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The map label for this gene is higA [H]

Identifier: 114798692

GI number: 114798692

Start: 2826189

End: 2826482

Strand: Reverse

Name: higA [H]

Synonym: HNE_2664

Alternate gene names: 114798692

Gene position: 2826482-2826189 (Counterclockwise)

Preceding gene: 114799282

Following gene: 114797374

Centisome position: 76.29

GC content: 55.78

Gene sequence:

>294_bases
ATGACGACCTTGAAAGTGCCGGTCCATCCCGGTGAAATTCTCCGCTATGAGTTTCTCGAGCCGATGGGCCTCAGCCCGAT
CCGGCTTGCAAAACATATCCGCGTGCCGCGTACGCGGATTGAGCGGCTGATAAAGGAAGAGACGGCCCTGACGATCGACA
CCGCCAAACGCCTTGCCCGGGCTTTTGGCACGAGTGTCGAGTTCTGGATGAATCTTCAGATGAGCTATGACCTGCTCAAG
GCCGAGGCAGATATTGATGTCTCGCTTATCGAGCCGCTTACTGCAGCCCAATAA

Upstream 100 bases:

>100_bases
TTCGATCCGGATCAACGACCAGTGGCGCATCTGTTTTATCTGGGGCGACATTGGCCCGGAAGATGTTGAGATCGTGGATT
ATCATTGAGAGGAGATGGCG

Downstream 100 bases:

>100_bases
GATAGAGTGTGAAACCTGGCACGGAGCGCTGAGGCTATAAGGTCTCAGCGCTCCGTCCGGGGATGCGCGCCGTTCTGGCG
CGCTCAGCCCCCTGACCCCC

Product: addiction module antidote protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MTTLKVPVHPGEILRYEFLEPMGLSPIRLAKHIRVPRTRIERLIKEETALTIDTAKRLARAFGTSVEFWMNLQMSYDLLK
AEADIDVSLIEPLTAAQ

Sequences:

>Translated_97_residues
MTTLKVPVHPGEILRYEFLEPMGLSPIRLAKHIRVPRTRIERLIKEETALTIDTAKRLARAFGTSVEFWMNLQMSYDLLK
AEADIDVSLIEPLTAAQ
>Mature_96_residues
TTLKVPVHPGEILRYEFLEPMGLSPIRLAKHIRVPRTRIERLIKEETALTIDTAKRLARAFGTSVEFWMNLQMSYDLLKA
EADIDVSLIEPLTAAQ

Specific function: Unknown

COG id: COG3093

COG function: function code R; Plasmid maintenance system antidote protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081745, Length=79, Percent_Identity=43.0379746835443, Blast_Score=71, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013430
- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: PF01381 HTH_3 [H]

EC number: NA

Molecular weight: Translated: 11077; Mature: 10946

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLKVPVHPGEILRYEFLEPMGLSPIRLAKHIRVPRTRIERLIKEETALTIDTAKRLAR
CCEEECCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHH
AFGTSVEFWMNLQMSYDLLKAEADIDVSLIEPLTAAQ
HHCCCEEEEEEHHHHHHHHHCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
TTLKVPVHPGEILRYEFLEPMGLSPIRLAKHIRVPRTRIERLIKEETALTIDTAKRLAR
CEEECCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHH
AFGTSVEFWMNLQMSYDLLKAEADIDVSLIEPLTAAQ
HHCCCEEEEEEHHHHHHHHHCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8169216 [H]