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The map label for this gene is ycgO [H]

Identifier: 114798589

GI number: 114798589

Start: 1087864

End: 1089312

Strand: Direct

Name: ycgO [H]

Synonym: HNE_1081

Alternate gene names: 114798589

Gene position: 1087864-1089312 (Clockwise)

Preceding gene: 114797911

Following gene: 114800160

Centisome position: 29.36

GC content: 65.91

Gene sequence:

>1449_bases
GTGCGGGCAAATCTTCCAGCGCTGATTACGCTGATAGTCTATGCGGTGTTGCTTGTAGGTGTCAGCCTGTGGGCGAGCCG
CAAGGTGCGCTCGGAGGCGTCGTCTTTTCTTCTGGGCGGGCGCTCTCTGGGGCCGCTGGTTTCGGGGCTTGCCTATGCCG
CTTCGAGTTCCAGCGCGTGGGTGCTGCTGGGCTATTCGGGCTTTGTGTATGCGACGGGGCTTTCGGCGCTGTGGATGATC
CCCGGCATTCTGCTGGGCTATGGCGCGGTGTGGCTGTTTGCGGGGCCGGTGTTGCAGGCGGCAAGCCGGGACAAGGACCA
GCTGACGCTGACAGCGTTCCTGACCGAGACGGCCGGGCCGCGCGTGGCGCGCCTGATCCGGATTTCGGCGACGGTGATGA
TCGCCTTCTGTTTTTCCTACTATATCGCGTCTCAGTTCCAGGGCGCGGGCGTGGCGTTTGACGATCTCTTCGGTATCGGG
ATGAGCGGCGGCATCATTCTCGGGGCGATTATCATTCTGGCCTACACATTTGCGGGCGGGTTTCTGGCGGTTTCGGTGAT
CAATACCGTGCAGGGCGTGATCATGATGCTCGTCGCGATCCTGTTGCCGGTGCTGGCATTCTCTGCGGCGGGCGGGGTGA
GTGGCATCGGCGCGGCGCTGGAGGATGTGCCCCCTGAGTATCTCGCGACATTCGGCGGGCGTGCGGGATGGATCGCGGGC
GGCTTTGCGCTCGGCATGACGGCGACGGGATTTGGCGCGCTGGGCCAGCCCCACCTCATCAGCTGGATCATGGCAGCGCG
GGACACCAAAGCGCGCGTAATGGGCGCGGGCGTGGCGATCGGCTGGGGCGCGGTAGTCTATGCCGGGATGGCGGTGCTGG
GGCTTTCGGGGCGGGCGCTGTTTGGCGCCGACGCGCCGGCGGAAGGCATCTTCTTCAAGCTGGCCGGCGATTTGTTGCCG
GGCGTTCTGGCGGGGATCGTGGCGGCGGCGATCCTCTCGGCGATCATGTCGACGGTGGATAGCCAGTTGCTGGTGGCAAG
CGGGGCGATCAGCCATGACCTTGGCGCGGCGCGTTTGATGGGCGGACGCACAGTGCTGGCGACGCGGTTGGCGATGCTGG
TTGTGAGCGGGGTTGCGGTCGTGCTGACGCTGGCCTTGCCCGCGACGATCTTTGACCGGACGCTGTTTGCGTGGACGGCG
CTGGGGGCGAGTTTCGGGCCGGTGGTGGTCGTGAGGGCGTTTGGCGGGCGGCCGGGCGGCGCCGCGGTGCTCGCGTCGAT
CCTGGCGGGCTTTGTGACCTCGCTGGCTTATGAATTTGTCCTGAATTCCGGGCCGGGCGCCGTGTGGGCACGGACGGTTC
CGTGGATCGCTGCCTTTCTGGCGCTCGCCGTGACCAGAATTGTTGCAGGGCAGCACAATCAGGCGCTTGGCGCGCCTTCC
GACTTGTGA

Upstream 100 bases:

>100_bases
GGAGCTTTATGGCTTCACCCCGAAGGCGGGTCTGCCGCTGGGATTTAAAGGTGAGCCGGTGCCGGCTCCGGTGGCAGCTG
GCTAAAAAAGCGGGGGCGGG

Downstream 100 bases:

>100_bases
GATGCAAAAGATATAACAATAAAAGATATATCTAACGGAGGAACCCATGCACACCGCTCGTTATCTGGCGCTGGCTGCTG
CAGCCTTTCTGGTGTCTGCC

Product: cation/acetate symporter ActP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MRANLPALITLIVYAVLLVGVSLWASRKVRSEASSFLLGGRSLGPLVSGLAYAASSSSAWVLLGYSGFVYATGLSALWMI
PGILLGYGAVWLFAGPVLQAASRDKDQLTLTAFLTETAGPRVARLIRISATVMIAFCFSYYIASQFQGAGVAFDDLFGIG
MSGGIILGAIIILAYTFAGGFLAVSVINTVQGVIMMLVAILLPVLAFSAAGGVSGIGAALEDVPPEYLATFGGRAGWIAG
GFALGMTATGFGALGQPHLISWIMAARDTKARVMGAGVAIGWGAVVYAGMAVLGLSGRALFGADAPAEGIFFKLAGDLLP
GVLAGIVAAAILSAIMSTVDSQLLVASGAISHDLGAARLMGGRTVLATRLAMLVVSGVAVVLTLALPATIFDRTLFAWTA
LGASFGPVVVVRAFGGRPGGAAVLASILAGFVTSLAYEFVLNSGPGAVWARTVPWIAAFLALAVTRIVAGQHNQALGAPS
DL

Sequences:

>Translated_482_residues
MRANLPALITLIVYAVLLVGVSLWASRKVRSEASSFLLGGRSLGPLVSGLAYAASSSSAWVLLGYSGFVYATGLSALWMI
PGILLGYGAVWLFAGPVLQAASRDKDQLTLTAFLTETAGPRVARLIRISATVMIAFCFSYYIASQFQGAGVAFDDLFGIG
MSGGIILGAIIILAYTFAGGFLAVSVINTVQGVIMMLVAILLPVLAFSAAGGVSGIGAALEDVPPEYLATFGGRAGWIAG
GFALGMTATGFGALGQPHLISWIMAARDTKARVMGAGVAIGWGAVVYAGMAVLGLSGRALFGADAPAEGIFFKLAGDLLP
GVLAGIVAAAILSAIMSTVDSQLLVASGAISHDLGAARLMGGRTVLATRLAMLVVSGVAVVLTLALPATIFDRTLFAWTA
LGASFGPVVVVRAFGGRPGGAAVLASILAGFVTSLAYEFVLNSGPGAVWARTVPWIAAFLALAVTRIVAGQHNQALGAPS
DL
>Mature_482_residues
MRANLPALITLIVYAVLLVGVSLWASRKVRSEASSFLLGGRSLGPLVSGLAYAASSSSAWVLLGYSGFVYATGLSALWMI
PGILLGYGAVWLFAGPVLQAASRDKDQLTLTAFLTETAGPRVARLIRISATVMIAFCFSYYIASQFQGAGVAFDDLFGIG
MSGGIILGAIIILAYTFAGGFLAVSVINTVQGVIMMLVAILLPVLAFSAAGGVSGIGAALEDVPPEYLATFGGRAGWIAG
GFALGMTATGFGALGQPHLISWIMAARDTKARVMGAGVAIGWGAVVYAGMAVLGLSGRALFGADAPAEGIFFKLAGDLLP
GVLAGIVAAAILSAIMSTVDSQLLVASGAISHDLGAARLMGGRTVLATRLAMLVVSGVAVVLTLALPATIFDRTLFAWTA
LGASFGPVVVVRAFGGRPGGAAVLASILAGFVTSLAYEFVLNSGPGAVWARTVPWIAAFLALAVTRIVAGQHNQALGAPS
DL

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=418, Percent_Identity=30.8612440191388, Blast_Score=176, Evalue=5e-44,
Organism=Escherichia coli, GI1787251, Length=456, Percent_Identity=32.6754385964912, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI87082237, Length=358, Percent_Identity=29.3296089385475, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790503, Length=408, Percent_Identity=23.0392156862745, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 48945; Mature: 48945

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRANLPALITLIVYAVLLVGVSLWASRKVRSEASSFLLGGRSLGPLVSGLAYAASSSSAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCE
VLLGYSGFVYATGLSALWMIPGILLGYGAVWLFAGPVLQAASRDKDQLTLTAFLTETAGP
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCH
RVARLIRISATVMIAFCFSYYIASQFQGAGVAFDDLFGIGMSGGIILGAIIILAYTFAGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FLAVSVINTVQGVIMMLVAILLPVLAFSAAGGVSGIGAALEDVPPEYLATFGGRAGWIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCCHHHH
GFALGMTATGFGALGQPHLISWIMAARDTKARVMGAGVAIGWGAVVYAGMAVLGLSGRAL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEE
FGADAPAEGIFFKLAGDLLPGVLAGIVAAAILSAIMSTVDSQLLVASGAISHDLGAARLM
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHH
GGRTVLATRLAMLVVSGVAVVLTLALPATIFDRTLFAWTALGASFGPVVVVRAFGGRPGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
AAVLASILAGFVTSLAYEFVLNSGPGAVWARTVPWIAAFLALAVTRIVAGQHNQALGAPS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DL
CC
>Mature Secondary Structure
MRANLPALITLIVYAVLLVGVSLWASRKVRSEASSFLLGGRSLGPLVSGLAYAASSSSAW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCE
VLLGYSGFVYATGLSALWMIPGILLGYGAVWLFAGPVLQAASRDKDQLTLTAFLTETAGP
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCH
RVARLIRISATVMIAFCFSYYIASQFQGAGVAFDDLFGIGMSGGIILGAIIILAYTFAGG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
FLAVSVINTVQGVIMMLVAILLPVLAFSAAGGVSGIGAALEDVPPEYLATFGGRAGWIAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCCHHHH
GFALGMTATGFGALGQPHLISWIMAARDTKARVMGAGVAIGWGAVVYAGMAVLGLSGRAL
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEE
FGADAPAEGIFFKLAGDLLPGVLAGIVAAAILSAIMSTVDSQLLVASGAISHDLGAARLM
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHH
GGRTVLATRLAMLVVSGVAVVLTLALPATIFDRTLFAWTALGASFGPVVVVRAFGGRPGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
AAVLASILAGFVTSLAYEFVLNSGPGAVWARTVPWIAAFLALAVTRIVAGQHNQALGAPS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]