVYLVCLVSPIYEYTFYAAGMIALVGAVTALYAATVGMAQNDIKRVIAYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TCSQLGYMFFAAGVGAYEAAMFHLFTHAFFKALLFLGAGSVIHGMHHEQDMRRMGGLAKF
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHH
MPLTYAAMMIGTIAIIGLGIPHTKLGFSGFFSKDAILESAFAGGTAQVMFGQMAFWFGLL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AAFLTSFYSWRLIYMTFHGPRVVLEDHGHDHAHADEHAEDDHHGHDHTPHESPMVMLIPL
HHHHHHHHCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ALLSLGAVFAGFYFYDAFVEANNEAFWAGAIYRATENHVLHDRHNVPEWVLWAPLVVTIA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHH
GFALASMTYFFNRGVGARIAASGGPLHSLFSNKWYFDEIYQATLVRGSAFLGNIFWKADK
HHHHHHHHHHHHCCCCCEEECCCCCHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHCCC
KIIDGAGPDGMAALAGIGARRLAKMHTGYLYHYAFVIIGAAIVFGAILWLRAGGAN
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]