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The map label for this gene is soxR [H]

Identifier: 114798478

GI number: 114798478

Start: 3566093

End: 3566548

Strand: Direct

Name: soxR [H]

Synonym: HNE_3426

Alternate gene names: 114798478

Gene position: 3566093-3566548 (Clockwise)

Preceding gene: 114799056

Following gene: 114800268

Centisome position: 96.25

GC content: 63.16

Gene sequence:

>456_bases
ATGTCCCTGAAACATTCCGACATCCTGACGATTGGCGAGTTGGCCGCGCGCACGGGCGTGGCCGTATCTGCGCTGCGCTA
TTACGAAGAACGCGGGCTTGTCCGCTCGCTGCGCGCGAAGGGCCAGCACCGGCGGTTCCTGCGCTCGGACATAAGGCGGG
TGTCGTTTATCCGGATCGCGCAATCGCTTGGCCTGACCATCGAAGATGTCGCCCAGGCCTTTGCCGCCCTGCCCGAGGGG
CGCACACCGACGGCGGCCGACTGGCGGGCCATCAGCGGGGATATTCGCGGCGTACTGGACCGCAAAATTGCAGAGCTGGA
AAACATGCGAGACAAGCTCGACAATTGCATCGGCTGCGGCTGTCTTTCTCTCAAACGCTGCGCGCTTTACAATGCCGGAG
ATGAGGCGGGTAAAACCGGAACGGGGCCGCGCTTTATCTTCCGCGACGGCCCCTGA

Upstream 100 bases:

>100_bases
TTGGGTTTGCCTGTGTCATGGCGGTTTCCCTTTCAGGGTGGTTGATGCCTGACACCTCTGCTACAATCTCAAGTTCACTT
TAGATCAAGCAGAAATTTGC

Downstream 100 bases:

>100_bases
ACTGTATTAGCCAACCCGCCGCGTCTGCCCGCGCCAATAGGGCTCGCGCAAATCCTTGCGGAGGATCTTGCCCGAGGGGT
TGCGTGGCAAGGCCTCAATG

Product: redox-sensitive transcriptional activator SoxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MSLKHSDILTIGELAARTGVAVSALRYYEERGLVRSLRAKGQHRRFLRSDIRRVSFIRIAQSLGLTIEDVAQAFAALPEG
RTPTAADWRAISGDIRGVLDRKIAELENMRDKLDNCIGCGCLSLKRCALYNAGDEAGKTGTGPRFIFRDGP

Sequences:

>Translated_151_residues
MSLKHSDILTIGELAARTGVAVSALRYYEERGLVRSLRAKGQHRRFLRSDIRRVSFIRIAQSLGLTIEDVAQAFAALPEG
RTPTAADWRAISGDIRGVLDRKIAELENMRDKLDNCIGCGCLSLKRCALYNAGDEAGKTGTGPRFIFRDGP
>Mature_150_residues
SLKHSDILTIGELAARTGVAVSALRYYEERGLVRSLRAKGQHRRFLRSDIRRVSFIRIAQSLGLTIEDVAQAFAALPEGR
TPTAADWRAISGDIRGVLDRKIAELENMRDKLDNCIGCGCLSLKRCALYNAGDEAGKTGTGPRFIFRDGP

Specific function: Activates The Transcription Of The Soxs Gene Which Itself Controls The Superoxide Response Regulon. Soxr Contains A 2fe-2s Iron-Sulfur Cluster That May Act As A Redox Sensor System That Recognizes Superoxide. The Variable Redox State Of The Fe-S Cluster I

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790498, Length=139, Percent_Identity=48.9208633093525, Blast_Score=143, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR010211
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16620; Mature: 16489

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKHSDILTIGELAARTGVAVSALRYYEERGLVRSLRAKGQHRRFLRSDIRRVSFIRIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
QSLGLTIEDVAQAFAALPEGRTPTAADWRAISGDIRGVLDRKIAELENMRDKLDNCIGCG
HHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
CLSLKRCALYNAGDEAGKTGTGPRFIFRDGP
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCC
>Mature Secondary Structure 
SLKHSDILTIGELAARTGVAVSALRYYEERGLVRSLRAKGQHRRFLRSDIRRVSFIRIA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
QSLGLTIEDVAQAFAALPEGRTPTAADWRAISGDIRGVLDRKIAELENMRDKLDNCIGCG
HHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
CLSLKRCALYNAGDEAGKTGTGPRFIFRDGP
HHHHHHHHHCCCCCCCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]