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The map label for this gene is acdA [H]

Identifier: 114798372

GI number: 114798372

Start: 3075203

End: 3076402

Strand: Direct

Name: acdA [H]

Synonym: HNE_2917

Alternate gene names: 114798372

Gene position: 3075203-3076402 (Clockwise)

Preceding gene: 114800388

Following gene: 114797771

Centisome position: 83.0

GC content: 60.17

Gene sequence:

>1200_bases
ATGGACTTCAATGATACCCCCGAAGAAGCCGCCTTCCGCAAGGAGGCTAACGCCTTCCTCTCCAAGCATCTCGAGCTGAA
GGCAGGCGCCAAACCCCGCCAGGCCAACGAGTCTGCCCTTGCCCGCGCGAAAGCCTGGCAAAAGACCAAAGCCGAAAACA
AGTTCGCCCAGATCACCTGGCCGAAGGAATGGGGCGGCCGCGGCGGCACCTCGATGGAAGCTGTTATCTGGGGCCAGGAA
GAAGCCAAGTATGACGCGCCAACCGGCCCGTTCGCCATTGGCCTGGGCATGTGTATCCCCACCGTGATCGCCTTCGGTTC
TGAAGAGCACAAGAAGAAGTATGTCCAGAAAGCGCTGTTCGGCGAAGAAGTCTGGTGCCAGCTCTTCTCCGAACCGTCTG
CCGGTTCTGACGTTGCCGGCCTCAAGACCCGCGCCGTGAAAGATGGCGATGAGTGGGTGATCAACGGCCAGAAGGTCTGG
ACGTCGGGCGCGCACTATTCCGACTACGGCATTCTGCTGGTCCGCACCGATCCCAAAGTGCCAAAGCACAAGGGCCTCAC
CATGTTCATCGTGAACATGAAACAGCCCGGCGTTGAAGTTCGCCCGATCCACCAGGCTTCCGGTGGCCGCGAATTCAACG
AAGTCTATTTCACGGATGTCCGCATTCCTGACAGCGACCGCCTGGGCGAAGTCGGCGCAGGCTGGAAAGTGGCCCTCGTG
ACCCTGATGAACGAGCGTCTCGCCGTTGGCGGCTCGCCCGGTCCCGACTGGGGTGAGATCATGGCCTATGCCAAGACCGC
CGGTTCGATGGATGATCAGGCCTTCCGCGAAAAGCTGGCTGACTGGTATGTGGCCGCGCAAGGCTACAAGCTAACGAAAT
TCCGTACCCAGACTGCCCTTTCTCGCGGTCAGACGCCGGGTCCGGAAAACTCGATCGGCAAGATCATCACGGCCAACCAC
CTGCAGGACATCTGTAACTCGGCCATCGAGATGCAGGACCATTACGGTATCATGACCGATACCGACAAAATGCCGGCCGA
TGCCATCTTCCAGCAGAGCTTCATGTGGGCGCCGGGTCTGCGCATTGCGGGCGGCACAGACGAGATCCTGAAGAACATCA
TCGCCGAGCGCGTTCTTGGCCTGCCCCAGGATGTCCGCGTCGACAAGGATCGCGCCTTCGACGAGATGAAGTCGGGCTGA

Upstream 100 bases:

>100_bases
GCACACGGCAAAAAAATCCGGGGAGAAATCCTCGCCCCCAAGACCCTACAGACCAATATAATTAGAACAGAAACACTGAA
GAAAACGAACGGAGTGCCCC

Downstream 100 bases:

>100_bases
TCGACCTTACATTTTTCAGACGCTGAAGCGCCGGTCCCGTTATTGCGGGGCCGGCGTTTCTGATTCTGGCTCAGGCTCTG
GCAGCGCTGTTGCCGCAATG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MDFNDTPEEAAFRKEANAFLSKHLELKAGAKPRQANESALARAKAWQKTKAENKFAQITWPKEWGGRGGTSMEAVIWGQE
EAKYDAPTGPFAIGLGMCIPTVIAFGSEEHKKKYVQKALFGEEVWCQLFSEPSAGSDVAGLKTRAVKDGDEWVINGQKVW
TSGAHYSDYGILLVRTDPKVPKHKGLTMFIVNMKQPGVEVRPIHQASGGREFNEVYFTDVRIPDSDRLGEVGAGWKVALV
TLMNERLAVGGSPGPDWGEIMAYAKTAGSMDDQAFREKLADWYVAAQGYKLTKFRTQTALSRGQTPGPENSIGKIITANH
LQDICNSAIEMQDHYGIMTDTDKMPADAIFQQSFMWAPGLRIAGGTDEILKNIIAERVLGLPQDVRVDKDRAFDEMKSG

Sequences:

>Translated_399_residues
MDFNDTPEEAAFRKEANAFLSKHLELKAGAKPRQANESALARAKAWQKTKAENKFAQITWPKEWGGRGGTSMEAVIWGQE
EAKYDAPTGPFAIGLGMCIPTVIAFGSEEHKKKYVQKALFGEEVWCQLFSEPSAGSDVAGLKTRAVKDGDEWVINGQKVW
TSGAHYSDYGILLVRTDPKVPKHKGLTMFIVNMKQPGVEVRPIHQASGGREFNEVYFTDVRIPDSDRLGEVGAGWKVALV
TLMNERLAVGGSPGPDWGEIMAYAKTAGSMDDQAFREKLADWYVAAQGYKLTKFRTQTALSRGQTPGPENSIGKIITANH
LQDICNSAIEMQDHYGIMTDTDKMPADAIFQQSFMWAPGLRIAGGTDEILKNIIAERVLGLPQDVRVDKDRAFDEMKSG
>Mature_399_residues
MDFNDTPEEAAFRKEANAFLSKHLELKAGAKPRQANESALARAKAWQKTKAENKFAQITWPKEWGGRGGTSMEAVIWGQE
EAKYDAPTGPFAIGLGMCIPTVIAFGSEEHKKKYVQKALFGEEVWCQLFSEPSAGSDVAGLKTRAVKDGDEWVINGQKVW
TSGAHYSDYGILLVRTDPKVPKHKGLTMFIVNMKQPGVEVRPIHQASGGREFNEVYFTDVRIPDSDRLGEVGAGWKVALV
TLMNERLAVGGSPGPDWGEIMAYAKTAGSMDDQAFREKLADWYVAAQGYKLTKFRTQTALSRGQTPGPENSIGKIITANH
LQDICNSAIEMQDHYGIMTDTDKMPADAIFQQSFMWAPGLRIAGGTDEILKNIIAERVLGLPQDVRVDKDRAFDEMKSG

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=252, Percent_Identity=31.3492063492063, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4501857, Length=399, Percent_Identity=25.8145363408521, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI4557233, Length=333, Percent_Identity=27.027027027027, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI187960098, Length=332, Percent_Identity=29.2168674698795, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4557231, Length=332, Percent_Identity=29.2168674698795, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI226958414, Length=200, Percent_Identity=33.5, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4501859, Length=190, Percent_Identity=34.2105263157895, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI76496475, Length=397, Percent_Identity=25.6926952141058, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=397, Percent_Identity=25.6926952141058, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7656849, Length=344, Percent_Identity=24.1279069767442, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI21361497, Length=367, Percent_Identity=24.7956403269755, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38505218, Length=304, Percent_Identity=26.6447368421053, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI87081958, Length=353, Percent_Identity=25.7790368271955, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786223, Length=305, Percent_Identity=23.9344262295082, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=389, Percent_Identity=28.2776349614396, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17569725, Length=337, Percent_Identity=29.9703264094956, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=202, Percent_Identity=34.6534653465347, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17534899, Length=233, Percent_Identity=33.9055793991416, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71990804, Length=202, Percent_Identity=34.6534653465347, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=204, Percent_Identity=34.3137254901961, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=395, Percent_Identity=23.5443037974684, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=194, Percent_Identity=35.0515463917526, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71982178, Length=193, Percent_Identity=32.6424870466321, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=330, Percent_Identity=23.6363636363636, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=330, Percent_Identity=24.5454545454545, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=343, Percent_Identity=23.6151603498542, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=323, Percent_Identity=24.4582043343653, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=178, Percent_Identity=29.2134831460674, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=312, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531909, Length=116, Percent_Identity=32.7586206896552, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24660351, Length=300, Percent_Identity=31.3333333333333, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21355753, Length=356, Percent_Identity=28.9325842696629, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21356377, Length=336, Percent_Identity=25.8928571428571, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=28.1159420289855, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666513, Length=205, Percent_Identity=33.6585365853659, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24646207, Length=335, Percent_Identity=25.6716417910448, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44007; Mature: 44007

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNDTPEEAAFRKEANAFLSKHLELKAGAKPRQANESALARAKAWQKTKAENKFAQITW
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEC
PKEWGGRGGTSMEAVIWGQEEAKYDAPTGPFAIGLGMCIPTVIAFGSEEHKKKYVQKALF
CHHHCCCCCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GEEVWCQLFSEPSAGSDVAGLKTRAVKDGDEWVINGQKVWTSGAHYSDYGILLVRTDPKV
CHHHHHHHHCCCCCCCCCCCCHHHEECCCCCEEECCCEEEECCCCCCCCEEEEEECCCCC
PKHKGLTMFIVNMKQPGVEVRPIHQASGGREFNEVYFTDVRIPDSDRLGEVGAGWKVALV
CCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHH
TLMNERLAVGGSPGPDWGEIMAYAKTAGSMDDQAFREKLADWYVAAQGYKLTKFRTQTAL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHH
SRGQTPGPENSIGKIITANHLQDICNSAIEMQDHYGIMTDTDKMPADAIFQQSFMWAPGL
HCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCC
RIAGGTDEILKNIIAERVLGLPQDVRVDKDRAFDEMKSG
EECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDFNDTPEEAAFRKEANAFLSKHLELKAGAKPRQANESALARAKAWQKTKAENKFAQITW
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEC
PKEWGGRGGTSMEAVIWGQEEAKYDAPTGPFAIGLGMCIPTVIAFGSEEHKKKYVQKALF
CHHHCCCCCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GEEVWCQLFSEPSAGSDVAGLKTRAVKDGDEWVINGQKVWTSGAHYSDYGILLVRTDPKV
CHHHHHHHHCCCCCCCCCCCCHHHEECCCCCEEECCCEEEECCCCCCCCEEEEEECCCCC
PKHKGLTMFIVNMKQPGVEVRPIHQASGGREFNEVYFTDVRIPDSDRLGEVGAGWKVALV
CCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHH
TLMNERLAVGGSPGPDWGEIMAYAKTAGSMDDQAFREKLADWYVAAQGYKLTKFRTQTAL
HHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHH
SRGQTPGPENSIGKIITANHLQDICNSAIEMQDHYGIMTDTDKMPADAIFQQSFMWAPGL
HCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCC
RIAGGTDEILKNIIAERVLGLPQDVRVDKDRAFDEMKSG
EECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]