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The map label for this gene is cobU [H]

Identifier: 114798312

GI number: 114798312

Start: 1555128

End: 1555634

Strand: Reverse

Name: cobU [H]

Synonym: HNE_1521

Alternate gene names: 114798312

Gene position: 1555634-1555128 (Counterclockwise)

Preceding gene: 114799223

Following gene: 114799067

Centisome position: 41.99

GC content: 55.23

Gene sequence:

>507_bases
ATGACAACCACTTTACTCTTAGGAGGGGCCAGATCCGGCAAGAGCCGCCGAGCACAGGACTTGGCAGAGAATATTTCGCC
ATGCCGTGTTTTTATTGCTACTGCCGAACCTTTGGACGAAGAGATGGCAAGCAGGATTGAGCGGCATCAGGCAGACCGCA
CCACGGGATGGCGTATGATCGAAACTCCGCTGAATCTGGTTGCCGCGCTGGGCGAAGCCAAGGATAATGAAGTCATCGTT
GTCGATTGCCTGACGCTATGGCTCTCCAATCTGATGCATCATGACTGGAGTGTGAACGCCGAAATTGACAGGCTCTGCAC
CACACTTGGCTCCATGAGCACGCCGGTGTTTCTCGTTTCGAACGAAATTGGCTTGGGACTTGTACCAGAAACGAAACTGG
GCCGTTCCTTCCGCGATGCACAGGGGCGGCTCAATCAGCGTGTCGCTTCAGTTTGCGACGTTGTCGAATTCATCGCTGCG
GGCCTGCCGCTGCGCCTCAAGTCGTGA

Upstream 100 bases:

>100_bases
TCGAAGAAGGCAGGCCGCCAAAACGCTTCTGAAAACAGTCCTTTAAATTACGCCGTTCCGTGAATAGGAACTGGGGCGCT
CAAGCGAGAGGACCAGCGTA

Downstream 100 bases:

>100_bases
GGGCAGCCAGCAGGCGATCTTCGGCCTTCTCGTTCTCGGGAAGTCCGATCCGCACAAGCCGGTCGCTCCAGGCAAACCGG
CGAACATAAATCCCCCTATG

Product: cobinamide kinase / cobinamide phosphate guanyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTTTLLLGGARSGKSRRAQDLAENISPCRVFIATAEPLDEEMASRIERHQADRTTGWRMIETPLNLVAALGEAKDNEVIV
VDCLTLWLSNLMHHDWSVNAEIDRLCTTLGSMSTPVFLVSNEIGLGLVPETKLGRSFRDAQGRLNQRVASVCDVVEFIAA
GLPLRLKS

Sequences:

>Translated_168_residues
MTTTLLLGGARSGKSRRAQDLAENISPCRVFIATAEPLDEEMASRIERHQADRTTGWRMIETPLNLVAALGEAKDNEVIV
VDCLTLWLSNLMHHDWSVNAEIDRLCTTLGSMSTPVFLVSNEIGLGLVPETKLGRSFRDAQGRLNQRVASVCDVVEFIAA
GLPLRLKS
>Mature_167_residues
TTTLLLGGARSGKSRRAQDLAENISPCRVFIATAEPLDEEMASRIERHQADRTTGWRMIETPLNLVAALGEAKDNEVIVV
DCLTLWLSNLMHHDWSVNAEIDRLCTTLGSMSTPVFLVSNEIGLGLVPETKLGRSFRDAQGRLNQRVASVCDVVEFIAAG
LPLRLKS

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=179, Percent_Identity=36.8715083798883, Blast_Score=116, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18459; Mature: 18328

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLLLGGARSGKSRRAQDLAENISPCRVFIATAEPLDEEMASRIERHQADRTTGWRMI
CCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEH
ETPLNLVAALGEAKDNEVIVVDCLTLWLSNLMHHDWSVNAEIDRLCTTLGSMSTPVFLVS
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEE
NEIGLGLVPETKLGRSFRDAQGRLNQRVASVCDVVEFIAAGLPLRLKS
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
TTTLLLGGARSGKSRRAQDLAENISPCRVFIATAEPLDEEMASRIERHQADRTTGWRMI
CCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEH
ETPLNLVAALGEAKDNEVIVVDCLTLWLSNLMHHDWSVNAEIDRLCTTLGSMSTPVFLVS
HHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEE
NEIGLGLVPETKLGRSFRDAQGRLNQRVASVCDVVEFIAAGLPLRLKS
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]